- Tytuł:
- Paramagnetic Centers in DOPA-Melanin-Dihydrostreptomycin Complexes
- Autorzy:
-
Buszman, E.
Pilawa, B.
Zdybel, M.
Wrześniok, D.
Grzegorczyk, A.
Wilczok, T. - Powiązania:
- https://bibliotekanauki.pl/articles/2043624.pdf
- Data publikacji:
- 2005-08
- Wydawca:
- Polska Akademia Nauk. Instytut Fizyki PAN
- Tematy:
-
61.66.Hq
76.30.Rn - Opis:
- DOPA-melanin-dihydrostreptomycin complexes with drug concentrations 1×10$\text{}^{-4}$-1×10$\text{}^{-2}$ M were examined by the use of electron paramagnetic resonance spectroscopy at X-band (9.3 GHz). Dihydrostreptomycin was chosen for studies, because this aminoglycoside antibiotic causes strong toxic effects in organism. It was stated that dihydrostreptomycin generates o-semiquinone free radicals with g=2.0038 in melanin. Free radicals formation increases with increase in the antibiotic concentration. Changes of EPR lines with microwave powers pointed out that slow spin-lattice relaxation processes exist in DOPA-melanin and in its complexes with dihydrostreptomycin. The measured EPR lines were homogeneously broadened.
- Źródło:
-
Acta Physica Polonica A; 2005, 108, 2; 353-356
0587-4246
1898-794X - Pojawia się w:
- Acta Physica Polonica A
- Dostawca treści:
- Biblioteka Nauki
Artykuł