Autor: Mirowski, Marek - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: The effect of hydrazine derivatives of 3-formylchromones on angiogenic basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanoma cell line WM-115
Autorzy:: Łazarenkow, Andrzej
Michalska, Marta
Mirowski, Marek
Słomiak, Krzysztof
Nawrot-Modranka, Jolanta
Powiązania:: https://bibliotekanauki.pl/articles/1038629.pdf
Data publikacji:: 2017
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: angiogenesis
basic fibroblast growth factor
fibroblast growth factor receptor 1
human melanoma
hydrazone derivatives of benzo-γ-pyrones
Opis:: The hydrazine derivatives of benzopyrones remain an unexplored group of chemical compounds. This preliminary study investigates the influence of A-5, CH-3 and K-2 derivatives at concentrations of 1, 10, 100 nM and 1 μM on selected biochemical factors of a melanoma cell line WM-115, with regard to their potential angiogenic properties. The studied compounds were found to influence cell proliferation, as well as total protein, bFGF and FGFR1 concentration.
Źródło:: Acta Biochimica Polonica; 2017, 64, 3; 585-590
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 2.

Tytuł:: The influence of chromone based hydrazones on lipid peroxidation and bFGF concentration in the HL-60 cell line
Autorzy:: Łazarenkow, Andrzej
Michalska, Marta
Gorąca, Anna
Mirowski, Marek
Nawrot-Modranka, Jolanta
Piechota-Polanczyk, Aleksandra
Powiązania:: https://bibliotekanauki.pl/articles/1039590.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: hydrazone
chromone
phosphorohydrazone
HL-60
lipid peroxidation
bFGF
Opis:: Natural and synthetic derivatives of benzo-γ-pyrones (i.e. flavones, chromones, and coumarins) and their synthetic analogues possess a wide range of biological properties in vitro and in vivo. In this paper we investigated the influence of two hydrazone compounds of chromones, 3-{[(2-dimethoxytiophosphoryl)-2-methylhydrazono]-methyl}-chromen-4-one (CH-3) and 2-amino-6-chloro-3-[(2-hydroxyethyl)-hydrazonomethyl]-chromen-4-one (A-12), on lipid peroxidation and bFGF concentration in the HL-60 cells. Both of the studied compounds had a significant influence on bFGF and TBARS in ranges -137.20 ~ 380.26% and -81.66 ~ -28.68%, respectively, in comparison with the control (counted as 0 %).
Źródło:: Acta Biochimica Polonica; 2013, 60, 2; 259-262
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Informacja