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    Wyświetlanie 1-2 z 2
    Tytuł:
    Large plexiform neurofibroma on right thigh of a farmer in the course of Recklinghausen disease - Case report
    Autorzy:
    Sompor, J.
    Prystupa, A.
    Wawrzycki, B.
    Wojciechowska, K.
    Kancik, E.
    Kurys-Denis, E.
    Ochal, A.
    Prystupa, T.
    Jojczuk, M.
    Kulesza, T.
    Antosz, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/3231.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    right thigh
    farmer
    human disease
    Recklinghausen's disease
    tumour
    neurofibromatosis
    Opis:
    A 59-year-old farmer was admitted to the Department of Trauma Surgery because of pain associated with the presence of a tumour on the side of the right thigh. The patient stated that his biggest problem was great difficulty in moving and handling agricultural machinery due to the aforementioned lesion. On physical examination, the patient presented with numerous cutaneous and subcutaneous neurofibromas, as well as one large plexiform neurofibroma. Diagnosis of Neurofibromatosis type 1 was established, based on National Institutes of Health diagnostic criteria. Moreover, molecular genetic testing found known pathogenic mutation p.Arg1769* in one of the alleles of NF1 gene (heterozygote), typical for Recklinghausen disease. The big plexiform neurofibroma in the patient was not operated on because of lung cancer.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Afamin and adropin in patients with alcohol-induced liver cirrhosis
    Autorzy:
    Prystupa, A.
    Kiciński, P.
    Luchowska-Kocot, D.
    Sak, J.
    Prystupa, T.
    Chen, K.-H.
    Chen, Y.-H.
    Panasiuk, L.
    Załuska, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081906.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    alcoholic liver cirrhosis
    Adropin
    Child-Pugh score
    afamin
    Opis:
    The aim of the study was to determine serum concentrations of afamin and adropin in patients with alcoholic liver cirrhosis and to define their correlation with the stage of disease. The study included 99 patients with alcoholic cirrhosis from the region of Lublin, (Eastern Poland). Liver cirrhosis was diagnosed based on clinical features, history of heavy alcohol consumption, laboratory tests and abdominal ultrasonography. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The serum afamin and adropin concentrations were determined using ELISA kits. The concentration of afamin was found to be significantly lower in patients with compensated alcoholic liver cirrhosis, i.e. P-Ch B (85.1±40.6 μg/ml) and P-Ch C (56.4±32.3 μg/ml) individuals, compared to the control group (135.9±43.6 μg/ml); p-value was <0.01 and <0.001, respectively. As far as adropin is concerned, a reverse relationship was demonstrated: the highest concentration was found in patients with P-Ch C (11.7±5.7 ng/ml) cirrhosis. Furthermore, the above concentration was significantly higher compared to patients with P-Ch A cirrhosis (7.2±2.8 ng/ml; p<0.05) and controls (7.5±2.6 ng/ml; p<0.05). The concentration of afamin decreases with the severity of alcoholic liver cirrhosis, which most likely results from impaired hepatic synthesis. Otherwise, the higher the stage of disease according to the Child-Pugh score, the higher the concentration of adropin.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 3; 527-531
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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