- Tytuł:
- Synthesis and antimicrobial activity of oxadiazole nucleus containing 2,5-substituted 1,3,4-oxadiazole derivatives
- Autorzy:
-
Gajera, Jayesh L
Sutariya, Jignesh K.
Rakesh Gothwal, Rakesh
Sharma, Vinay S.
Ram, Haresh
Godhaviya, Pankaj K. - Powiązania:
- https://bibliotekanauki.pl/articles/1839273.pdf
- Data publikacji:
- 2021
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
cyclohexanecarbohydrazide
antibacterial
antifungal
1,3,4-oxadiazole - Opis:
- In this study, we report the synthesis of 2,5-substituted 1,3,4-oxadiazole derivatives using condensation of cyclohexanecarbohydrazide derivatives and carbon disulfide. In present study, we have prepared total seven derivatives based on 1,3,4-oxadiazole core further functionalized with thiol moieties. The structures of synthesized compounds (C1-C9) were confirmed by the 1H NMR, and Mass spectrometry. These synthesized molecules were subjected to antibacterial and fungal activity against selected microbial and fungal strains. Some of derivatives showed good biological behaviour against gram positive and gram negative bacteria.
- Źródło:
-
World Scientific News; 2021, 162; 75-86
2392-2192 - Pojawia się w:
- World Scientific News
- Dostawca treści:
- Biblioteka Nauki
Artykuł