- Tytuł:
- Differences in the expression of selected genes associated with cell stress response in a PTSD patient and in healthy individuals – a case study
- Autorzy:
-
Rasmus, Anna
Półrola, Paweł
Góral-Półrola, Jolanta
Żychowska, Małgorzata
Mirski, Andrzej
Knapik, Henryk - Powiązania:
- https://bibliotekanauki.pl/articles/986669.pdf
- Data publikacji:
- 2017
- Wydawca:
- Instytut Medycyny Wsi
- Tematy:
-
cell stress
ptsd patient
expression of selected genes
healthy individuals - Opis:
- Objective. The aim of the study was determination of the level in expression genes associated with cell stress response in a patient with PTSD. Case study. A 57-year-old PTSD patient, A.P., was the subject of the study. Blood samples were taken from the ulnar vein to assess the relative expression of the tested genes in leukocytes via a quantitative reverse transcription polymerase chain reaction (qRT-PCR). Results. A considerably decreased level in the expression HSF-1, NF-kB, Hif-1 and IL6 m-RNA was observed in the patient when compared to the control group. A low expression in HSPA1A, HSPB1, IL10 and CRP m-RNA compared with the control group was also noted. Conclusion. It is possible that the lower level of transcriptional factors: HSF-1, NF-kB and Hif-1 as well as IL6 m-RNA may be associated with the effect of the PTSD patient’s treatment.
- Źródło:
-
Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966 - Pojawia się w:
- Annals of Agricultural and Environmental Medicine
- Dostawca treści:
- Biblioteka Nauki
Artykuł