- Tytuł:
-
Blood leucocyte responses in rats vaccinated with cDNA encoding glutathione-s-transferase of Fasciola hepatica
REAKCJA LEUKOCYTÓW KRWI SZCZURÓW SZCZEPIONYCH cDNA TRANSFERAZY s-GLUTATIONOWEJ FASCIOLA HEPATICA - Autorzy:
-
Wędrychowicz, H.
Jedlina-Panasiuk, L.
Szymański, P.
Bieńkowska-Szewczyk, K. - Powiązania:
- https://bibliotekanauki.pl/articles/2148264.pdf
- Data publikacji:
- 2001
- Wydawca:
- Polskie Towarzystwo Parazytologiczne
- Tematy:
-
glutathione s-transferase
blood
Fasciola hepatica
leucocyte level
vaccinated rat
cDNA
rat
leucocyte - Opis:
- Changes in blood leucocyte levels were investigated in Spraque-Dowley rats vaccinated with cDNA or protein of glutathione S-transferase (GST) of F. hepatica and subsequently challenged with metacercariae of the liver fluke. The analysis of the leucocyte responses measured in vaccinated rats suggests that the form of antigen used for vaccination intluenced dynamics of white blood cell response to the fluke infection. The most clear differences were observed in neutrophil and eosinophil levels. The weakest reaction of these cells to the challenge infection was observed in rats vaccinated twice with cDNA. In contrast, in rats which received the first antigen dose as cDNA and the second vaccination with GST protein, both neutrophil and eosinophil responses were much higher, especially at 5 and 9 WAI.
- Źródło:
-
Wiadomości Parazytologiczne; 2001, 47, 4; 551-557
0043-5163 - Pojawia się w:
- Wiadomości Parazytologiczne
- Dostawca treści:
- Biblioteka Nauki
Artykuł