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    Wyświetlanie 1-4 z 4
    Tytuł:
    Antifungal drugs resistance profiles of C. albicans strains isolated from the oral cavity of children and adolescents
    Autorzy:
    Kamińska, Agnieszka
    Malm, Anna
    Szymańska, Jolanta
    Powiązania:
    https://bibliotekanauki.pl/articles/895246.pdf
    Data publikacji:
    2019-10-30
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    drug resistance
    oral cavity
    children and adolescents
    C. albicans
    Opis:
    Fungi, mainly yeast-like fungi of the Candida genus, and especially the species Candida albicans, occupy an important place among microorganisms that colonize the oral cavity. The aim of the paper was to assess the susceptibility of different strains to some antifungal drugs. The study material consisted of swab samples taken from the buccal mucosa of 376 healthy individuals of both genders, from neonate to18 years. C. albicans strains were isolated in 79 persons. To evaluate drug resistance phenotypes of the isolated C. albicans strains FungitestTM (Bio-Rad) was used. The study showed that in different age groups the percentage of the tested C. albicans isolates susceptible to all the tested azole drugs varied from 76% to 95%. Drug resistant strains were found only in the eldest age group (4.8%). Phenotypic diversity (drug resistance types) of the studied isolates indicates a wide range of adaptation possibilities enabling colonization of various ecological niches in the oral cavity ecosystem. The presence of C. albicans strains intermediate or resistant to azole drugs among the tested isolates may be due to overuse of that drug group in general therapy and in the oral cavity treatment.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 5; 873-876
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Assessment of Candida spp. frequency in the oral cavity ontocenosis of healthy individuals in different age groups
    Autorzy:
    Szymańska, Jolanta
    Wójtowicz, Agnieszka
    Malm, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/972336.pdf
    Data publikacji:
    2016
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    fungi
    Candida spp
    Candida albicans
    Opis:
    Introduction. Among the microorganisms colonizing the oral cavity ontocenosis, an important role is played by fungi: mainly yeast-like fungi of the Candida genus, and especially by the species C. albicans. Objective. The aim of this study was to evaluate the frequency of oral colonization by Candida species in healthy individuals of different age groups, and to identify the species of the isolates. Materials and method. The fungi were isolated from the oral cavities of 654 healthy individuals of both genders, representing different age groups, and the species of the isolates were determined. Initial identification of the yeast-like fungi was made based on the macroscopic appearance of the colonies on Sabouraud’s medium, and the growth of coloured colonies on ChromAgar Candida medium. API 20 C AUX microtest (bioMerieux) was used to identify the most frequently found species of Candida spp. Results. The frequency of Candida isolation from the oral cavity ontocenosis in healthy individuals of different age groups was assessed as 30.6%. The oral cavity ontocenosis was colonized mainly by the yeast-like fungi of C. albicans species: they were found in 24.5% of the tested population, while the frequency of oral cavity colonization by non-albicans Candida spp. was 6.1%. Seven species of non-albicans Candida spp. were identified: C. glabrata, C. inconspicua, C. famata, C. tropicalis, C. parapsilosis, C. lusitaniae, and C. kefyr. Conclusions. In the Polish population, 30.6% of the oral cavity ontocenosis is colonized by Candida yeast-like fungi, while C. albicans is the fungus that colonizes oral cavity ontocenosis most frequently. The frequency of oral cavity ontocenosis colonization with Candida spp (including C. albicans) increases with age.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2016, 10, 2; 91-94
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Socjodemograficzne uwarunkowania sposobów radzenia sobie w sytuacjach trudnych przez personel pielęgniarski
    Autorzy:
    Kirenko, Janusz
    Sienkiewicz, Ewa
    Szymańska, Jolanta
    Malm, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/606967.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
    Tematy:
    nursing staff, problematic situations, stress, coping
    personel pielęgniarski, sytuacje problemowe, stres, radzenie sobie
    Opis:
    The results of coping with problematic situations can be assessed by analyzing physiological responses, motor activities and emotional symptoms. The more effectively a person copes in a problematic situation, the better his/her psychosocial functioning. The adequacy of the selected coping profile affects the state of somatic and mental health. The most important feature of coping should be flexibility – adaptation to changing conditions. The aim of the study was to assess the sociodemographic factors conditioning coping with difficult situations by nursing staff. The study included an 81-member group of nurses. The original “certificate of origin” was used for the sociodemographic characteristics of the subjects studied and the Questionnaire for coping with problems (WCQ Lazarus and Folkman) was provided. The study showed that there is a relationship between dealing with difficult situations by nursing staff and the place of residence, age and professional experience. Individual strategies of coping with difficult situations by respondents do not correlate with gender and education. The respondents most often choose the coping profile described as a positive attitude. Concentration on the problem and a positive attitude have the greatest impact on the psychosocial functioning of the respondents. The skills of coping with problems in difficult situations by nursing staff are partially conditioned by sociodemographic analysis. Interpersonal skills in the field of social communication and immune resources are of great importance. It is necessary to extend the research with the determinants of personality dispositions of nursing staff in order to determine their intra-personal resources, psychosocial – sense of coherence, self-esteem and social support. Obtained information on occupational predispositions may be useful in vocational education and training of nursing staff.
    Rezultaty radzenia sobie w sytuacjach problemowych można ocenić, analizując reakcje fizjologiczne, czynności motoryczne i objawy emocjonalne. Im efektywniej człowiek radzi sobie w sytuacji problemowej, tym lepsze jest jego funkcjonowanie psychospołeczne. Adekwatność wybranego profilu radzenia sobie wpływa na stan zdrowia somatycznego i psychicznego. Najistotniejszą cechą radzenia sobie powinna być elastyczność – dopasowanie do zmieniających się warunków. Celem badań była ocena socjodemograficznych czynników warunkujących radzenie sobie w sytuacjach trudnych przez personel pielęgniarski. Badaniami objęto 81‒osobową grupę pielęgniarek i pielęgniarzy. Wykorzystano autorską metryczkę dotyczącą socjodemograficznej charakterystyki badanych osób oraz Kwestionariusz radzenia sobie z problemami (WCQ Lazarus i Folkman). Na podstawie wyników badań stwierdzono, że istnieje zależność pomiędzy radzeniem sobie w sytuacjach trudnych przez personel pielęgniarski a miejscem zamieszkania, wiekiem i stażem pracy w zawodzie. Poszczególne strategie radzenia sobie w sytuacjach trudnych badanych osób nie korelują z płcią i wykształceniem.
    Źródło:
    Lubelski Rocznik Pedagogiczny; 2018, 37, 3
    0137-6136
    Pojawia się w:
    Lubelski Rocznik Pedagogiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    In vitro susceptibility of oral Candida albicans isolates to chlorhexidine
    Autorzy:
    Biernasiuk, Anna
    Szymańska, Jolanta
    Kustra, Agata
    Korona-Głowniak, Izabela
    Malm, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/895468.pdf
    Data publikacji:
    2018-06-30
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    antifungal agents
    Candida albicans
    chlorhexidine
    Opis:
    Fungal infections are an important medical problem in patients from different risk groups. The majority of these infections are caused by Candida spp., with over 50 % due to C. albicans. The purpose of the study was to evaluate in vitro chlorhexidine effect on C. albicans colonizing the mouth and throat isolated from 5 population groups. The study material included the reference strains of C. albicans ATCC 2091 and C. albicans ATCC 10231, routinely used for evaluation of antimicrobials, and 120 clinical isolates of C. albicans from: hospitalized cancer patients (30 isolates), chronic HCV patients (31 isolates), immunocompromised patients (28 isolates), healthy school-age children (31 isolates), elderly people – aged 65 years or older (30 isolates). Chlorhexidine inhibited the growth of C. albicans at the concentrations of 0.625-5 µg/ml (in particular, 2.5 µg/ml solution was effective against strains from immunocompromised patients and 5 µg/ml – against the remaining isolates). The yeasts were also killed by 2.5-20 µg/ml chlorhexidine solutions. The concentration of 5 µg/ml was particularly active against the strains isolated from the elderly, immunocompromised and lung cancer patients, while 10 µg/ml inhibited the growth of the strains from the remaining two groups. Moreover, C. albicans isolates from hepatitis C patients and healthy children comparing to strains from the elderly were less sensitive to chlorhexidine fungicidal effect and these differences were statistically significant. According to our studies, the fungicidal effect of chlorhexidine seems to depend on the origin of the tested oral C. albicans strains from various patient groups.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 3
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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