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Wyświetlanie 1-3 z 3
Tytuł:
Analysis and experiments of embedded gripping mechanism used in large-scale tools holding up pile foundation in ocean
Autorzy:
Wang, Zhuo
Zhang, Bo
Wang, Tao
Powiązania:
https://bibliotekanauki.pl/articles/259156.pdf
Data publikacji:
2019
Wydawca:
Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
Tematy:
pile foundation
gripping
embedded mechanism
embedded depth
upending gripper
Opis:
With the rapid development of the marine economy and continuous improvement of the industry, the scale of the offshore engineering is increasing. This raises interest in studying, theoretically and experimentally, gripping and bearing mechanisms for large-scale holding and lifting tools used in foundation pile installations. In this paper, the embedded gripping mechanism is studied based on the theory of elastic-plastic mechanics. The embedded and bearing performance of the tooth is simulated and the influence factors are studied. In addition, the device used in the simplified embedded experiment on the tooth of the embedded block is designed. The relationship between embedded depth, load, and tooth profile angle is identified and validated. Meanwhile, the embedded performance of linear and ring type teeth is compared experimentally in order to select the suitable type of tooth for various situations. This comparison makes the basis for designing an upending gripper for the marine pile foundation, which can realize the operation of holding the pile to prevent its falling.
Źródło:
Polish Maritime Research; 2019, 3; 15-21
1233-2585
Pojawia się w:
Polish Maritime Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
NEW BETULIN NITRATES: SYNTHESIS, CYTOTOXIC ACTIVITY AND MOLECULAR DOCKING EVALUATION
Autorzy:
Feng, GaiLi
Wang, Tao
Zhang, Rong
Luo, Jin
Xiao, MinJie
He, BaoEn
Liu, YongQian
Wu, JunXiao
Powiązania:
https://bibliotekanauki.pl/articles/895411.pdf
Data publikacji:
2018-10-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Molecular docking
anti-tumor
Betulin nitrates
NO donors
Opis:
Betulin and its derivatives have been reported to affect several key genes of cell-cycle regulators. However, their specific targets haven’t yet been discovered. As an important cell cycle regulator, Cyclin-dependent kinase-2 (CDK2) has become a potential target for cancer therapy. Here we describe the design, synthesis and antitumor activities in vitro of eleven new betulin nitrates. The results revealed that compound (20) possesses potent antitumor activity against MCF-7 cell lines (IC50 < 10 μM). In order to investigate potential protein target, betulin nitrates were subjected to docking studies with CDK2. Compound (20) showed very good binding affinity for CDK2 via hydrogen bonding interactions. Thus, the CDK2 inhibitory potential could make compound (20) possible candidate as antitumor agent.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 5; 1135-1145
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of Annealing Treatment on Deep Drawing Behavior of Q235 Carbon Steel /410/304 Stainless Steels Three-Layer Composite Plate
Autorzy:
Lv, Zehua
Zhang, Zhixiong
Han, Jianchao
Wang, Tao
Powiązania:
https://bibliotekanauki.pl/articles/2106574.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
composite plate
deep drawing
annealing
microstructure
Opis:
Effect of annealing treatment on deep drawing behavior of hot-rolled Q235 carbon steel/410/304 stainless steel three-layer composite plate was investigated. Deep drawability of the unannealed composite plates exhibits a sharp difference for various contact surfaces with the die. The limit drawing ratio (LDR) of the composite plate with the carbon steel contacting the die is 1.75, while it is 1.83 with the stainless steel contacting the die due to the different mechanical responses to the tensile stress at the corner of the die. After annealing at 900°C for 2 h, however, the deep drawabilities of the composite plates both for various contact surfaces with the die are significantly improved and becomes almost identical, which are attributed to the stress relief, the enhanced ductility and the improved interface bonding strength of the hot-rolled component plates during annealing.
Źródło:
Archives of Metallurgy and Materials; 2022, 67, 2; 421--433
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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