Autor: Jasiński, Marek - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Modeling of the influence of elevated temperature on oxygen distribution in soft tissue
Autorzy:: Jasiński, Marek
Zadoń, Maria
Powiązania:: https://bibliotekanauki.pl/articles/38910037.pdf
Data publikacji:: 2023
Wydawca:: Instytut Podstawowych Problemów Techniki PAN
Tematy:: bioheat transfer
tissue thermal damage
oxygen transport
Krogh cylinder
oxyhemoglobin dissociation curve
finite difference method
shooting method
sensitivity analysis
Opis:: The purpose of the study was to analyze the combined model of bioheat transfer and oxygen distribution in tissue during exposition to the external heat impulse. The effect of temperature and thermal damage to the tissue on the values of its thermophysical parameters was taken into account. The variable value of the perfusion coefficient affects the blood velocity in the capillary and thus the distribution of the partial oxygen pressure in the tissue. Various models of the oxygen dissociation curves were also considered and a sensitivity analysis was performed for the parameters of the oxygen distribution model. In the numerical realization stage, the finite difference method and the shooting method were used.
Źródło:: Engineering Transactions; 2023, 71, 3; 287-306
0867-888X
Pojawia się w:: Engineering Transactions
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Modeling of photochemical and photothermal effects in soft tissue subjected to laser irradiation
Autorzy:: Jasiński, Marek
Zadoń, Maria
Powiązania:: https://bibliotekanauki.pl/articles/38706609.pdf
Data publikacji:: 2024
Wydawca:: Instytut Podstawowych Problemów Techniki PAN
Tematy:: bioheat transfer
optical diffusion equation
photodynamic therapy
boundary element method
finite difference method
transfer biociepła
równanie dyfuzji optycznej
terapia fotodynamiczna
metoda elementów brzegowych
metoda różnic skończonych
Opis:: The purpose of this study is to analyze the phenomena that occur in biological tissueduring photodynamic therapy (PDT). Under the influence of the laser, triplet oxygen istransformed into singlet oxygen, which is cytotoxic to cancer tissue. The impact of thelaser on the tissue may also be accompanied by changes in the thermophysical parameters,e.g., perfusion, which can affect the supply of oxygen to the tissue and, consequently,the outcome of the therapy. The proposed model uses the optical diffusion equation,the Pennes bioheat transfer equation, and reactions equations for PDT. The connectionbetween bioheat transfer and PDT models is taken into account through the respectiverelationships between perfusion rate, capillary blood velocity, and the maximum oxygensupply rate. Furthermore, a method is proposed to model abnormal vascular patterns inthe tumor subdomain. The boundary element method and the finite difference methodwere used in the numerical implementation stage.
Źródło:: Computer Assisted Methods in Engineering and Science; 2024, 31, 1; 29-50
2299-3649
Pojawia się w:: Computer Assisted Methods in Engineering and Science
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Mathematical modeling of the phenomena that occur in a biological tissue containing photosensitizer
Autorzy:: Jasiński, Marek
Zadoń, Maria
Powiązania:: https://bibliotekanauki.pl/articles/2202041.pdf
Data publikacji:: 2022
Wydawca:: Politechnika Częstochowska. Wydawnictwo Politechniki Częstochowskiej
Tematy:: bioheat transfer
optical diffusion equation
photodynamic therapy
boundary element method
finite difference method
przepływ ciepła
równanie dyfuzji optycznej
terapia fotodynamiczna
metoda elementów brzegowych
metoda różnic skończonych
Opis:: The aim of the study is to analyze photothermal and photochemical phenomena that occur during photodynamic therapy (PDT). In this type of therapy, under the influence of the laser, reactions take place related to the transformation of triplet oxygen form into its singlet form which is cytotoxic to the tissue. The increases in temperature resulting from the laser-tissue interaction during PDT are not big; however, they can lead to changes in tissue perfusion, which can affect oxygen delivery to the tissue. The proposed model uses optical diffusion equation, Pennes bioheat transfer equation, and reactions equations for PDT. The main findings of the analysis show the impact of temperature on the value of the perfusion coefficient and triplet oxygen distributions at the end of the treatment procedure.
Źródło:: Journal of Applied Mathematics and Computational Mechanics; 2022, 21, 4; 40--51
2299-9965
Pojawia się w:: Journal of Applied Mathematics and Computational Mechanics
Dostawca treści:: Biblioteka Nauki

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