Autor: Rzeszotarska, Anna - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-(Z)-dehydropheny-alanine.
Autorzy:: Siodłak, Dawid
Broda, Małgorzata
Rzeszotarska, Barbara
Kozioł, Anna
Dybała, Izabela
Powiązania:: https://bibliotekanauki.pl/articles/1044080.pdf
Data publikacji:: 2001
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: alanine and phenylalanine derivatives
N',N'-dimethylamides
X-ray crystallography
α,β-dehydroamino acids
theoretical calculations
Opis:: Conformational preferences of Ac-ΔAla-NMe2 and Ac-(Z)-ΔPhe-NMe2 were studied and compared with those of their monomethyl counterparts as well as with those of their saturated analogues. X-Ray data and energy calculations revealed a highly conservative conformation of the dehydro dimethylamides, which is located in a high-energy region of the Ramachandran map.
Źródło:: Acta Biochimica Polonica; 2001, 48, 4; 1179-1183
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 2.

Tytuł:: Conformational investigation of α,β-dehydropeptides. XIII. Conformational properties of N-acetyl-α,β-dehydrovaline N',N'-dimethylamide.
Autorzy:: Siodłak, Dawid
Rzeszotarska, Barbara
Broda, Małgorzata
Kozioł, Anna
Kołodziejczyk, Edyta
Powiązania:: https://bibliotekanauki.pl/articles/1043332.pdf
Data publikacji:: 2004
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: ab initio/DFT calculations
N',N'-dimethylamides
X-ray crystallography
α,β-dehydroamino acids
peptide design
valine derivative
Opis:: The crystal structure of Ac-ΔVal-NMe2 (ΔVal = α,β-dehydrovaline) was determined by X-ray crystallography. The found angles φ = -60° and ψ = 125° correspond exactly to the respective values of the (i + 1)th residue in idealised β-turn II/VIa. Ab initio/DFT studies revealed that the molecule adopts the angle ψ restricted only to about |130°| and very readily attains the angle φ = about -50°. This is in line with its solid-state conformation. Taken together, these data suggest that the ΔVal residue combined with a C-terminal tertiary amide is a good candidate at the (i + 1)th position in a type II/VIa β-turn.
Źródło:: Acta Biochimica Polonica; 2004, 51, 1; 145-152
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

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