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    Wyświetlanie 1-4 z 4
    Tytuł:
    Oxidative stress-induced growth inhibitor 1 in alcohol-induced liver cirrhosis
    Autorzy:
    Sak, J.J.
    Prystupa, A.
    Bis-Wencel, H.
    Kiciński, P.
    Luchowska-Kocot, D.
    Krukowski, H.
    Nowicki, G.J.
    Panasiuk, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/28761891.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2021, 28, 4; 676-680
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Factors influencing serum chemerin and kallistatin concentrations in patients with alcohol-induced liver cirrhosis
    Autorzy:
    Prystupa, A.
    Kiciński, P.
    Luchowska-Kocot, D.
    Sak, J.
    Prystupa, T.K.
    Tan, Y.-H.
    Panasiuk, L.
    Załuska, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2082078.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    alcohol-induced liver cirrhosis
    chemerin
    kallistatin
    Opis:
    Introduction. In Poland, an increasing number of patients are hospitalized due to liver diseases. One of the common liver diseases is cirrhosis, which can be caused by alcohol, viral hepatitis, autoimmune processes and metabolic diseases. Materials and method. The study included 99 patients with alcoholic cirrhosis from the Lublin region of Eastern Poland. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The concentrations of serum kallistatin and chemerin were determined using ELISA kits. Objective. The aim of the study is to evaluate serum levels of kallistatin and chemerin in patients with different stages of alcoholic liver cirrhosis. Results. The highest chemerin level was found in the control group – 182.6±80.4 ng/ml. In other stages of liver cirrhosis, the following levels were observed: 175.7±62.7 ng/ml in Child-Pugh stage A (Ch-P A), 150.2±59.7 ng/ml in Ch-P B and 110.3±73.6 ng/ml in Ch-P C. Significant differences in chemerin levels between controls and Ch-P C patients (p=0.01), as well as between the Ch-P A patients and Ch-P C patients (p=0.02), were demonstrated. The highest kallistatin level was demonstrated in the control group – 8.2±3.5 μg/ml. In other stages of liver cirrhosis, the following concentrations were found: 7.2±27 μg/ml in Ch-P A, 4.4±2.2 μg/ml in Ch-P B and 3.5±1.9 μg/ml in Ch-P C (Tab. 3). Statistically significant differences were observed between controls and Ch-P B patients (p<0.001), controls and Ch-P C patients (p<0.001), Ch-P A and Ch-P B patients (p=0.01), as well as Ch-P A and Ch-P C patients (<0.001). Conclusions. The levels of chemerin and kallistatin decrease with progression of liver damage during alcoholic liver cirrhosis. The impairment of its synthetic function leads to reductions in levels of the adipokines studied.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 143-147
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of novel serum markers of fibrosis and angiogenesis in patients with alcoholic liver cirrhosis
    Autorzy:
    Prystupa, A.
    Kiciński, P.
    Luchowska-Kocot, D.
    Nowicki, G.
    Dzida, G.
    Myśliński, W.
    Zakrzewski, M.
    Mosiewicz, J.
    Panasiuk, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/28762972.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 4; 568-573
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Afamin and adropin in patients with alcohol-induced liver cirrhosis
    Autorzy:
    Prystupa, A.
    Kiciński, P.
    Luchowska-Kocot, D.
    Sak, J.
    Prystupa, T.
    Chen, K.-H.
    Chen, Y.-H.
    Panasiuk, L.
    Załuska, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081906.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    alcoholic liver cirrhosis
    Adropin
    Child-Pugh score
    afamin
    Opis:
    The aim of the study was to determine serum concentrations of afamin and adropin in patients with alcoholic liver cirrhosis and to define their correlation with the stage of disease. The study included 99 patients with alcoholic cirrhosis from the region of Lublin, (Eastern Poland). Liver cirrhosis was diagnosed based on clinical features, history of heavy alcohol consumption, laboratory tests and abdominal ultrasonography. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The serum afamin and adropin concentrations were determined using ELISA kits. The concentration of afamin was found to be significantly lower in patients with compensated alcoholic liver cirrhosis, i.e. P-Ch B (85.1±40.6 μg/ml) and P-Ch C (56.4±32.3 μg/ml) individuals, compared to the control group (135.9±43.6 μg/ml); p-value was <0.01 and <0.001, respectively. As far as adropin is concerned, a reverse relationship was demonstrated: the highest concentration was found in patients with P-Ch C (11.7±5.7 ng/ml) cirrhosis. Furthermore, the above concentration was significantly higher compared to patients with P-Ch A cirrhosis (7.2±2.8 ng/ml; p<0.05) and controls (7.5±2.6 ng/ml; p<0.05). The concentration of afamin decreases with the severity of alcoholic liver cirrhosis, which most likely results from impaired hepatic synthesis. Otherwise, the higher the stage of disease according to the Child-Pugh score, the higher the concentration of adropin.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 3; 527-531
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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