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    Wyświetlanie 1-4 z 4
    Tytuł:
    Polish Artificial Heart - new coatings, technology, diagnostics
    Autorzy:
    Sarna, J.
    Kustosz, R.
    Major, R.
    Lackner, J.
    Major, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/200025.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    pulsed laser deposition
    microstructure
    cell adhesion
    Opis:
    Since 1991, the Foundation for Cardiac Surgery Development in Zabrze has been implementing research on the artificial heart. In 1995, an artificial ventricle, POLVAD, was implanted to a patient, and in 1998, the prototype of a clinical controller, POLPDU-401, was created. A further development of the studies on an implantable artificial heart requires an integrated approach and an application of advanced methods of materials sciences in order to develop new materials suitable for the contact with blood, as well as to apply a multilateral biomedical diagnostics in hydrodynamic conditions. The estimation of the cell–material interaction plays an important role in the biomaterial design. An analysis of the influence of the carbon content in titanium nitride on the biological and biophysical properties of biomaterial coatings was studied. The cell-material reactions were considered in dynamic and static conditions. Three groups of materials were under examinations – titanium nitride (TiN), as well as titanium carbonitride with a low and high carbon content – of which the best properties were observed for TiN. We found a strong influence of the stoichiometry of TiN (atomic ratio of Ti/N) on the biocompatibility. A non-stoichiometric TiN could have a negative influence on the surrounding tissue.
    Źródło:
    Bulletin of the Polish Academy of Sciences. Technical Sciences; 2010, 58, 2; 329-335
    0239-7528
    Pojawia się w:
    Bulletin of the Polish Academy of Sciences. Technical Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Migration channels produced by laser ablation for substrate endothelialization
    Autorzy:
    Major, R.
    Maksymow, K.
    Marczak, J.
    Lackner, J.
    Kot, M.
    Major, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/201285.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    inorganic coatings
    pulsed laser ablation
    tissue scaffold
    endothelial cells migration
    Opis:
    Seeding of cells on functional, biocompatible scaffolds is a crucial step in achievement the desired engineered tissue. In the present study, a pulsed laser modification onto inorganic substrate was made to promote endothelium cells migration and spread. Presented scaffolds were fabricated on carbon and titanium based coatings. Fabricated films provided very good mechanical properties together with a chemical stability preservation. The substrate modification consisted of grid-like template fabrication of micrometer size meshes. The microstructure analysis of laser traces revealed the grain size increase in the zone of laser beam interaction, which exerts an influence on a surface topography. Endothelium cells locomotion was observed within 10 day time period. As a result it was shown that the modified area enhanced cells adhesion with a preferred static behavior. The performed research work improved our understanding on the pulsed laser ablation process and template size influence on cells spatial arrangement. It constituted an important step towards fabrication of inorganic, biocompatible scaffolds for successful substrate endothelialization.
    Źródło:
    Bulletin of the Polish Academy of Sciences. Technical Sciences; 2012, 60, 2; 337-342
    0239-7528
    Pojawia się w:
    Bulletin of the Polish Academy of Sciences. Technical Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mechanisms for self-assembling topography formation in low-temperature vacuum deposition of inorganic coatings on polymer surfaces
    Autorzy:
    Lackner, J.
    Waldhauser, W.
    Alamanou, A.
    Teichert, C.
    Schmied, F.
    Major, L.
    Major, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/200047.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    topography
    roughness
    coatings
    pulsed laser deposition
    magnetron sputtering
    polymers
    Opis:
    Functionalization of surfaces is an important task for nanotechnology to add specially designed physico-chemical properties to materials. Besides chemical modification of surfaces, physical adaptations gain increasing interest. Thus, understanding the influences of film deposition on surface topography formation is the basis for future developments. For physical or chemical vapour deposited (PVD, CVD) films, structure zone models were developed, clearly showing the influences of temperature and vapour energy and, thus, surface and bulk diffusion on film structures based on four different structure zones. Generally, similar zones are also found in PVD coatings on polymeric substrates; However, due to restrictions in coating temperatures due to the thermal resistance of most polymers, the coating temperature is restricted to mostly 50°C, excluding thermal activation of at least surface diffusion of inorganic materials (metals and their nitrides, oxides, carbides, etc.) and resulting in columnar growth with dome-shaped column tops. Additionally, the high difference in mechanical properties between “stiff” inorganic coatings and “flexible” polymers implicates stress-induced growth phenomena, resulting in wrinkling, cracking and finally the formation of a superseding structure, depending on substrate and film materials and the vapour energy of the deposition method.
    Źródło:
    Bulletin of the Polish Academy of Sciences. Technical Sciences; 2010, 58, 2; 281-294
    0239-7528
    Pojawia się w:
    Bulletin of the Polish Academy of Sciences. Technical Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Initial in vivo biocompatybility evaluation of biomaterials used in the new biomimetic heart valve
    Autorzy:
    Gonsior, M.
    Zawidlak-Węgrzyńska, B.
    Janiczak, K.
    Gonsior, D.
    Kustosz, R.
    Major, R.
    Lackner, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/283829.pdf
    Data publikacji:
    2018
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    biomaterials
    polyurethane
    biocompatibility
    Źródło:
    Engineering of Biomaterials; 2018, 21, 148; 81
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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