- Tytuł:
-
Szczepionka przeciwko afrykańskiemu pomorowi świń - gdzie jesteśmy i dokąd zmierzamy
Vaccine against African swine fever – where are we and where are we going? - Autorzy:
-
Pomorska-Mól, Małgorzata
Turlewicz-Podbielska, Hanna
Augustyniak, Agata
Kucińska, Izabela - Powiązania:
- https://bibliotekanauki.pl/articles/22395508.pdf
- Data publikacji:
- 2022
- Wydawca:
- Krajowa Izba Lekarsko-Weterynaryjna
- Tematy:
-
trzoda chlewna
choroby wirusowe
immunoprofilaktyka
szczepienia ochronne
szczepionki wektorowe
szczepionki podjednostkowe
strategia DIVA
choroby zwierząt
afrykański pomór świń
bezpieczeństwo szczepionek
szczepionki żywe atenuowane
vaccine
African swine fever
immunoprophylaxis - Opis:
- African swine fever (ASF), is a viral disease of pigs and wild boar that is usually deadly. There are neither vaccines nor cures. African swine fever has got a significant negative impact on the global pig industry. The disease control is based on ensuring biosecurity, early diagnosis and culling pig herds with ASFV‐infected animals. However, in view of the ease with which ASFV spreads, its high resistance to environmental conditions and the many difficulties related to the introduction of effective specific immunoprophylaxis, this process is extremely difficult. Despite encountering problems such as lack of an animal model other than the natural host, lack of an effective continuous cell line for the isolation and propagation of ASFV, a risk of reversion to virulence, or inability to differentiate infected animals from vaccinated ones, scientists do not stop trying to design an effective vaccine. Recent approaches to ASF vaccine construction have focused on the development of modified live vaccines by targeted gene deletion from different isolates or of subunit vaccines. Here, we discuss current scientific advances and technological progress in this issue. The design of a safe and effective vaccine against ASFV seems to be achievable, nevertheless, a commercial vaccine is unlikely to appear within the next few years.
- Źródło:
-
Życie Weterynaryjne; 2022, 97, 06; 378-384
0137-6810 - Pojawia się w:
- Życie Weterynaryjne
- Dostawca treści:
- Biblioteka Nauki
Artykuł