- Tytuł:
- Assessment of cytotoxic and antimicrobial activity of selected gingival haemostatic agents – in vitro study
- Autorzy:
-
Szymonowicz, Maria
Rusak, Agnieszka
Pajączkowska, Magdalena
Nowicka, Joanna
Wiśniewska, Kamila
Żywicka, Bogusława
Rybak, Zbigniew
Dobrzyński, Maciej - Powiązania:
- https://bibliotekanauki.pl/articles/27324123.pdf
- Data publikacji:
- 2020
- Wydawca:
- Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
- Tematy:
-
haemostatic agents
cytotoxicity
gingiva retraction
antimicrobial activity
środki hemostatyczne
cytotoksyczność
retrakcja dziąsła
Aktywność przeciwbakteryjna - Opis:
- Purpose: The present research aimed to determine whether and how the aluminium chloride – based materials affect the cell line of the bacterial line and fungi. Methods: Cytotoxicity of haemostatic astringents: Alustat (liquid), Alustat (gel), Alustat (foam), Alustin, Hemostat, Racestyptine and Traxodent containing AlCl3 was conducted on L929 cell line with the use of MTT and SRB assays. The antimicrobial activity (CFU and MIC) against C. albicans, S. mutans, L. rhamnosus was determined. Results: In the MTT results, cell viability for all agents were very low. In SRB, the lowest cytotoxicity was demonstrated for Hemostat and Alustat (foam), Traxodent and Racestyptine. Total reduction of the CFU of S. mutans was observed. Alustat (gel) and Alustat (liquid) completely inhibited the growth of C. albicans, S. mutans and L. rhamnosus. Conclusions: The viability of L929 cells obtained in the SRB assay is more reliable than that obtained in the MTT assay, in the case of gingival haemostatic agents.
- Źródło:
-
Acta of Bioengineering and Biomechanics; 2020, 22, 3; 185--198
1509-409X
2450-6303 - Pojawia się w:
- Acta of Bioengineering and Biomechanics
- Dostawca treści:
- Biblioteka Nauki
Artykuł