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Tytuł:
A study of knowledge attitude practices and identification of perceived barriers towards screening for diabetic retinopathy amongst diabetics in an industrial area in western Maharashtra
Autorzy:
Bakare, Prachi
Sethi, Sejal
Mushtaq, Iqra
Maheshgauri, Rupali
Magdum, Renu
Kamalkishor Modani, Neha
Gogate, Parikshit
Powiązania:
https://bibliotekanauki.pl/articles/29519441.pdf
Data publikacji:
2023-09-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
awareness
barriers to diabetic retinopathy screening
diabetic retinopathy screening
knowledge
Opis:
Introduction and aim. Nursing fields begin to face a wide variety of challenges when they first enter clinical practice. The aim of this study is to determine the difficulties experienced in patient communication by nursing students taking the clinical practice course for the first time. Material and methods. Focus group interview design was used for this study. Focus group design is used to give information about the opinions and experiences of the sample group on any subject. It is reported as a convenient design to identify different perspectives on a subject within the scope of the sample. Focus group interviews are a widely used method as data collection technique. Results. The findings of the study continue on 4 main themes at level 3, by identifying the similarities and differences in the codes determined by the three experts (researchers consulted and the researcher conducting/reporting the study). The findings of the study were evaluated in comparison with the findings of the studies reached in the literature and conducted in regions such as Israel, Iran, Sri-Lanka, Kenya, and Africa. Conclusion. There are many problems in student-patient communication in many different dimensions. The difficulties arising due to these problems generally focus on unknown clinical environment, lack of knowledge, differences between theory and practice, and mentor interaction.
Źródło:
European Journal of Clinical and Experimental Medicine; 2023, 3; 539-545
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Resveratrol and curcumin against diabetic retinopathy. Better together than apart
Autorzy:
Kabiesz, Adam
Powiązania:
https://bibliotekanauki.pl/articles/51789549.pdf
Data publikacji:
2023-12-31
Wydawca:
Medical Education
Tematy:
resveratrol
curcumin
diabetic retinopathy
antioxidant
oxidative stress
Opis:
The health-promoting effects of curcumin and resveratrol have been known for a long time. The most important features of polyphenols include their effect on blood vessels and participation in the neutralization of free oxygen radicals. Both resveratrol and curcumin exhibit antioxidant effects, and the combined use of both substances significantly improves their effectiveness. In the fight against diabetic retinopathy, the antiangiogenic effect of polyphenols also turn out to be important. Many researchers also point to the possibility of using resveratrol and curcumin in cancer therapy.
Źródło:
OphthaTherapy; 2023, 10, 4; 284-288
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Supplementation in diet of patients with retinal diseases
Autorzy:
Święch, Anna
Teper, Sławomir
Gawęcki, Maciej
Nowińska, Anna
Figurska, Małgorzata
Adamiec-Mroczek, Joanna
Karska-Basta, Izabella
Kucharczuk, Jan
Powiązania:
https://bibliotekanauki.pl/articles/51789555.pdf
Data publikacji:
2024-03-31
Wydawca:
Medical Education
Tematy:
supplementation
diet
retinal diseases
AMD
diabetic retinopathy
Opis:
Etiology of retinal diseases, such as age-related macular degeneration or diabetic retinopathy is multifactorial, where oxidative stress and inflammation play an important role. Therefore supplementation of diet in that group of patients with proper product, which contains substances with anti-oxidant and anti-inflammatory properties is advised for reducing the risk of progression of such diseases.
Źródło:
OphthaTherapy; 2024, 11, 1; 14-23
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Troxerutin in the treatment of eye diseases - a proven substance rediscovered
Autorzy:
Bernardczyk-Meller, Jadwiga
Powiązania:
https://bibliotekanauki.pl/articles/23202887.pdf
Data publikacji:
2023-09-30
Wydawca:
Medical Education
Tematy:
diabetic retinopathy
subconjunctival haemorrhage
troxerutin
eye drops
Opis:
Troxerutin is a well and for a long time known substance, it is a semi-synthetic bioflavonoid derived from rutin. Original substance is supplied from flowers of Styphnolobium japonicum tree. The author discusses actual medical effects of troxerutin, including antioxidant, anti-inflammatory, antithrombosis and protecting endothelium of small vessels. Being water-soluble, it can be used as ophthalmic drops in treatment of subconjunctival haemorrhage, vitreous haemorrhage and early stages of diabetic retinopathy.
Źródło:
OphthaTherapy; 2023, 10, 3; 201-204
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
AGEs interactions with RAGE and their contribution to diabetic retinopathy
Autorzy:
Solan, Anna
Kempka, Katarzyna
Kamiński, Piotr
Bogdzińska, Maria
Malukiewicz, Grażyna
Powiązania:
https://bibliotekanauki.pl/articles/1075668.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
RAGE
diabetic retinopathy
molecular basis
polimorphism
signaling pathway
Opis:
Diabetic retinopathy as a complication of diabetes is one of the most common causes of vision loss. It is a dangerous disease, which affects more and more people. It is important to know its different causes, background and to generate new, effective therapeutic threatments. One of the possible causes of diabetic retinopathy is the accumulation of advanced glycation products and over-expression of AGEs receptors (RAGE) leading to tissue damage, oxidative stress formation, and the promotion of other changes and disorders. There are many genetic variants that encode the AGEs receptor (RAGE). Some polymorphisms (Gly82Ser, 1704G/T, 2184A/G, -429T/C, -374T/A) may be associated with diabetic retinopathy. This paper aims to systematize knowledge in this field and to show the relationship between these compounds and diabetic retinopathy.
Źródło:
World Scientific News; 2019, 119; 41-51
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Levels of physical activity in people with diabetes residing in Spain
Niveles de actividad física en personas con diabetes residentes en España
Autorzy:
González-Carcelén, Carmen M.
Nicolás López, Jonathan
López Sánchez, Guillermo Felipe
Powiązania:
https://bibliotekanauki.pl/articles/1491126.pdf
Data publikacji:
2020-01-03
Wydawca:
Atena Research Association
Tematy:
Physical activity
Mediterranean diet
Diabetes
Diabetic retinopathy
Spain
Opis:
Objectives: The aim of this study was to analyze the level of physical activity in people with diabetes, depending on their characteristics. Methods: The sample consisted of 81 participants with type 1 and type 2 diabetes and belonging to a diabetes care association. First of all, the participants completed the short version of the International Physical Activity Questionnaire and the Mediterranean Diet Adherence Questionnaire online. Subsequently, they indicated their sex, age, type of diabetes, the presence of other complications and the years since diagnosis. In addition, data on consumption of tobacco and alcohol, glycosylated hemoglobin and fasting glucose were collected. For the analysis of the data, t-test for independent samples was used to compare means between categories, always with a level of significance of p <.05. Furthermore, effect size was calculated through Cohen’s d. Finally, the frequency and the percentage of the variables were calculated. Findings: The results showed in all the categories an average level of physical activity higher than the recommendations of physical activity for people with diabetes, being the level of physical activity predominantly moderate. Although women also complied with the recommendations for physical activity, their level of physical activity was significantly lower than the level of men Conclusions: It is recommended to expand the research on the barriers and motivations found by people with diabetes to practice physical activity, playing special attention to women with diabetes.
Źródło:
Atena Journal of Public Health; 2020, 2; 2-2
2695-5911
Pojawia się w:
Atena Journal of Public Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Subthreshold micropulse yellow 577 nm laser therapy of diabetic macular oedema in rural and urban patients of south-eastern Poland
Autorzy:
Latalska, Małgorzata
Prokopiuk, Agata
Wróbel-Dudzińska, Dominika
Mackiewicz, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/989023.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
diabetic maculopathy
macular edema
laser treatment
micropulse laser
diabetic retinopathy
Opis:
Objectiv. To evaluate the efficacy of subthreshold micropulse yellow (577 nm) laser photocoagulation in diffuse macular edema (DME) in rural and urban patients of south-eastern Poland. Materials and method. Seventy-five eyes of 75 patients with diffuse DME were treated with subthreshold micropulse yellow laser photocoagulation with a 5% duty cycle at an energy level. The laser exposure time was 20 ms and the spot diameter was 100 μm. Best corrected visual acuity (BCVA), reading vision (Snellen) and optical coherence tomography-determined central retinal thickness (CRT) were estimated before and 2, 4 and 6 months after laser treatment. There were no statistically important differences in: the advancement of DME, HbA1c (glycated hemoglobin) level, duration of diabetes mellitus (DM), the degree of vision damage between rural and urban patients. Results. The follow-up was 6 months later. The baseline BCVA was 0.20 and remained stable- 0.3 after 6 months. The Snellen at baseline was 1.0 and improved to 0.5 finally (p=0.0004). The CRT at baseline was 500 μm and changed to 346 μm (p=0.00000) at the final follow-up. Finally, no retinal damage was observed. Conclusions. Place of residence had no statistically significant effect on the demographics data, baseline visual acuity, reading visual acuity and central retinal thickness. Subthreshold micropulse yellow laser showed a highly significant efficiency in the treatment of DME. The effects of the treatment were more significant in rural patients than in urban ones.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Barriers to physical activity in people with diabetes residing in Spain
Barreras para la práctica de actividad física en personas con diabetes residentes en España
Autorzy:
Nicolás López, Jonathan
González Carcelén, Carmen M.
López Sánchez, Guillermo Felipe
Powiązania:
https://bibliotekanauki.pl/articles/1491127.pdf
Data publikacji:
2020-01-03
Wydawca:
Atena Research Association
Tematy:
Barriers
Physical activity
Mediterranean diet
Diabetes
Diabetic retinopathy
Spain
Opis:
Objectives: The objective of the present study was to perform an analysis of the barriers to the practice of physical activity and diet in people with diabetes mellitus residing in Spain. Methods: Ninety participants (40 men and 50 women) with type 1 diabetes mellitus (71) and type 2 diabetes mellitus (19) residing in Spain, and aged between 12 and 80 years (average age 41.12 ± 17.04) were part of the present study. The participants were asked about the sociodemographic variables of sex and age, as well as the type of diabetes, the presence of other associated pathologies and the years elapsed since their diagnosis. The participants were also asked about the consumption of tobacco and alcohol. Afterwards, the barriers or difficulties perceived in relation to physical exercise were assessed through the Barriers Self-Report for the Practice of Physical Activity (BSPPA) and the diet with the Questionnaire of Adherence to the Mediterranean Diet (MEDAS-14). Then, the participants provided information regarding their last blood test with respect to the levels of glycosylated hemoglobin (HbA1c) and fasting glucose. A descriptive analysis was carried out to present the characteristics of the sample as well as the barriers for the practice of physical activity presented by the sample studied. Finally, a comparison analysis of means was carried out using the Student's t test for independent samples, showing the significant differences between the barriers for the practice of physical activity according to the characteristics of the sample. Findings: The data showed how the Obligations / Lack of time factor represents the main barrier to the practice of physical activity in this population, especially in women, in those under 65 and in people with type 1 diabetes. Conclusions: In general, it is observed that all those categories that may indicate a less healthy lifestyle have a greater degree of agreement with the perceived barriers.
Źródło:
Atena Journal of Public Health; 2020, 2; 3-3
2695-5911
Pojawia się w:
Atena Journal of Public Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sulodexide: A new model for treating the early stages of diabetic retinopathy
Autorzy:
Wylęgała, Adam
Powiązania:
https://bibliotekanauki.pl/articles/51789546.pdf
Data publikacji:
2023-12-04
Wydawca:
Medical Education
Tematy:
glycocalyx
hard exusdates
sulodexide
diabetic retinopathy
blood vessel protection
Opis:
Glycocalyx is the surface layer of endothelial cells, it lines the blood vessels and provides a cellular barrier against damage. Sulodexide has a protective effect on the glycocalyx and allows it to be rebuilt, and has anti-inflammatory, antioxidant, anticoagulant, and lipid profile-enhancing properties. Diabetic retinopathy damages the glycocalyx and vascular endothelium in the retina. Sulodexide rebuilds the glycocalyx and increases the integrity of the blood-retinal barrier, thereby protecting the retinal vasculature retina from hyperglycemia-induced damage. Clinical studies have confirmed that in non-proliferative diabetic retinopathy, sulodexide improves visual acuity, reduces microaneurysms and hard exudates. Further in a study evaluating recurrent retinal vein thrombosis, sulodexide reduced the recurrence rate. Sulodexide is a safe and well-tolerated drug and may play an important role in the treatment of diabetic retinopathy, both in reducing symptoms and improving visual function.
Źródło:
OphthaTherapy; 2023, 10, 4; 269-276
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The association between ALR2 -106C > T gene polymorphisms and diabetic retinopathy susceptibility in diabetes mellitus patient: a systematic review and meta-analysis
Autorzy:
Putri, Indah Sagitaisna
Rezkita, Bastomy Eka
Irving, Steven
Azmiardi, Akhmad
Powiązania:
https://bibliotekanauki.pl/articles/4175390.pdf
Data publikacji:
2023-03-27
Wydawca:
Medical Education
Tematy:
ALR2 gene
diabetic retinopathy
diabetes mellitus
gene polymorphism
polyol pathway
Opis:
Aldose reductase gene polymorphisms has been indicated to be associated with diabetic retinopathy (DR). The research data were from PubMed and EMBASE. We identified -106C > T single nucleotide polymorphism (SNP). Pool odds ratio (OR) with 95% CI were calculated. Nine studies were included. ALR2 106C > T gene polymorphisms was associated with the increased risk of DR in T1DM (C vs. T, OR = 2.07, p = 0.001; CC vs. CT + TT, OR = 2.56, p = 0.005). T allele and TT genotype were associated with decreased risk of DR in T1DM (OR = 0.48, p = 0.0001 and OR = 0.12, p = 0.0005). In conclusion, C allele and CC genotype may be a risk factor, while T allele and TT genotype may serve as protective factor for DR in T1DM patient.
Źródło:
OphthaTherapy; 2023, 10, 1; 12-21
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The way it was and the way it should be - the new approach to the treatment of nonproliferative diabetic retinopathy
Jak nie było, a jak powinno być – nowe podejście do leczenia nieproliferacyjnej retinopatii cukrzycowej
Autorzy:
Misiuk-Hojło, Marta
Kręcicka, Julia
Powiązania:
https://bibliotekanauki.pl/articles/2046661.pdf
Data publikacji:
2021-12-06
Wydawca:
Medical Education
Tematy:
sulodexide
diabetes
diabetic retinopathy
microangiopathy
glycocalyx
sulodeksyd
cukrzyca
retinopatia cukrzycowa
mikroangiopatia
glikokaliks
Opis:
Diabetes has been declared an epidemic of the XXIst century by the World Health Organisation. Diabetic retinopathy, one of its main complications, is a leading cause of vision impairment among professionally active adults. Diabetic retinopathy is a microangiopathy that affects mainly small vessels, due to their highest vulnerability to hyperglycemia. Preventive measures involve mainly strict diabetic follow-ups, balanced level of glycated hemoglobin, blood pressure values and analysis of lipids. Regular ophthalmological check-ups and imaging tests of the retina are also extremely significant. For many years scientists have searched for a therapy to suppress vascular changes in diabetes. In May 2021 a stance on sulodexide use as a supporting treatment in mild and intermediate diabetic retinopathy was published by the Polish Society of Ophthalmology. Sulodexide protects vascular endothelium, contributes to endothelial cells’ function and has profibrinolytic, anti-inflammatory and vasoregulatory properties. These features make it a promising protective agent in the early stages of diabetic retinopathy.
Cukrzyca została uznana przez Światową Organizację Zdrowia za epidemię XXI w. Retinopatia cukrzycowa należy do głównych komplikacji cukrzycy i wiodących przyczyn utraty wzroku wśród aktywnych zawodowo dorosłych. Jest to mikroangiopatia, w której dochodzi do uszkodzenia głównie drobnych naczyń, ponieważ są one najbardziej wrażliwe na hiperglikemię. W ramach działań prewencyjnych kluczowe są adekwatne monitorowanie metaboliczne cukrzycy, w tym wyrównane wartości hemoglobiny glikowanej, ciśnienia tętniczego oraz lipidogramu. Niezwykle ważne są również regularne kontrole okulistyczne i okresowe badania obrazowe siatkówki. Od lat naukowcy poszukują terapii umożliwiającej zahamowanie zmian naczyniowych w cukrzycy. W maju 2021 r. Polskie Towarzystwo Okulistyczne opublikowało stanowisko grupy eksperckiej w zakresie stosowania sulodeksydu jako leczenia wspomagającego w łagodnej oraz średnio zaawansowanej retinopatii cukrzycowej. Sulodeksyd chroni śródbłonek naczyń, wpływa na czynność jego komórek, ma właściwości profibrynolityczne, przeciwzapalne i wazoregulujące. Cechy te czynią go obiecującym czynnikiem protekcyjnym w pierwszych fazach retinopatii cukrzycowej.
Źródło:
OphthaTherapy; 2021, 8, 4; 233-237
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hyperreflective dots in optical coherence tomography
Autorzy:
Paczwa, Katarzyna
Szabelska, Paulina
Rerych, Magdalena
Różycki, Radosław
Gołębiewska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/2159017.pdf
Data publikacji:
2022-09-30
Wydawca:
Medical Education
Tematy:
hyperreflective dots
HRDs
optical coherence tomography
AMD
diabetic retinopathy
retinal vein occlusion
Opis:
Optical coherence tomography is a non-invasive and repeatable imaging method of posterior segment of the eye used in medical practice. Hyperreflective dots visible in OCT scans have been reported in various retinal diseases such as age-related macular degeneration, diabetic macular edema, retinal vein occlusion and central serous chorioretinopathy. In the future, HRDs may become a useful biomarker in making treatment decision and monitoring ocular conditions among the patients with mentioned diseases.
Źródło:
OphthaTherapy; 2022, 9, 3; 175-179
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnozowanie stanu retinopatii cukrzycowej przy pomocy głębokich sieci neuronowych
Classification of the stage of the disease by deep neural networks
Autorzy:
Jarzembiński, B.
Kwasigroch, A.
Grochowski, M.
Powiązania:
https://bibliotekanauki.pl/articles/267831.pdf
Data publikacji:
2018
Wydawca:
Politechnika Gdańska. Wydział Elektrotechniki i Automatyki
Tematy:
uczenie głębokie
sieci neuronowe
retinopatia cukrzycowa
deep learning
neural networks
diabetic retinopathy
Opis:
W referacie opisano problem wykrywania oraz klasyfikacji stanu retinopatii cukrzycowej ze zdjęć dna oka przy pomocy głębokich sieci neuronowych. Retinopatia cukrzycowa jest chorobą oczu często występującą u osób z cukrzycą. Nieleczona prowadzi do uszkodzenia wzroku, a nawet ślepoty. W pracy badawczej opracowano system wykrywania retinopatii cukrzycowej na podstawie zdjęć dna oka. Opracowana sieć neuronowa przypisuje stan choroby w 5 stopniowej skali – od braku choroby do najbardziej zaawansowanego stanu choroby. Zaproponowano specjalny system kodowania klas w celu uchwycenia wielkości różnicy pomiędzy rzeczywistymi a predykowanymi stanami choroby. Uzyskano wysokie wyniki klasyfikacji na zbiorze testowym. W celu oceny skuteczności działania systemu wykorzystano miary statystyczne takie jak ważona Kappa i dokładność.
In the paper we described computer aided detection system of diabetic retinopathy based on fundus photos of retina. Diabetic retinopathy is an eye disease associated with diabetes. Non-treated diabetic retinopathy leads to sight degeneration and even blindness. Early detection is crucial due to provide effective treatment. Currently, diabetic retinopathy detection is time consuming process, done manualy by medical specialist. The disease is dangerous issue in places where the availability of phisicians is limited. We employed the computer system that detect diabetic retinopathy and assess a stage of the disease based on retinal photo of fundus. We used one of the best image classification system – deep neural networks. Employed system assess the stage of the disease in 5 level scale – from absence of disease to the most severe stage of disease. We employed transfer learning and data augmentation to enhance classification result. Moreover we proposed special class coding system to catch the difference between real and predicted stage of disease. We tested employed system using different statistical measures like accuracy, sensitivity, specificity and Kappa score.
Źródło:
Zeszyty Naukowe Wydziału Elektrotechniki i Automatyki Politechniki Gdańskiej; 2018, 60; 37-40
1425-5766
2353-1290
Pojawia się w:
Zeszyty Naukowe Wydziału Elektrotechniki i Automatyki Politechniki Gdańskiej
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Macrophages in Diabetes Mellitus: A Review on Understanding of Macrophage Function
Autorzy:
Chatterjee, Susraba
Guria, Srikanta
Powiązania:
https://bibliotekanauki.pl/articles/1059398.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Alloxan
Beta-cell Therapy
Cytokines
Diabetes mellitus
Diabetic Nephropathy
Diabetic Retinopathy
Macrophage
Macrophage Type 1
Macrophage Type 2
Streptozotocin
Opis:
Diabetes mellitus (DM) causes millions of deaths all over the world. Immune system contains macrophages that play very important role in DM. Excessive secretion of different cytokines can induce the DM development. Diabetes mellitus (DM) also affect the function of macrophage. We review the important findings regarding the role of macrophage in DM. This review may emphasize future direction towards development of novel immune-modulatory therapeutic intervention.
Źródło:
World Scientific News; 2019, 134, 2; 319-325
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ranibizumab w leczeniu cukrzycowego obrzęku plamki
Ranibizumab in the treatment of diabetic macular edema
Autorzy:
Bryl, Anna
Mrugacz, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1035146.pdf
Data publikacji:
2019
Wydawca:
Medical Education
Tematy:
cukrzyca
leczenie anty-VEGF
obrzęk plamki
retinopatia cukrzycowa
diabetes
diabetic retinopathy
macular edema
anti-VEGF treatment
Opis:
Diabetes is an important social problem. Epidemiological studies show a worldwide increase in the incidence of type 1 and 2 diabetes. Increasing duration of diabetes significantly raises the risk of the retinal vascular changes and the development of the macular edema. Ranibizumab in intravitreal injection has revolutionized the treatment of ocular complications of diabetes. It is used as part of the first-line treatment for clinically significant macular edema with occlusion and worsening of visual acuity. Numerous studies have demonstrated greater efficacy of the treatment with ranibizumab (both in monotherapy and in combination with laser therapy) compared to laser therapy, which was the gold standard of therapy.
Cukrzyca jest chorobą stanowiącą duży problem społeczny. Badania epidemiologiczne dotyczące zapadalności na cukrzycę typu 1 i 2 na świecie wykazują ciągły wzrost liczby zachorowań. Wraz ze wzrostem czasu trwania cukrzycy wzrasta prawdopodobieństwo znacznych zmian naczyniowych siatkówki i rozwoju obrzęku plamki. Zastosowanie ranibizumabu w iniekcji doszklistkowej zrewolucjonizowało leczenie powikłań ocznych cukrzycy. Lek ten stosowany jest w ramach leczenia pierwszego rzutu w przypadku klinicznie znamiennego obrzęku plamki z zajęciem dołka i pogorszeniem ostrości wzroku. W licznych badaniach wykazano większą skuteczność jego leczenia ranibizumabem – zarówno w monoteraii, jak i w skojarzeniu z laseroterapią – w porównaniu z laseroterapią, która do niedawna jeszcze była złotym standardem leczenia.
Źródło:
OphthaTherapy; 2019, 6, 2; 105-109
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 17

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