Autor: Węgrzyn, Anna - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Combined effect of stringent or relaxed response, temperature and rom function on the replication of pUC plasmids in Escherichia coli
Autorzy:: Herman, Anna
Węgrzyn, Alicja
Węgrzyn, Grzegorz
Powiązania:: https://bibliotekanauki.pl/articles/1045341.pdf
Data publikacji:: 1994
Wydawca:: Polskie Towarzystwo Biochemiczne
Źródło:: Acta Biochimica Polonica; 1994, 41, 2; 122-124
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Molecular factors involved in the development of diabetic foot syndrome
Autorzy:: Bruhn-Olszewska, Bożena
Korzon-Burakowska, Anna
Gabig-Cimińska, Magdalena
Olszewski, Paweł
Węgrzyn, Alicja
Jakóbkiewicz-Banecka, Joanna
Powiązania:: https://bibliotekanauki.pl/articles/1039639.pdf
Data publikacji:: 2012
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: Diabetic foot syndrome
molecular mechanisms
Charcot neuroartropathy
bone metabolism
Opis:: Diabetes is one of the major challenges of modern medicine, as it is considered a global epidemic of the XXI century. The disease often leads to the development of serious, health threatening complications. Diabetic foot syndrome is a characteristic set of anatomical and molecular changes. At the macroscopic level, major symptoms are neuropathy, ischemia and chronic ulceration of the lower limb. In every third patient, the neuropathy develops into Charcot neuroarthropathy characterized by bone and joints deformation. Interestingly, all these complications are a result of impaired healing processes and are characteristic for diabetes. The specificity of these symptoms comes from impaired molecular mechanisms observed in type 1 and type 2 diabetes. Decreased wound and fracture healing reflect gene expression, cellular response, cell functioning and general metabolism. Here we present a comprehensive literature update on the molecular factors contributing to diabetic foot syndrome.
Źródło:: Acta Biochimica Polonica; 2012, 59, 4; 507-513
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Transforming growth factor β1 protein and mRNA levels in inflammatory bowel diseases: towards solving the contradictions by longitudinal assessment of the protein and mRNA amounts
Autorzy:: Liberek, Anna
Kmieć, Zbigniew
Wierzbicki, Piotr
Jakóbkiewicz-Banecka, Joanna
Liberek, Tomasz
Łuczak, Grażyna
Plata-Nazar, Katarzyna
Słomińska-Frączek, Magdalena
Kaszubowska, Lucyna
Gabig-Cimińska, Magdalena
Węgrzyn, Alicja
Powiązania:: https://bibliotekanauki.pl/articles/1039466.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: Crohn's disease
ulcerative colitis
Transforming Growth Factor-β1
longitudinal assessment of TGF-β1 level
Opis:: Previously published studies on levels of the transforming growth factor-β1 (TGF-β1) protein and mRNA of the corresponding gene in patients suffering from inflammatory bowel diseases (IBD) gave varying results, leading to contradictory conclusions. To solve the contradictions, we aimed to assess longitudinally TGF-β1 protein and mRNA levels at different stages of the disease in children suffering from IBD. The study group consisted of 19 pediatric patients with IBD at the age between 3.5 and 18.4 years. The control group consisted of 42 children aged between 2.0 and 18.0 years. The plasma TGF-β1 concentration was measured with ELISA. mRNA levels of the TGF-β1 gene isolated from samples of the intestinal tissue were assessed by reverse transcription and real-time PCR. Levels of TGF-β1 protein in plasma and corresponding mRNA in intestinal tissue were significantly higher in IBD patients than in controls. TGF-β1 and corresponding transcripts were also more abundant in plasma and intestinal tissue, respectively, in patients at the active stage of the disease than during remission. In every single IBD patient, plasma TGF-β1 level and mRNA level in intestinal tissue was higher at the active stage of the disease than during remission. Levels of TGF-β1 and corresponding mRNA are elevated during the active stage of IBD but not during the remission. Longitudinal assessment of this cytokine in a single patient may help to monitor the clinical course of IBD.
Źródło:: Acta Biochimica Polonica; 2013, 60, 4; 683-688
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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