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Wyszukujesz frazę "Wiśniewska-Wrona, Maria" wg kryterium: Autor


Wyświetlanie 1-7 z 7
Tytuł:
Polymer biocomposites used in bedsores treatment
Autorzy:
Wiśniewska-Wrona, Maria
Kucharska, Magdalena
Kardas, Iwona
Bodek, Andrzej
Bodek, Henryka
Powiązania:
https://bibliotekanauki.pl/articles/1035413.pdf
Data publikacji:
2011
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
bacteriostatic agent
bedsore
dressing
film
polymeric biocomposites
Opis:
Investigations are presented in the preparation of composite dressing material based on two biopolymers -chitosan and sodium alginate with the addition of sulfanilamide as medication designed for the healing of bedsores. The dressing was prepared in the form of film. The biopolymers used in the construction of the film make the dressing biodegradable and resorbable in the wound’s environment. Mechanical properties of the film were tested: thickness, extension strength, tenacity and elongation at maximum stress The ability of the material to match the wound was examined, too, as well as the transmission of water vapor. Sulfanilamide as bacteriostatic agent was added to the prepared composites. Mechanical and sorption properties of the composite dressings with addition of the active substance depend largely on their composition. The sorption properties were tested before and after addition of the medication .The release of the medication is intricate and proceeds according to kinetics of first order. Susceptibility of the composite materials to hydrolytic and enzymatic degradation was assessed.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2011, 16; 111-120
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
POTENTIAL USE OF CHITOSAN – BASED MATERIALE IN MEDICINE
Autorzy:
Kucharska, Magdalena
Ciechańska, Danuta
Niekraszewicz, Antoni
Wiśniewska-Wrona, Maria
Kardas, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/1035560.pdf
Data publikacji:
2010
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
biomaterials
medicine
polysaccharides
Opis:
Polysaccharides are macromolecular polymers that manifest ability toward the forming of fibres, film and coatings. Some of their specific properties like biodegradability and biocompatibility make them suitable for medical application. Chitin, chitosan and alginates are basic polymers mostly used in the preparation of medical biomaterials. In the Institute of Biopolymers and Chemical Fibres (IBWCh) multidirectional investigations are in full swing concerned with the use medical of polysaccharides and their various useful forms. The research includes amongst: multifunctional dressing materials, implants and other polysaccharide biomaterials.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2010, 15; 169-176
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of oligochitosans in akt kinase regulation
Autorzy:
Ignacak, Jan
Wiśniewska-Wrona, Maria
Dulińska-Litewka, Joanna
Pałka, Iwona
Kucharska, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1034912.pdf
Data publikacji:
2015
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
Akt kinase – PKB
EAT cells proliferation
HIF-1 factor.
M2 pyruvate kinase
Opis:
Among characteristic properties of cancers, there is their increased glycolytic activity.Contrary to normal cells, neoplastic cells use anaerobic glycolysis, even when a sufficient amount of oxygen is available. The intensity of the process is associated with a considerable demand for energy in the form of ATP. Akt, which - acting through the mTOR pathway - activates the HIF-1 factor, which in turn activates hexokinase that participates in glucose phosphorylation, stimulates the transport of glucose to cells via increasing glucose transporters (GLUT) and activates lactate dehydrogenase (which transforms pyruvate to lactate). Chitosan, as well as products of its degradation - oligochitosans - contribute to inhibiting the activity of the Akt kinase, and thus contribute to inhibiting excessive glycolytic activity of Ehrlich ascites tumor (EAT) cells and to decreasing proliferation of these cells.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 73-81
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Inhibition of ehrlich ascites tumour (eat) cells proliferation through chitosan-mediated regulation of activity of the akt pathway
Autorzy:
Ignacak, Jan
Wiśniewska-Wrona, Maria
Dulińska-Litewka, Joanna
Pałka, Iwona
Kucharska, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1035195.pdf
Data publikacji:
2014
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
Akt kinase - PKB
EAT cells proliferation
M2 pyruvate kinase
chitosan
Opis:
Isoenzyme M2 pyruvate kinase, which is a marker of cancer transformation, can take both tetramer (cytosol) and dimer (nucleus) forms. The former is responsible for ATP synthesis, and the latter demonstrates histone H1 kinase activity. Regulation of the expression of pyruvate kinase through which Akt controls the expression of genes involved in Ehrlich ascites tumour (EAT) cell proliferation, migration and death, also involves cross-talk with the other signalling pathways, transcription factors and co-regulatory proteins such as β-catenin and c-Myc. Treatment of EAT cells with chitosans significantly reduced their proliferation (by 45-60%), expression of nuclear β-catenin, c-Myc as well as cell migration. After 48–72 hours of treatment of the cell with oligochitosans, lower levels of p-Akt were detected. Simultaneously, decreased expression of isoenzyme M2 PK protein levels was observed. The dimeric form (nucleus) can participate in H1 histone phosphorylation, which contributes to increased EAT cell proliferation.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2014, 19; 33-40
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of chitosan in akt kinase regulation activity
Autorzy:
Ignacak, Jan
Wiśniewska-Wrona, Maria
Dulińska-Litewka, Joanna
Pałka, Iwona
Kucharska, Magdalena
Kazimierski, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1034695.pdf
Data publikacji:
2016
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
Akt kinase (PKB)
M2 pyruvate kinase
cells migration
metalloproteinases
Opis:
A decrease in migration of tumor cells incubated with the investigated chitosan preparations was correlated with a decreased activity of MMP-2 and MMP-9 metalloproteinases, what significantly affected inhibition of tumor cell proliferation. In the investigations of the effects of various chitosan preparations on expression of PCNA, Akt and β-catenin in the normal human 184A1 cells and in breast carcinoma MCF7 cells evaluated at the protein level, significant differences in inhibition of expression of selected genes were noted in the tumor cells. Similarly as in the case of human cells, in mouse cells, the differences in expression of the investigated genes involved solely the Ehrlich carcinoma cells. In the presence of the investigated chitosan preparations, there was observed inhibition of expression of the N-cadherin, β-catenin, Akt and PCNA genes. In case of p21 protein, its level increased, similarly as in the human breast carcinoma cells, what may also be related to phosphorylation of the protein, its capture by the cytosol and prolonging its half-life as compared to the non-phosphorylated form. In case of the normal human 181A1 cells and mouse CRL 1636 cells, no significant alterations were noted in expression of the investigated genes in presence of the employed chitosan preparations.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 73-82
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Advanced cellulosic materials
Autorzy:
Brzoza-Malczewska, Kinga
Kucharska, Magdalena
Wiśniewska-Wrona, Maria
Guzińska, Krystyna
Jóźwicka, Jolanta
Bacciarelli-Ulacha, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1034809.pdf
Data publikacji:
2015
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
cellulosicproducts
chitosan
complex chitosan/alginate
nanoparticles
Opis:
Aim of the work was to prepare a method of producing chitosan and chitosan-alginate nanoparticles designed for the modification of textile cellulosic products in hygiene and medical application. Spectrophotometry was used in the estimation of the prepared nanoparticles; analyzed, too, was the particle size and antibacterial and antifungal activity.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 7-17
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Haemostatic, resorbable dressing of natural polymers - hemoguard
Autorzy:
Kucharska, Magdalena
Wiśniewska-Wrona, Maria
Brzoza-Malczewska, Kinga
Struszczyk, Marcin H
Cichecka, Magdalena
Wilbik-Hałgas, Bożena
Rybak, Zbigniew
Szymonowicz, Maria
Paluch, Danuta
Guzińska, Krystyna
Kaźmierczak, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/1035068.pdf
Data publikacji:
2015
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
biological and useful properties
haemostatic
natural polymers
Opis:
Investigations are presented in the preparation of a first aid haemostatic dressing that would exhibit an adequate haemostatic capacity in injuries and surgical wounds, an antibacterial activity to prevent primary and secondary infections, and offer safety in use
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 130-141
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-7 z 7

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