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Wyszukujesz frazę "Carcinogenic" wg kryterium: Temat


Tytuł:
Cadmium, Lead and Zinc in the Soil-Plant-Alpaca System and Potential Health Risk Assessment Associated with the Intake of Alpaca Meat in Huancavelica, Peru
Autorzy:
Orellana Mendoza, Edith
Pérez Saenz, Lilia
Custodio, María
Bulege, Wilfredo
Yallico, Luz
Cuadrado, Walter
Powiązania:
https://bibliotekanauki.pl/articles/1839190.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
bioaccumulation factor
heavy metals
alpaca meat
non-carcinogenic risk
carcinogenic risk
Opis:
The consumption of contaminated natural pastures with highly dangerous and toxic heavy metals such as cadmium (Cd) and lead (Pb) by Andean camelids could cause harmful effects on the health of people exposed via consumption of contaminated alpaca meat. The concentration of Cd, Pb and Zn in the soil-plant-alpaca system was determined and the potential health risk associated with the intake of alpaca meat was evaluated. Soil and grass samples were collected in grazing areas of the South American camelid, and in the Municipal Slaughterhouse of Huancavelica, 30 samples of alpaca pectoral muscle were collected. The concentrations of Cd in the soil, grass and alpaca muscle exceeded the threshold values of national and international standards. The bioaccumulation factor values of the three elements studied was less than 1, Cd was the element with the highest bioavailability and mobility in the soil-plant-alpaca muscle system. The mean concentration of Cd in muscle was 0.335 ± 0.088 mg/kg which exceeded the maximum level allowed by the FAO/WHO and the European Commission, the concentration of Pb and Zn did not exceed the regulated limits. No significant differences were detected in accumulation according to sex. The non-carcinogenic hazard index (HI) values for the studied metals indicated that there is no adverse health risk (HI < 1) for children and adults from alpaca meat intake, but they could experience carcinogenic risk from prolonged exposure to Cd, and for exceeding the 1×10–4 limit threshold. It is recommended to conduct further studies on the accumulation of potentially toxic elements in alpaca tissues in order to determine the possible total risk of heavy metals in consumer’s health.
Źródło:
Journal of Ecological Engineering; 2021, 22, 3; 40-52
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chemical pollution of environment in the cities of Central Siberia: risk for the health of the population
Chemiczne zanieczyszczenie środowiska w miastach Środkowej Syberii: zagrożenie dla zdrowia ludności
Autorzy:
Klimatskaya, Ludmila
Powiązania:
https://bibliotekanauki.pl/articles/1177599.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
Krasnoyarsk region
air pollution
carcinogenic and non-carcinogenic
food pollution
water pollution
Opis:
Introduction. This article will deal with environmental pollution in cities including the problem of risk assessment. The aim of the study is to determine carcinogenic and non-carcinogenic risks for the health of the population due to chemical contamination of air, water and food in the cities of the Krasnoyarsk region. Material and methods. The research was conducted in the Center of Hygiene and Epidemiology in the Krasnoyarsk region. 5122 samples of air, 4863 samples of water and 6915 samples of food stuff have been analyzed. Concentration of chemical substances was the base on which individual carcinogenesis risk (ICR) and population carcinogenic conventional risks (PCCR) and non carcinogenic risks [1] have been calculated. In the industrial cities chemical pollution of air, water and food stuff including carcinogenic substances creates carcinogenic and non-carcinogenic risks of morbidity of the population with the reinforcement of the complex impact, “with” which greatly exceeds the maximum acceptable risks. Results. Chemical pollution of environmental facilities in cities of the Krasnoyarsk region produce complex carcinogenic and non-carcinogenic risks which exceed maximum limit. The greatest shares in structure of complex carcinogenic risks are made in food stuff and water consumption in structure of complex non-carcinogenic risks as a result of air pollution and food stuff pollution. Conclusions. Obtained data could be used to set priorities in preventive measures to preserve health of the population in industrial cities of the Krasnoyarsk region.
Wstęp. Artykuł zajmuje się problemem zanieczyszczenia środowiska w miastach oraz problemem oceny ryzyka zdrowotnego. Celem pracy jest określenie ryzyka kancerogennego i niekancerogennego dla zdrowia populacji z powodu zanieczyszczenia powietrza, wody i żywności w miastach regionu Krasnojarskiego. Materiał i metody. Badania przeprowadzono w Centrum Higieny i Epidemiologii regionu Krasnojarskiego. Wykonano 5122 analizy powietrza, 4863 analizy wody i 6915 analiz żywności. Na podstawie stężenia substancji chemicznych obliczono indywidualne ryzyko kancerogenezy (ICR) oraz populacyjne umowne ryzyko kancerogenezy (PCCR) i ryzyko niekancerogenności. W miastach przemysłowych zanieczyszczenie chemiczne wody, powietrza i żywności, stwarza kancerogenne i niekancerogenne ryzyko zachorowalności populacyjnej, co jest potęgowane przez kompleksowy udział dodatkowych czynników i znacznie przekracza maksymalnie dopuszczalne ryzyko. Wyniki. Zanieczyszczenie chemiczne z obiektów środowiskowych w miastach krasnojarskich charakteryzuje kompleks kancerogennego i niekancerogennego ryzyka, które przekracza dopuszczalne maksimum. Największy udział w strukturze kompleksu ryzyka kancerogennego wykazuje konsumpcja żywności, natomiast udział wody pitnej wykazano w strukturze kompleksu ryzyka niekancerogennego, jako wynik skażenia powietrza i wody. Wnioski. Uzyskane dane powinny być wykorzystane celem określenia pierwszeństwa w kierunkach opracowywania działań zapobiegawczych dla zachowania zdrowia populacyjnego w przemysłowych miastach regionu Krasnojarska.
Źródło:
Medycyna Środowiskowa - Environmental Medicine; 2015, 18, 1; 12-17
1505-7054
2084-6312
Pojawia się w:
Medycyna Środowiskowa - Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Obesity as a tumour development triggering factor
Autorzy:
Budny, A.
Grochowski, C.
Kozłowski, P.
Kolak, A.
Kamińska, M.
Budny, B.
Abramiuk, M.
Burdan, F.
Powiązania:
https://bibliotekanauki.pl/articles/2082058.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
cancer
malignancy
overweight
carcinogenesis
carcinogenic
Opis:
Introduction. The overweight and obesity epidemic represents a rapidly growing threat to the health of populations in an increasing number of countries. Nearly one-third of the world’s population has excess adipose tissue. Nowadays, obesity occurrence is so common that it is replacing more traditional problems, such as an undernutrition and infectious diseases, as the most significant causes of ill health. If the current trend continues, almost half of the world’s adult population will be overweight or obese by 2030. Objective. The aim of this study is to show the connection between recent trends in body mass index, and the globally changing cancer profile. State of knowledge. A range of clinical and epidemiological studies have shown the relationship between excess body fat and the most frequently occurring malignancies. Obesity is associated with many cancers, such as: breast, colorectal, liver, lung, kidney, oesophageal, pancreatic, endometrium, ovarian, prostate, thyroid, and gallbladder cancer. Conclusions. In the light of this information, the study supports the claimed statement that obesity is one of the major health problems of the 21st century. Considering the increase in the number of obese people worldwide, it is necessary to develop a strategy allowing to prevent it. Fighting against unhealthy lifestyle in order to reduce overweight and obesity in society may have an essential impact on decreasing the number of incidences of cancer.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 13-23
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Causes and risk factors for skin cancer - the current state of knowledge
Autorzy:
Mędrzycka-Dąbrowska, W.
Gutysz-Wojnicka, A.
Powiązania:
https://bibliotekanauki.pl/articles/1917280.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
skin cancer
prevention skin cancer
major carcinogenic factors
Opis:
The most common cancer among all skin cancers is basal cell carcinoma. It occurs five times more likely than squamous cell carcinoma. In total, the incidence of skin cancer in Poland was in 2005, more than 4,300 new cases in women and nearly 4,000 men. Skin cancer is ranked in terms of the incidence of cancer, respectively, the 3 and 5 position. The incidence of skin cancer is associated with exposure to sunlight. Skin cancer most often locates on the exposed parts of the body (hands, face, neck, scalp - particularly in those balding). Most often affects people in 6 and 7 decade of life.The aim of the study was to present the carcinogenic factors responsible for the development of skin cancers and to briefly discuss individual skin cancers. We analysed Polish and foreign bibliography on the prevention of skin cancers based on the most recent reports.
Źródło:
Progress in Health Sciences; 2015, 5, 1; 225-231
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Night shift work characteristics and occupational co-exposures in industrial plants in Łódź, Poland
Autorzy:
Pepłońska, Beata
Burdelak, Weronika
Bukowska, Agnieszka
Krysicka, Jolanta
Konieczko, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/2179118.pdf
Data publikacji:
2013-08-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
industry
night shift work
occupational exposure
carcinogenic agents
Opis:
Objectives: Night shift work involving circadian rhythm disruption has been classified by IARC as a probably carcinogenic to humans (Group 2A). Little is known about co-exposures of the night shift work in occupational settings. The aim of our study was to characterize night shift work systems and industrial exposures occurring in the manufacturing plants in Łódź, Poland, where night shift work system operates, with particular focus on potential carcinogens. Material and Methods: Data on the night shift work systems and hazardous agents were collected through survey performed in 44 enterprises. The identified hazardous agents were checked using the IARC carcinogen list, and the harmonized EU classification of chemical substances. We also examined databases of the Central Register of Data on exposure to substances, preparations, agents and technological processes showing carcinogenic or mutagenic properties in Poland. Results: The most common system of work among studied enterprises employed 3 (8-hour) shifts within a 5-day cycle. We identified as many as 153 hazards occurring in the environment of the plants, with noise, carbon monoxide and formaldehyde recorded as the most common ones. Out of these hazards, 11 agents have been classified by IARC to group 1 - carcinogenic to humans, whereas 10 agents have been classified as carcino - gens by the regulation of European Classification of carcinogens. Analysis of the data from the Central Register revealed that 6 plants reported presence of carcinogens in the environment of work. Conclusions: In our study we observed that in none of the workplaces the night shift work was a single exposure. Further epidemiological studies focusing on investigation of health effects of the night shift work should identify occupational co -exposures and examine them as potential confounders.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2013, 26, 4; 522-534
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Podstawowe obowiązki pracodawcy w zakresie występowania czynników rakotwórczych i/lub mutagennych w środowisku pracy
Main obligations of the employer in terms of occurrence carcinogenic and/or mutagenic substances in environmental work
Autorzy:
Caban, A.
Stradomski, P.
Powiązania:
https://bibliotekanauki.pl/articles/103606.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Humanistyczno-Przyrodniczy im. Jana Długosza w Częstochowie. Wydawnictwo Uczelniane
Tematy:
czynniki rakotwórcze
czynniki mutagenne
carcinogenic substances
mutagens substances
Opis:
Występowanie w środowisku pracy substancji rakotwórczych i/lub mutagennych stanowi bezpośrednie zagrożenie dla zdrowia lub życia osób narażonych na ich oddziaływanie. Oprócz standardowych obowiązków w zakresie bhp, na barkach pracodawcy spoczywają więc dodatkowe zadania wynikające z art. 222 § 1 K.p. W artykule omówiono szczegółowe reguły postępowania określone w Rozporządzeniu Ministra Zdrowia z dnia 24 lipca 2012 r. w sprawie substancji chemicznych, ich mieszanin, czynników lub procesów technologicznych o działaniu rakotwórczym lub mutagennym w środowisku pracy oraz zharmonizowaną klasyfikację kancerogenów i mutagenów. Celem wypełnienia nałożonych na pracodawcę obowiązków jest objęcie właściwą opieką zdrowotną pracowników zawodowo narażonych na kancerogeny i podjęcie szeroko rozumianych działań profilaktycznych.
The occurrence in the workplace carcinogens and / or mutagens substances is a direct threat to the health or life of people exposed to their influence. In addition to standard health and safety obligations on the shoulders of the employer rest so additional tasks resulting from art. 222 § 1 K. P. The article discusses the detailed rules of conduct set out in the Regulation of the Minister of Health of 24 July 2012. On chemical substances and their mixtures, factors or technological processes with carcinogenic or mutagenic in the work environment. Order to comply the obligations imposed on the employer is taking proper care of the health of workers occupationally exposed to carcinogens and take preventive measures widely understood.
Źródło:
Prace Naukowe Akademii im. Jana Długosza w Częstochowie. Technika, Informatyka, Inżynieria Bezpieczeństwa; 2016, T. 4; 77-85
2300-5343
Pojawia się w:
Prace Naukowe Akademii im. Jana Długosza w Częstochowie. Technika, Informatyka, Inżynieria Bezpieczeństwa
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of Index Models for Assessing Freshwater Microplastics Pollution
Autorzy:
Enyoh, Christian Ebere
Verla, Andrew Wirnkor
Rakib, Md. Refat Jahan
Powiązania:
https://bibliotekanauki.pl/articles/1840784.pdf
Data publikacji:
2021
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Carcinogenic
Estimated daily intake
Health risks
Modeling
Plastic pollution
Opis:
Due to the differences in reporting units and methodology on microplastics (MP) studies, there has been some difficulty in comparing results across studies. In this study, we presented index models that can be address this issue. Index models for pollution and health risks assessment was applied to MP data obtained from rivers in Nwangele L.G.A. Models such as microplastics contamination factor (MPCF), microplastics pollution load index (MPPLI), Microplastics polymer risk indices (Hi) and pollution risk index (MPR) for pollution and contamination assessment. Health risk models such estimated daily intake (EDI) and microplastic carcinogenic risks (MPCR) through oral and dermal pathway were also presented and applied. Results showed that there is no direct correlation of MP abundance with MPR. However, Hi correlated but with MPR. Increased MPs pollution risks and levels were extensively subject to the presence of harmful MPs polymers, just as the high MPs pollution loads index (MPPLI). The index models enabled easy comparison of MP pollution of the different rivers and provided concise information on the status of MPs in the rivers.
Źródło:
World News of Natural Sciences; 2021, 38; 37-48
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of Pt internal catalyst on relative carcinogenic coefficient (RCC) of polycyclic aromatic hydrocarbons (PAHs) emitted from diesel engine
Autorzy:
Janicka, A.
Walkowiak, W.
Szczepaniak, W.
Powiązania:
https://bibliotekanauki.pl/articles/247594.pdf
Data publikacji:
2008
Wydawca:
Instytut Techniczny Wojsk Lotniczych
Tematy:
internal catalyst
polycyclic aromatic hydrocarbons
relative carcinogenic coefficient
diesel engine
Opis:
One of the main anthropogenic sources of PAHs emission is motorization, especially compression ignition engines. The researches of International Agency for Research on Cancer (IARC) proved that some compounds from polycyclic aromatic hydrocarbons group are toxic for live organisms and cause damages of adrenal glands, lymphatic, circulation and respiratory systems. Because of carcinogenic properties and common occurrence in human environment benzo(a)pirene has been accepted as polycyclic aromatic hydrocarbons indicator. In relation to benzo(a)pirene, Nisbet and LaGoy determined relative carcinogenic coefficients (RCC) for individual polycyclic aromatic hydrocarbons. The paper presents results of analysis of PAHs RCC emitted from SB3.1 self-ignition engine with Pt active coating application inside. The catalyst was applied on engine valves surface. Zirconium ceramic was chosen as a coating for catalyst application (also because of its thermo-isolating properties). Because of unstable parameters of self-ignition engine work (pressure and temperature jumps), PAHs were extracted from two phases: gas phase and solid phase (particle matter - PM). A chromatographic method of polycyclic aromatic hydrocarbons identification and analysis, because of their low level of concentration in exhaust gases, needed to be supported by sample purification and enrichment stages. It has been found that implementation of catalytic coating on valves of the engine causes decrease of polycyclic aromatic hydrocarbons concentration in exhaust gases, what results in decrease (in most cases) of the sum of relative carcinogenic coefficient of polycyclic aromatic hydrocarbons.
Źródło:
Journal of KONES; 2008, 15, 3; 209-213
1231-4005
2354-0133
Pojawia się w:
Journal of KONES
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
THE EFFECT OF METRONIDAZOLE ON THE VIABILITY OF CAL-27 TONGUE CANCER CELLS.
Autorzy:
Tołoczko-Iwaniuk, Natalia
Dziemiańczyk-Pakieła, Dorota
Celińska-Janowicz, Katarzyna
Drągowski, Paweł
Groth, Dawid
Reszeć, Joanna
Car, Halina
Borys, Jan
Miltyk, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/895561.pdf
Data publikacji:
2018-10-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
metronidazole
oral cancer
CAL-27
carcinogenic potential of the drugs
Opis:
Metronidazole belongs to the most commonly prescribed medications for bacterial and parasitic infections worldwide. It is also used in perioperative prevention prior to bowel, and head and neck surgeries. Despite the fact that the World Health Organization has placed it on its List of Essential Medicines, it is considered potentially carcinogenic. A great number of research studies have been conducted to clarify this issue, but results are inconclusive. None of the studies focused on the influence of metronidazole on oral cancer development. The aim of our study was to evaluate the impact of metronidazole on the viability of tongue cancer cells. The research was conducted on the tongue squamous cell carcinoma cell line (CAL-27). Metronidazole dissolved in growth medium was applied to the cell culture at concentrations: 1, 10, 50, 100μg/mL. Toxicity of the drug was evaluated by MTT assay and the [3H]-thymidine incorporation test. The MTT test revealed a significant increase in cell viability under the influence of metronidazole after 24h, at the highest concentration of the drug (100μg/mL), but had no impact on cell viability at other concentrations and after 48h and 72h. The results of the [3H]-thymidine incorporation test did not show significant results. Summarizing, metronidazole stimulates the viability of tongue squamous cell carcinoma cells according to its concentration and the time of incubation (results significant at the concentration 100μg/mL, after 24 hours of incubation).
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 5; 1233-1240
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pollution and health risk assessment of water quality: a case study in Mohammedia prefecture in Morocco
Autorzy:
El morabet, R.
Berhazi, L.
Khan, R. A.
Bouhafa, S.
Khan, N. A.
Hakh, T.
Romaniv, A.
Powiązania:
https://bibliotekanauki.pl/articles/2055750.pdf
Data publikacji:
2022
Wydawca:
Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
Tematy:
water quality assessment
water pollution index
ecological risk
non-carcinogenic risk
carcinogenic risk
ocena jakości wody
wskaźnik zanieczyszczenia wody
ryzyko ekologiczne
ryzyko nierakotwórcze
ryzyko rakotwórcze
Opis:
Purpose: Water is vital for the sustenance of every life form. Urbanization, growing population and industrial development has led to exploitation of water resources globally. This study assesses quality of water resources of Mohammedia prefecture. Design/methodology/approach: The water quality analysis was carried out based on physio-chemical and heavy metal concentrations. The physio-chemical analysis comprised of status of concentration, overall quality and water pollution index evaluation. The heavy metal evaluation consisted of Ecological Risk Index, non-carcinogenic risk and carcinogenic risk assessment. Findings: The landfill near Ben Nfifikh River reported insignificant (WPI<1) – low level of pollution (>1≤1.5) for surface and groundwater points. However, the groundwater for Zenata region was found to pose both carcinogenic (CRt > 0.0001, range 0.4-35.31) and non-carcinogenic risks (HQ>1, range 6 -34) of higher degree rendering it unfit for human consumption. Hence, this study concludes that groundwater resources should not as water supply; instead, Oud El Maleh River can serve as surface water source for meeting requirements of Zenata region. Research limitations/implications: The data obtained can be categorized as landfill area near river Nfifikh and landfill area near river El Maleh. Both areas have been investigated for groundwater and surface water quality assessment. Practical implications: This study demonstrates the need to study the characteristics of groundwater (depth, flow rate, water renewal, etc.) before arranging a waste dump. This problem is especially relevant for arid countries, since residents experience a shortage of water, as well as a lack of rainfall provides a weak renewal of groundwater, which can contribute to the accumulation of a higher concentration of carcinogens in groundwater and provide a high risk to public health. If policymakers in arid countries and decision-makers have effective water quality maps, then the country can be more efficiently managed water resources without risking the population. Originality/value: The current study is planned as a multi-stage, each of which is supposed to conduct field studies of groundwater and surface water quality with appropriate parameters, analysis of institutional reports and related scientific studies in order to create an effective water quality map for rational water use.
Źródło:
Journal of Achievements in Materials and Manufacturing Engineering; 2022, 110, 2; 67--85
1734-8412
Pojawia się w:
Journal of Achievements in Materials and Manufacturing Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kobalt w środowisku pracy – zagrożenia i oznaczanie
Autorzy:
Gawęda, E.
Powiązania:
https://bibliotekanauki.pl/articles/179142.pdf
Data publikacji:
2000
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
kobalt
substancje niebezpieczne
substancje rakotwórcze
NDS
cobalt
dangerous substances
carcinogenic substances
Źródło:
Bezpieczeństwo Pracy : nauka i praktyka; 2000, 11; 21-23
0137-7043
Pojawia się w:
Bezpieczeństwo Pracy : nauka i praktyka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Klasyfikacje chemicznych czynników rakotwórczych – przegląd
Classifications of chemical carcinogenic factors – a review
Autorzy:
Czerczak, S.
Powiązania:
https://bibliotekanauki.pl/articles/179895.pdf
Data publikacji:
2004
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
czynniki rakotwórcze
czynniki chemiczne
klasyfikacje czynników rakotwórczych
carcinogenic factors
chemical agents
Opis:
W artykule omówiono kryteria oceny działania rakotwórczego przyjęte przez Międzynarodową Agencję Badań nad Rakiem (IARC) oraz klasyfikacje czynników rakotwórczych przyjęte w USA, Niemczech, Unii Europejskiej i w Polsce.
The article discusses criteria for the evaluation of carcinogenic activity, adopted by the International Agency for Research on Cancer, as well as classifications of carcinogenic factors adopted by the USA, Germany, the European Union and Poland.
Źródło:
Bezpieczeństwo Pracy : nauka i praktyka; 2004, 1; 9-14
0137-7043
Pojawia się w:
Bezpieczeństwo Pracy : nauka i praktyka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cytostatics as hazardous chemicals in healthcare workers’ environment
Autorzy:
Pałaszewska-Tkacz, Anna
Czerczak, Sławomir
Konieczko, Katarzyna
Kupczewska-Dobecka, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/2161986.pdf
Data publikacji:
2019-04-03
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
carcinogenic agents
safety data sheets
healthcare workers
OEL
cytostatic
occupational exposure limits
Opis:
Cytostatics not only induce significant side-effects in patients treated oncologically but also pose a threat to the health of occupationally exposed healthcare workers: pharmacists, physicians, nurses and other personnel. Since the 1970s numerous reports from various countries have documented the contamination of working areas with cytostatics and the presence of drugs/metabolites in the urine or blood of healthcare employees, which directly indicates the occurrence of occupational exposure to these drugs. In Poland the significant scale of occupational exposure to cytostatics is also confirmed by the data collected in the central register of occupational carcinogens/mutagens kept by the Nofer Institute of Occupational Medicine. The assessment of occupational exposure to cytostatics and health risks constitutes employers’ obligation. Unfortunately, the assessment of occupational risk resulting from exposure to cytostatics raises a number of concerns. Provisions governing the problem of workers’ health protection are not unequivocal because they derive from a variety of law areas, especially in a matter of hazard classification and safety data sheets for cytostatics. Moreover, no legally binding occupational exposure limits have been set for cytostatics or their active compounds, and analytical methods for these substances airborne and biological concentrations are lacking. Consequently, the correct assessment of occupational exposure to cytostatics, the evaluation of health hazards and the development of the proper preventive strategy appear difficult. The authors of this article described and discussed the amendments to the European provisions concerning chemicals in the light of employers’ obligations in the field of employees’ heath protection against the consequences of exposure to cytostatics. Some modifications aimed at a more effective health protection of workers occupationally exposed to cytostatics were also proposed. Int J Occup Med Environ Health. 2019;32(2):141–59
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2019, 32, 2; 141-159
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czynniki rakotwórcze i mutagenne w świetle ustawodawstwa polskiego i Unii Europejskiej
Carcinogenic and mutagenic agents in Polish and UE legal regulations
Autorzy:
Skowroń, J.
Powiązania:
https://bibliotekanauki.pl/articles/138368.pdf
Data publikacji:
2007
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
czynniki rakotwórcze i mutagenne
normatywy higieniczne
carcinogenic and mutagenic agents
hygienic standards
legislation
Opis:
Omówiono uregulowania prawne dotyczące czynników rakotwórczych i mutagennych przyjęte w Polsce, a także zasady oceny narażenia i ryzyka związanego z występowaniem substancji rakotwórczych na stanowiskach pracy oraz ochrony zdrowia pracowników narażonych na ich działanie. Przedstawiono również aktualne dane o zawodowych chorobach nowotworowych, ocenie narażenia na substancje ropopochodne i węglopochodne oraz dane statystyczne na ten temat. Omówiono także uregulowania prawne dotyczące czynników rakotwórczych i mutagennych w państwach Unii Europejskiej. Carcinogenic and mutagenic agents in Polish and UE legal regulations.
The article presents Polish regulations for carcinogenic and mutagenic agents, the evaluation of carcinogenic/ mutagenic risks and prevention of workers’ health occupationally exposed to them. Information about occupational cancer, data collected on the exposure to carcinogenic or mutagenic hydrocarbons or substances derived from coal and statistical data is also presented. Moreover, some information about UE regulations in this area is given.
Źródło:
Podstawy i Metody Oceny Środowiska Pracy; 2007, 4 (54); 5-43
1231-868X
Pojawia się w:
Podstawy i Metody Oceny Środowiska Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Do we know PM1 in Poland inside out?
Autorzy:
Rogula-Kozłowska, Wioletta
Powiązania:
https://bibliotekanauki.pl/articles/28407390.pdf
Data publikacji:
2023
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
PM1
carcinogenic compounds
particulate matter
health effect
związki rakotwórcze
cząstki stałe
efekt zdrowotny
Opis:
The paper provides a concise review of key publications on particulate matter of aerodynamic diameter below 1 μm (PM1) having been published in Poland in the years 2007–2022. Data and conclusions related to the study of concentrations, chemical composition, and content of selected toxic and carcinogenic compounds in PM1 as well as methods and conclusions on the assessment of the origin of PM1 in various regions of Poland have been tabulated. The conclusions of this review attempt to outline the directions of further research that could prove crucial in obtaining information and filling the identified gaps in knowledge about PM1 in Poland. While this work may be theoretical, it can serve as a valuable and compact source material for research groups, organizations supervising and financing research, as well as those responsible for assessing air quality and mitigating negative health effects related to air quality.
Źródło:
Environment Protection Engineering; 2023, 49, 4; 5--27
0324-8828
Pojawia się w:
Environment Protection Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł

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