- Tytuł:
- Implementation of extended prolonged venous thromboembolism prophylaxis with rivaroxaban after major abdominal and pelvic surgery – overview of safety and early outcomes
- Autorzy:
-
Tyselskyi, Volodymyr
Wong, Daniel
Tryliskyy, Yegor
Poylin, Vitaliy
Kebkalo, Andrey - Powiązania:
- https://bibliotekanauki.pl/articles/1391804.pdf
- Data publikacji:
- 2020
- Wydawca:
- Index Copernicus International
- Tematy:
-
colorectal surgery
Rivaroxaban
venous thromboembolic events
VTE - Opis:
- Purpose: Venous thromboembolism (VTE) after colorectal surgery is a well-documented complication, resulting in a general recommendation of extended post-discharge prophylaxis. Rivaroxaban, a factor Xa inhibitor, is a daily tablet approved for treatment of VTE and prophylaxis after orthopedic surgery. Aim: The purpose of this study is to evaluate the safety of rivaroxaban for extended prophylaxis after major abdominal and pelvic surgery. Methods: This is a retrospective review of patients undergoing major colorectal surgery at a regional hospital in Kiev, Ukraine. Patients received peri-operative VTE prophylaxis with subcutaneous heparin and then transitioned to rivaroxaban for a total of 30 days. Occurrences of major or minor bleeding, blood transfusion, and a need for re-intervention were noted. Phone surveys were administered on post-operative day 30 to assess compliance and satisfaction with the regimen. Results: A total of 51 patients were included in the study with an average age of 62.4 years. Seventy-one percent of the cases were abdominal, 29% were pelvic cases and 59% were done laparoscopically. There was one episode of major intra-abdominal bleeding requiring return to the operating room. There were 2 minor bleeding episodes which did not require intervention. There were no VTE events in the group. The phone survey response rate was 100%. All but one patient reported having completed the full course of rivaroxaban. Patients reported that oral prophylaxis was easy to adhere to and preferable compared to injections. Conclusion: Implementation of extended prophylaxis with rivaroxaban is easy, safe and does not increase rates of postoperative bleeding.
- Źródło:
-
Polish Journal of Surgery; 2020, 92, 6; 22-27
0032-373X
2299-2847 - Pojawia się w:
- Polish Journal of Surgery
- Dostawca treści:
- Biblioteka Nauki
Artykuł