Autor: Landowski, Piotr - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Diagnosis and treatment difficulties in 18-year-old male patient with hereditary hemochromatosis, chronic hepatitis B, Gilbert syndrome and ulcerative colitis
Autorzy:: Sikorska, Katarzyna
Liberek, Anna
Romanowski, Tomasz
Szlagatys-Sidorkiewicz, Agnieszka
Landowski, Piotr
Bielawski, Krzysztof
Powiązania:: https://bibliotekanauki.pl/articles/1039929.pdf
Data publikacji:: 2011
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: hereditary hemochromatosis
ulcerative colitis
chronic hepatitis B
Glibert syndrome
Opis:: Among possible causes of chronic hepatitis in adolescents most common are infections, autoimmune disorders and metabolic diseases. Thus, diagnostic procedures should be multidirectional. This study reports diagnosis and treatment difficulties in an 18-year-old male patient with hereditary hemochromatosis (HH), ulcerative colitis (UC), chronic hepatitis B (CHB) and Gilbert syndrome. The presented case illustrates problems in diagnostics related to the presence of numerous disease conditions in one patient. It should be taken into consideration that these diseases coexisting in one patient can mutually affect their symptoms creating specific diagnostic difficulties.
Źródło:: Acta Biochimica Polonica; 2011, 58, 2; 251-254
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Evaluation of clinical usefulness of serum neopterin determination in children with bacterial infections
Autorzy:: Plata-Nazar, Katarzyna
Luczak, Grażyna
Liberek, Anna
Dudzinska-Gehrmann, Julita
Sznurkowska, Katarzyna
Landowski, Piotr
Kaminska, Barbara
Powiązania:: https://bibliotekanauki.pl/articles/1039150.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: neopterin
children
urinary tract infections
Opis:: Neopterin (NPT) (6-D-erythro-trihydroxypropyl pteridin) is one of the indicators of the immune system activity. Elevated neopterin concentration occurs in diseases mostly involving stimulation of cellular immunity. The determination of neopterin concentration, usually in blood serum and urine but also in many other bodily fluids, has already been applied in many areas of medicine, such as transfusiology, transplantology, oncology, infectious diseases and autoimmunological diseases. Objective. The aim of this work is to evaluate clinical usefulness of serum neopterin determination in children with urinary tract infections of confirmed bacterial etiology. Material. The study involved 56 children with bacterial urinary tract infections - patients of the Clinic of Paediatrics, Paediatric Gastroenterology, Hepatology & Paediatric Nutrition of Medical University of Gdańsk in the years 2012-2013. The control group included 105 healthy children. Results. The values of NPT concentration in blood serum obtained in the group of children with urinary tract infections did not significantly differ from the values obtained in the control group. Conclusions. The determination of neopterin concentration in children with bacterial urinary tract infections is not a clinically useful parameter.
Źródło:: Acta Biochimica Polonica; 2015, 62, 1; 133-137
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children
Autorzy:: Kotłowska-Kmieć, Aldona
Bąkowska, Alicja
Szarszewski, Adam
Kamińska, Barbara
Łuczak, Grażyna
Radys, Wojciech
Landowski, Piotr
Brodzicki, Jacek
Korzon, Maria
Liberek, Anna
Powiązania:: https://bibliotekanauki.pl/articles/1040535.pdf
Data publikacji:: 2009
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: T cell
H. pylori
FasL
Fas
apoptosis
lymphocyte
Opis:: The pathomechanism of Helicobacter pylori action upon gastric mucosa and its role in the pathogenesis of gastritis have not been fully elucidated. The aim of this study was to evaluate the most prevalent lymphocyte subpopulations of the gastric mucosa in gastritis in children, as well as to evaluate the expression of Fas and Fas ligand receptors (FasL), periapoptotic markers of gastric mucosa lymphocytes before and after H. pylori eradication. Forty nine patients aged 6 to 17 years, investigated due to chronic abdominal pain, were studied. The obtained tissue samples were analysed by immunohistochemistry. Different lymphocyte subsets were quantified on the basis of surface antigen expression (CD3, CD4, CD8, CD20), secreted cytokines (IL-4, IL-6, IFNγ) and Fas and FasL proteins in the gastric mucosa. B and T helper lymphocytes were found to play a major role in the inflammatory infiltration in the gastric mucosa in children during H. pylori infection. Their expression was found to decrease after eradication. The enhanced expression of Fas receptor on lymphocytes before treatment and a decrease of this expression after eradication of H. pylori were shown. It was demonstrated that there is a correlation between CD4 and Fas receptor expression that may induce apoptosis of the helper lymphocytes in infected children.
Źródło:: Acta Biochimica Polonica; 2009, 56, 3; 433-438
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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