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Wyszukujesz frazę "Lackner, J. M." wg kryterium: Wszystkie pola


Wyświetlanie 1-9 z 9
Tytuł:
The influence of the surface topography on the cell-differentiation effect
Autorzy:
Lackner, J. M.
Major, R.
Powiązania:
https://bibliotekanauki.pl/articles/284478.pdf
Data publikacji:
2018
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
plasticity
cells
therapy
Źródło:
Engineering of Biomaterials; 2018, 21, 148; 22
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Material engineering in cardiovascular reconstruction
Autorzy:
Major, R.
Lackner, J. M.
Gonsior, M.
Plutecka, H.
Powiązania:
https://bibliotekanauki.pl/articles/284617.pdf
Data publikacji:
2018
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
cardiovascular reconstruction
composites
polymers
Opis:
Reconstruction of the cardiovascular system: The aim of the work is to minimize thrombus formation life threatening in the pulsatile heart assist chamber, by the use of a new biomimetic heart valve made on the basis metal-polymer composites. The heart prostheses are dedicated to support the heart of patients with late heart disease failure. They are dedicated to therapy related to self-regeneration or as a bridge for transplantation. In the future, they will be able to help treatment with gene therapy for myocardial infarction. Systems with valves mechanically generate plaque activation by shear stress. This is due to the narrow gap that is between the petal and the ring. Composite materials and a new valve design can minimize this problem. Injected polyurethane with a metallic, titanium bonded insert optimal microscale flexibility with macro-stiffness for ensuring appropriate mechanical functions of the valve.
Źródło:
Engineering of Biomaterials; 2018, 21, 148; 19
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vitro hemocompatibility of thin films materials for direct blood contact
Autorzy:
Trembecka-Wójciga, K.
Major, R.
Lackner, J. M.
Plutecka, H.
Powiązania:
https://bibliotekanauki.pl/articles/285250.pdf
Data publikacji:
2015
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
hemocompatibility
thin film
protein adsorption
shear stresses
Opis:
When designing new biomaterials for tissue contact devices it is important to consider their architecture as it affects different cell response. Surface modification of tubular structures requires the use of different techniques than in the case of flat samples. Similarly, analytical techniques also need to be adapted to the specific shape of substrate. For blood contacting devices this issue is critical because of shear forces generated by fluid flow and responsible for blood components activation. This necessitates the use of diagnostic techniques dedicated for material analysis in dynamic conditions in order to simulate physiological conditions. In the frame of the work, the flat samples as well as tube like elements were considered. The flat samples were prepared for basic research. Based on the results of the basic research the thin coatings were selected for the internal side of the tube like elements which have been analysed in contact with blood using blood flow simulator. The cross section of the coating-substrate interaction was tested using transmission electron microscopy. The attachment of cells to coatings was determined by radial flow chamber. Hemocompatible analysis was carried out in two ways. The quality of the blood after the dynamic test was analysed using flow cytometry. In this case the aggregates formation, platelet consumption and apoptosis derived microparticles were considered. The amount of cells adhered to the materials surfaces was determined by confocal laser microscopy.
Źródło:
Engineering of Biomaterials; 2015, 18, 132; 2-8
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Development of surface modification methods for ReligaHeart® cardiac support system
Autorzy:
Major, R.
Kustosz, R.
Trembecka-Wójciga, K.
Lackner, J. M.
Major, B.
Powiązania:
https://bibliotekanauki.pl/articles/352605.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
ReligaHeart® cardiac support system
pneumatic heart
blood-polymer barrier
proangiogenic effect
Opis:
The work is a review of the methods of the surface modification performed by the authors dedicated for for cardiac support system. It presents the evolution of designing the surface dedicated to direct contact with blood. Initially thin and ultrathin coatings were developed. They were designed as a blood-polymer barrier. The pneumatic heart assist devices are made of a medical grade polyurethane. A major milestone was to create advanced ceramic thin films expressing the flexible effects deposited by physical techniques. Coatings have evolved. Another milestone was the surface reproducing the microenvironment to capture progenitor cells from the bloodstream. Thin coatings were prepared, using methods of ion been, controlled residual stresses were introduced. Wrinkles appeared without cracking. This enabled taking control over the process of cell differentiation. Alternatively, the tissue inspired structure resulted of the coating in the form of extracellular matrix. The outer surface was modified with synthetic materials. This enabled the effective proteins docking to induce cell growth, recreating the luminal side of the blood vessel. Coagulation processes have been slowed down. In addition, it was found pro-angiogenic effect.
Źródło:
Archives of Metallurgy and Materials; 2016, 61, 3; 1399-1404
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biomechanical properties of the thin PVD coatings defined by red blood cells
Autorzy:
Trembecka-Wojciga, K.
Major, R.
Lackner, J. M.
Bruckert, F.
Jasek, E.
Major, B.
Powiązania:
https://bibliotekanauki.pl/articles/201364.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
biomechanical properties
thin PVD coatings
red blood cells
właściwości biomechaniczne
cienkie powłoki PVD
krwinki czerwone
Opis:
The measurement of the strength of bonds between biomaterials and cells is a major challenge in biotribology since it allows for the identification of different species in adhesion phenomena. Biomaterials, such as diamond-like carbon (DLC), titanium, and titanium nitride, seem to be good candidates for future blood-contact applications. These materials were deposited as thin films by the hybrid pulsed laser deposition (PLD) technique to examine the influence of such surfaces on cell behavior. The biomaterial examinations were performed in static conditions with red blood cells and then subjected to a dynamical test to observe the cell detachment kinetics. The tests revealed differences in behavior with respect to the applied coating material. The strongest cell-biomaterial interaction was observed for the carbon-based materials compared to the titanium and titanium nitride. Among many tests, a radial flow interaction analysis gives the opportunity to analyze cell adhesion to the applied material with the high accuracy. Analysis of concentrates helped to select materials for further dynamic tests on blood using an aortic flow simulator. In this case, the platelet adhesion to the surface and their degree of activation was analyzed. The quality of the selected coating was tested using a scratch test. The analyses of the microstructure were done using high resolution transmission electron microscopy. The phase composition and the residual stress were analyzed using X-ray diffraction methods.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2015, 63, 3; 697-705
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Migration channels produced by laser ablation for substrate endothelialization
Autorzy:
Major, R.
Maksymow, K.
Marczak, J.
Lackner, J.
Kot, M.
Major, B.
Powiązania:
https://bibliotekanauki.pl/articles/201285.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
inorganic coatings
pulsed laser ablation
tissue scaffold
endothelial cells migration
Opis:
Seeding of cells on functional, biocompatible scaffolds is a crucial step in achievement the desired engineered tissue. In the present study, a pulsed laser modification onto inorganic substrate was made to promote endothelium cells migration and spread. Presented scaffolds were fabricated on carbon and titanium based coatings. Fabricated films provided very good mechanical properties together with a chemical stability preservation. The substrate modification consisted of grid-like template fabrication of micrometer size meshes. The microstructure analysis of laser traces revealed the grain size increase in the zone of laser beam interaction, which exerts an influence on a surface topography. Endothelium cells locomotion was observed within 10 day time period. As a result it was shown that the modified area enhanced cells adhesion with a preferred static behavior. The performed research work improved our understanding on the pulsed laser ablation process and template size influence on cells spatial arrangement. It constituted an important step towards fabrication of inorganic, biocompatible scaffolds for successful substrate endothelialization.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2012, 60, 2; 337-342
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Initial in vivo biocompatybility evaluation of biomaterials used in the new biomimetic heart valve
Autorzy:
Gonsior, M.
Zawidlak-Węgrzyńska, B.
Janiczak, K.
Gonsior, D.
Kustosz, R.
Major, R.
Lackner, J.
Powiązania:
https://bibliotekanauki.pl/articles/283829.pdf
Data publikacji:
2018
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
biomaterials
polyurethane
biocompatibility
Źródło:
Engineering of Biomaterials; 2018, 21, 148; 81
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Coatings with advanced microstructure for biomedical applications
Powłoki o złożonej architekturze do zastosowań biomedycznych
Autorzy:
Kot, M.
Major, Ł.
Major, R.
Lackner, J.
Pontié, M.
Powiązania:
https://bibliotekanauki.pl/articles/189614.pdf
Data publikacji:
2017
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
carbon coatings
multilayers
biotribology
nanohardness
friction
wear
powłoki węglowe
powłoki wielowarstwowe
biotribologia
nanotwardość
tarcie
zużycie
Opis:
The paper presents the effect of the complex architecture of Cr/CrN+a-C:H coatings on their mechanical and tribological properties. These advanced coatings were compared with CrN single coatings and Cr/CrN multilayers. All of them were deposited by the magnetron sputtering technique. The conducted tests allowed nanohardness, elasticity modulus, fracture toughness, and adhesion of coatings to steel substrates to be determined. Tribological tests were carried out under dry friction and in the presence of phosphate-buffered saline PBS and foetal bovine serum FBS. For all test conditions, the friction coefficient and the wear index of the produced coatings were determined. The lowest wear and the lowest coefficient of friction are exhibited by coatings with complex Cr/CrN+a-C:H architecture. Furthermore, they are also resistant to the highly corrosive PBS environment.
W pracy analizowano wpływ złożonej architektury powłok Cr/CrN+a-C:H na ich właściwości mechaniczne i tribologiczne. Porównywano je z powłokami pojedynczymi CrN i wielowarstwowymi Cr/CrN, które wytwarzano techniką magnetronowego rozpylania. Przeprowadzone badania umożliwiły określenie twardości, modułu sprężystości, odporności na pękanie i adhezji do podłoża. Testy tribologiczne przeprowadzono w warunkach tarcia suchego oraz w obecności roztworu soli fizjologicznej PBS i surowicy cielęcej FBS. Dla wszystkich warunków tarcia określono współczynnik tarcia oraz odporność na zużycie wytworzonych powłok. Najmniejszym zużyciem oraz najmniejszymi wartościami współczynnika tarcia charakteryzowały się złożone powłoki Cr/CrN+a-C:H. Przy tym są one także odporne na oddziaływanie korozyjne roztworu PBS.
Źródło:
Tribologia; 2017, 272, 2; 77-84
0208-7774
Pojawia się w:
Tribologia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Adaptive coatings a-C/MoS2
Powłoki adaptacyjne a-C/MoS2
Autorzy:
Kot, M.
Lackner, J.
Major, Ł.
Major, R.
Skalski, K.
Wiązania, G.
Zimowski, S.
Powiązania:
https://bibliotekanauki.pl/articles/189964.pdf
Data publikacji:
2018
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
adaptive coatings
chameleon coatings
nanohardness
friction
wear
powłoki adaptacyjne
powłoki kameleonowe
nanotwardość
tarcie
zużycie
Opis:
One of the latest ideas in surface engineering is the deposition of new kinds of coatings, called adaptive or chameleon. Based on literature review, the different mechanisms of the adaption of such coatings depend on the applied ranges of temperature and loads were compared. Moreover, the main directions of development of adaptive coatings were also presented. The paper includes results of single coatings, a-C and MoS2, as well composite coatings, a-C/MoS2, in which the mechanism of adaptation was expected. Indentation tests were carried out to determine nanohardness and elasticity modulus. The adhesion of coatings to steel substrates was studied by scratch testing, and tribological properties were studied using a high-temperature ball-on disc tribometer and tests results conducted at room temperature and at elevated temperatures up to 300°C. Results showed that composite coating, a-C/MoS2, can work over the entire range of temperatures with a low coefficient of friction 0.02–0.1 and wear index of 0.07–0.47•10–6 mm3/Nm. Whereas, a-C and MoS2 coatings exhibited a low coefficient of friction and a high wear resistance at low and high temperatures, respectively.
W pracy przedstawiono nowy kierunek w inżynierii powierzchni tworzenia powłok adaptacyjnych, zwanych także kameleonowymi. Na podstawie analizy literatury zestawiono różne mechanizmy adaptacji powłok, w zależności od zakresu stosowanych temperatur pracy i kierunki rozwoju takich powłok. Przedstawiono także wyniki badań własnych dla powłok pojedynczych a-C i MoS2 i na ich tle wyniki dla powłok a-C/MoS2, w których spodziewano się mechanizmu adaptacji. Przeprowadzono testy indentacyjne, z których wyznaczono ich nanotwardość i moduł sprężystości. Analizowano także adhezję powłok do podłoży stalowych przy użyciu testu zarysowania. Testy tribologiczne przeprowadzono w temperaturze pokojowej oraz w podwyższonej do 300°C. Uzyskane wyniki wykazały, że w odróżnieniu do powłok a-C i MoS2 powłoki a-C/MoS2 mogą pracować w całym zakresie badanych temperatur. Wskazują na to niskie wartości współczynnika tarcia 0,02–0,1 i wskaźnika zużycia 0,07–0,47•10–6 mm3/Nm.
Źródło:
Tribologia; 2018, 278, 2; 51-56
0208-7774
Pojawia się w:
Tribologia
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-9 z 9

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