Autor: Nowakowska-Świrta, Ewa - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Occupational asthma caused by samba (Triplochiton scleroxylon) wood dust in a professional maker of wooden models of airplanes: A case study
Autorzy:: Krawczyk-Szulc, Patrycja
Wiszniewska, Marta
Pałczyński, Cezary
Nowakowska-Świrta, Ewa
Kozak, Anna
Walusiak-Skorupa, Jolanta
Powiązania:: https://bibliotekanauki.pl/articles/2178859.pdf
Data publikacji:: 2014-06-21
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: occupational asthma
wood dusts
samba
triplochiton scleroxylon
specific inhalation challenge test
Opis:: Objectives: Wood dust is a known occupational allergen that may induce, in exposed workers, respiratory diseases including asthma and allergic rhinitis. Samba (obeche, Triplochiton scleroxylon) is a tropical tree, which grows in West Africa, therefore, Polish workers are rarely exposed to it. This paper describes a case of occupational asthma caused by samba wood dust. Material and Methods: The patient with suspicion of occupational asthma due to wood dust was examined at the Department of Occupational Diseases and Clinical Toxicology in the Nofer Institute of Occupational Medicine. Clinical evaluation included: analysis of occupational history, skin prick tests (SPT) to common and occupational allergens, determination of serum specific IgE to occupational allergens, serial spirometry measurements, metacholine challenge test and specific inhalation challenge test with samba dust. Results: SPT and specific serum IgE assessment revealed sensitization to common and occupational allergens including samba. Spirometry measurements showed mild obstruction. Metacholine challenge test revealed a high level of bronchial hyperactivity. Specific inhalation challenge test was positive and cellular changes in nasal lavage and induced sputum confirmed allergic reaction to samba. Conclusions: IgE mediated allergy to samba wood dust was confirmed. This case report presents the first documented occupational asthma and rhinitis due to samba wood dust in wooden airplanes model maker in Poland.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2014, 27, 3; 512-519
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Immunological determinants in a murine model of toluene diisocyanate-induced asthma
Autorzy:: Świerczyńska-Machura, Dominika
Walusiak-Skorupa, Jolanta
Nowakowska-Świrta, Ewa
Piasecka-Zelga, Joanna
Świercz, Radosław
Pałczyński, Cezary
Powiązania:: https://bibliotekanauki.pl/articles/2180077.pdf
Data publikacji:: 2012-09-01
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: toluene diisocyanate
occupational asthma
murine model
allergic infl ammation
cytokines
Opis:: Objectives: Diisocyanates (DIC) are highly reactive, low-molecular-weight chemicals which are the leading cause of occupational asthma (OA). The aim of the study was to analyze certain aspects of the pathogenesis of allergic infl ammation in the airways induced by toluene diisocyanate (TDI) in an experimental model in mice. Materials and Methods: The experiment was carried out on 50 female BALB/cJ/Han/IMP mice, which were exposed by inhalation (intranasal and in the inhalation chamber) to toluene diisocyanate (2,4-TDI). After the experiment, the bronchoalveolar lavage fluid (BALF) was collected from the animals, and the composition of the induced infl ammatory cells, and the concentrations of certain cytokines (IL-4, IL-5, TNF-α) were evaluated. Results: The total number of cells in BALF of the examined group of mice was signifi cantly higher compared to the control mice. There was also a signifi cant increase in neutrophils and eosinophils in the study group compared to the controls. The number of lymphocytes and macrophages did not differ signifi cantly between the two groups. A statistically signifi cant increase in the level of TNF-α was shown to occur in the group exposed to toluene diisocyanate in comparison to the control group. The concentration of IL-4 increased in the study group, compared to the control one, but the differences did not reach the level of signifi cance, p > 0.05. Such difference was not observed for IL-5. Conclusions: We developed a murine model of TDI-induced asthma which caused the infl ux of infl ammatory cells like eosinophils and neutrophils in the bronchoalveolar lavage fl uid (BALF) in the TDI-treated mice. The increase of the concentration of some proinfl ammatory cytokines (TNF-α, IL-4) in BALF from the exposed mice was also observed.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2012, 25, 4; 492-498
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Occupational allergy to birds within the population of Polish bird keepers employed in zoo gardens
Autorzy:: Świderska-Kiełbik, Sylwia
Krakowiak, Anna
Wiszniewska, Marta
Nowakowska-Świrta, Ewa
Walusiak-Skorupa, Jolanta
Śliwkiewicz, Konrad
Pałczyński, Cezary
Powiązania:: https://bibliotekanauki.pl/articles/2185387.pdf
Data publikacji:: 2011-09-01
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: allergens
birds
allergy
occupational exposure
Opis:: Objectives: To evaluate the risk factors for the development of occupational allergy to birds among Polish zoo garden keepers. Methods: A total of 200 bird zookeepers employed in the Polish zoo gardens in Łódź, Warsaw, Gdańsk, Chorzów and Płock and exposed occupationally to bird allergens were examined using a questionnaire, skin prick tests (SPTs) to common allergens and bird allergens, spirometry and cytograms of nasal swab. The level of total IgE in serum and serum-specific IgE to parrot, canary, pigeon feathers and serum were also evaluated. Results: Eight percent of bird zookeepers were sensitized to at least one of the bird allergens. The most frequent allergens yielding positive SPT results were D. farinae — 32 cases (16%), D. pteronyssinus — 30 cases (15%) and grass pollens (16.5%). In the studied group, allergen-specific IgE against bird allergens occurred with the following frequency: 87 (43.5%) against canary feathers and/or serum, 80 (40%) against parrot feathers and/or serum and 82 (41%) against pigeon feathers and/or serum. Occupational allergy was diagnosed in 39 (26.5%) cases, occupational rhinitis was present in 22 (15%) cases, occupational asthma in 20 (13.6%) subjects, occupational conjunctivitis in 18 (12.2%) cases, whereas occupational skin diseases in 11 (7.5%) cases. More eosinophils were found in nose swab cytograms among bird zookeepers with occupational airway allergy. Conclusions: The findings indicate that occupational allergy to birds is an important health problem among zoo bird keepers in Poland.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2011, 24, 3; 292-303
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Work-related respiratory symptoms among health centres cleaners: A cross-sectional study
Autorzy:: Lipińska-Ojrzanowska, Agnieszka
Wiszniewska, Marta
Świerczyńska-Machura, Dominika
Wittczak, Tomasz
Nowakowska-Świrta, Ewa
Pałczyński, Cezary
Walusiak-Skorupa, Jolanta
Powiązania:: https://bibliotekanauki.pl/articles/2178854.pdf
Data publikacji:: 2014-06-21
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: cleaners
occupational allergy
work-related respiratory symptoms
work-related asthma
WRA
Opis:: Objectives: Several studies, mostly based on questionnaire-derived data, have shown an increased risk of allergic diseases, especially asthma, among cleaners. The risk factors and etiological mechanisms are still being investigated. Occupational exposure to various chemical and biological agents may induce specific sensitization and/or irritant effects. The aim of our study was to estimate the prevalence of work-related symptoms suggesting the presence of allergic disease reported by cleaners, and to relate them to the results of commercially available and standardized objective tests used for screening detection of occupational sensitization and chronic respiratory disorders. Material and Methods: A cross-sectional study was performed among 142 Polish workers of cleaning service in their workplaces. A detailed questionnaire, skin prick tests to common allergens and chemicals used by these workers for cleaning purposes (chloramine T, chlorhexidine, formaldehyde, glutaraldehyde, benzalconium chloride), total and specific serum IgE antibodies to disinfectants and rest spirometry were performed in all the subjects. Results: Fifty nine percent of all the subjects declared occurrence of at least 1 symptom suggesting allergic ailment during cleaning activities at work. Skin prick tests and specific serum IgE antibodies to disinfectants were negative in all the subjects. In 8 cases wheezing was detected during auscultation, but only in 5 of them obstructive pattern in rest spirometry was found. Conclusions: Occupational allergic causation of symptoms among cleaners could be less likely than work-related symptoms associated with exacerbations of new-onset or pre-existing respiratory diseases. Therefore, in this group of workers, mainly the non-specific irritant impact of chemicals on airways should be taken into consideration.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2014, 27, 3; 460-466
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Occupational exposure to diisocyanates in polyurethane foam factory workers
Autorzy:: Świerczyńska-Machura, Dominika
Brzeźnicki, Sławomir
Nowakowska-Świrta, Ewa
Walusiak-Skorupa, Jolanta
Wittczak, Tomasz
Dudek, Wojciech
Bonczarowska, Marzena
Wesolowski, Wiktor
Czerczak, Sławomir
Pałczyński, Cezary
Powiązania:: https://bibliotekanauki.pl/articles/2177097.pdf
Data publikacji:: 2015-08-10
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: biomarkers
diisocyanates
asthma
polyurethanes
biological monitoring
occupational exposure
occupational diseases
Opis:: Objectives The aim of the study was to evaluate health effects of occupational exposure to diisocyanates (DIC) among polyurethane foam products factory workers. Material and Methods Thirty workers had a physical examination, skin prick tests with common allergens, allergen-specific immunoglobulin E (IgE) antibodies to diisocyanates and pulmonary function tests. Concentrations of selected isocyanates in the workplace air samples as well as concentration of their metabolites in the urine samples collected from the workers of the plant were determined. Results The most frequent work-related symptoms reported by the examined subjects were rhinitis and skin symptoms. Sensitization to at least 1 common allergen was noted in 26.7% of the subjects. Spirometry changes of bronchial obstruction of a mild degree was observed in 5 workers. The specific IgE antibodies to toluene diisocyanate (TDI) and 4,4’-methylenebis(phenyl isocyanate) (MDI) were not detected in any of the patients’ serum. Cellular profiles of the collected induced sputum (ISP) did not reveal any abnormalities. Air concentrations of TDI isomers ranged 0.2–58.9 μg/m³ and in 7 cases they exceeded the Combined Exposure Index (CEI) value for those compounds. Concentrations of TDI metabolites in post-shift urine samples were significantly higher than in the case of pre-shift urine samples and in 6 cases they exceeded the British Biological Monitoring Guidance Value (BMGV – 1 μmol amine/mol creatinine). We didn’t find a correlation between urinary concentrations of TDI, concentrations in the air and concentrations of toluenediamine (TDA) in the post shift urine samples. Lack of such a correlation may be an effect of the respiratory protective equipment use. Conclusions Determination of specific IgE in serum is not sensitive enough to serve as a biomarker. Estimation of concentrations of diisocyanate metabolites in urine samples and the presence of work-related allergic symptoms seem to be an adequate method for occupational exposure monitoring of DIC, which may help to determine workers at risk as well as to recognize hazardous workplaces.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2015, 28, 6; 985-998
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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