- Tytuł:
-
Efficacy of albendazole against Trichinella pseudospiralis and Trichinella spiralis in mice
Wplyw albendazolu na przebieg zakazenia Trichinella pseudospiralis i Trichinella spiralis u myszy - Autorzy:
-
Bany, J
Lach, J.
Golinska, Z. - Powiązania:
- https://bibliotekanauki.pl/articles/838080.pdf
- Data publikacji:
- 1992
- Wydawca:
- Polskie Towarzystwo Parazytologiczne
- Tematy:
-
Trichinella pseudospiralis
zwierzeta doswiadczalne
Trichinella spiralis
parazytologia
albendazol
myszy
nicienie
pasozyty
inwazja pasozytnicza
Trichinellidae - Opis:
- Albendazole (Smith Kline, Beecham) in a dose of 20 mg/kg/day was given to B6C3F₁ mice exposed to 300 larvae of T. pseudospiralis or T. spiralis. The drug was introduced on days 2, 3 and 4; or 4, 5 and 6; or 18, 19 and 20 after infection. It limited the intensity of intestinal and muscle phases of trichinellosis. Given at the stage of maturation of adult forms and production of new-born larvae, the drug caused almost total elimination of both species from the intestines of mice and a decrease in the numbers of muscle larvae, with a tendency towards a greater reduction of larvae and adults of T. pseudospiralis. The drug did not change the course of infection when given at the phase of infectiveness of larvae.
- Źródło:
-
Annals of Parasitology; 1992, 38, 3-4; 143-146
0043-5163 - Pojawia się w:
- Annals of Parasitology
- Dostawca treści:
- Biblioteka Nauki
Artykuł