- Tytuł:
- The influence of adriamycin on the CD4 and CD8 cells in the course of trichinellosis in mice
- Autorzy:
-
Karmanska, K
Houszka, M.
Mista, D.
Stefaniak, E. - Powiązania:
- https://bibliotekanauki.pl/articles/837229.pdf
- Data publikacji:
- 1994
- Wydawca:
- Polskie Towarzystwo Parazytologiczne
- Tematy:
-
parasite
mouse
mice
cell
trichinellosis
adriamycin
histopathology - Opis:
- The effect of adriamycin on the behaviour of CD4⁺ and CD8⁺ cells in the course of trichinellosis in mice has been studied. The animals infected with 200 larvae per mouse were administered intraperitoneally adriamycin (Adriblastin from Farmitalia) at 1st and 28th day post infection (dpi), in a dosis of 0.2 mg. The mice were killed weakly for 6 weeks and then at the 60th dpi. The examinations were made on histologic sections from the spleen, mesenteric lymph node, jejunum and masseter muscle using immunofluorescent and immunoenzymatic methods with monoclonal antibody. The mice receiving adriamycin exhibited more CD8⁺ cells in the intestinal mucosa and by the end of the experiment also in the muscles in comparison with the control animals, which, however, did not affect the course of the infection.
- Źródło:
-
Annals of Parasitology; 1994, 40, 4
0043-5163 - Pojawia się w:
- Annals of Parasitology
- Dostawca treści:
- Biblioteka Nauki
Artykuł