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    Wyświetlanie 1-6 z 6
    Tytuł:
    A new method of cardiac sympathetic index estimation using a 1D-convolutional neural network
    Autorzy:
    Kołodziej, Marcin
    Majkowski, Andrzej
    Tarnowski, Paweł
    Rak, Remigiusz Jan
    Rysz, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/2090741.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    epilepsy
    seizure detection
    seizure prediction
    convolutional neural network
    deep learning
    ECG
    HRV
    cardiac sympathetic index
    padaczka
    wykrywanie napadu
    przewidywanie napadu
    splotowa sieć neuronowa
    głęboka nauka
    technika deep learning
    EKG
    wskaźnik współczulny serca
    Opis:
    Epilepsy is a neurological disorder that causes seizures of many different types. The article presents an analysis of heart rate variability (HRV) for epileptic seizure prediction. Considering that HRV is nonstationary, our research focused on the quantitative analysis of a Poincare plot feature, i.e. cardiac sympathetic index (CSI). It is reported that the CSI value increases before the epileptic seizure. An algorithm using a 1D-convolutional neural network (1D-CNN) was proposed for CSI estimation. The usability of this method was checked for 40 epilepsy patients. Our algorithm was compared with the method proposed by Toichi et al. The mean squared error (MSE) for testing data was 0.046 and the mean absolute percentage error (MAPE) amounted to 0.097. The 1D-CNN algorithm was also compared with regression methods. For this purpose, a classical type of neural network (MLP), as well as linear regression and SVM regression, were tested. In the study, typical artifacts occurring in ECG signals before and during an epileptic seizure were simulated. The proposed 1D-CNN algorithm estimates CSI well and is resistant to noise and artifacts in the ECG signal.
    Źródło:
    Bulletin of the Polish Academy of Sciences. Technical Sciences; 2021, 69, 3; e136921, 1--9
    0239-7528
    Pojawia się w:
    Bulletin of the Polish Academy of Sciences. Technical Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A new method of cardiac sympathetic index estimation using a 1D-convolutional neural network
    Autorzy:
    Kołodziej, Marcin
    Majkowski, Andrzej
    Tarnowski, Paweł
    Rak, Remigiusz Jan
    Rysz, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/2173565.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    epilepsy
    seizure detection
    seizure prediction
    convolutional neural network
    deep learning
    ECG
    HRV
    cardiac sympathetic index
    padaczka
    wykrywanie napadu
    przewidywanie napadu
    splotowa sieć neuronowa
    głęboka nauka
    technika deep learning
    EKG
    wskaźnik współczulny serca
    Opis:
    Epilepsy is a neurological disorder that causes seizures of many different types. The article presents an analysis of heart rate variability (HRV) for epileptic seizure prediction. Considering that HRV is nonstationary, our research focused on the quantitative analysis of a Poincare plot feature, i.e. cardiac sympathetic index (CSI). It is reported that the CSI value increases before the epileptic seizure. An algorithm using a 1D-convolutional neural network (1D-CNN) was proposed for CSI estimation. The usability of this method was checked for 40 epilepsy patients. Our algorithm was compared with the method proposed by Toichi et al. The mean squared error (MSE) for testing data was 0.046 and the mean absolute percentage error (MAPE) amounted to 0.097. The 1D-CNN algorithm was also compared with regression methods. For this purpose, a classical type of neural network (MLP), as well as linear regression and SVM regression, were tested. In the study, typical artifacts occurring in ECG signals before and during an epileptic seizure were simulated. The proposed 1D-CNN algorithm estimates CSI well and is resistant to noise and artifacts in the ECG signal.
    Źródło:
    Bulletin of the Polish Academy of Sciences. Technical Sciences; 2021, 69, 3; art. no. e136921
    0239-7528
    Pojawia się w:
    Bulletin of the Polish Academy of Sciences. Technical Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Regulation of subcellular localization of muscle FBPase in cardiomyocytes. The decisive role of calcium ions
    Autorzy:
    Majkowski, Michal
    Wypych, Dorota
    Pomorski, Pawel
    Dzugaj, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/1042732.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cardiomyocytes
    Z-line
    insulin
    calcium
    intercalated disc
    muscle FBPase
    Opis:
    Glyconeogenesis, the synthesis of glycogen from carbohydrate precursors like lactate, seems to be an important pathway participating in replenishing glycogen in cardiomyocytes. Fructose-1,6-bisphosphatase (FBPase), an indispensible enzyme of glyconeogenesis, has been found in cardiomyocytes on the Z-line, in the nuclei and in the intercalated discs. Glyconeogenesis may proceed only when FBPase accumulates on the Z-line. Searching for the mechanism of a FBPase regulation we investigated the effects of the calcium ionophore A23187, a muscle relaxant dantrolene, glucagon, insulin and medium without glucose on the subcellular localization of this enzyme in primary culture of neonatal rat cardiomyocytes. Immunofluorescence was used for protein localization and the intracellular calcium concentration was measured with Fura. We found that the concentration of calcium ions was the decisive factor determining the localization of muscle FBPase on the Z-line. Calcium ions had no effect on the localization of the enzyme in the intercalated discs or in the nuclei, but accumulation of FBPase in the nuclei was induced by insulin.
    Źródło:
    Acta Biochimica Polonica; 2010, 57, 4; 597-605
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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