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Wyszukujesz frazę "head and neck" wg kryterium: Temat


Wyświetlanie 1-4 z 4
Tytuł:
Application of cone beam computed tomography in ENT and reconstructive head and neck surgery – literature review and own experience
Autorzy:
Piotrowska-Seweryn, Agnieszka
Krakowczyk, Łukasz
Maciejewski, Adam
Kaniszewska-Dorsz, Żaneta
Markowski, Jarosław
Pietrauszka, Kornelia
Goroszkiewicz, Karolina
Powiązania:
https://bibliotekanauki.pl/articles/1399645.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
computed tomography
ENT
free flap
head and neck
reconstruction
Opis:
CBCT is a relatively new diagnostic imaging method. It was first used in 1982 at the Mayo Clinic Biodynamics Research Laboratory [1], and has been commercially used in dentistry since 2001. It differs from multidetector computed tomography in terms of implementation technique and some parameters. A low dose of radiation is its greatest advantage, thanks to which many specialists, including ENT doctors and reconstructive surgeons, are more willing to use it. In otorhinolaryngology, CBCT is applied in pre- and perioperative diagnostics in both rhinology and otology. In reconstructive surgery, CBCT facilitates precise planning of the flap and intraoperatively allows a perfect match of the reconstructed tissue elements. In the article, the authors present current information on CBCT in ENT obtained on the basis of a review of Polish and foreign literature and share their own experience in its application in reconstructive surgery within the craniofacial region.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 3; 1-7
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microvascular nose reconstruction after extended tumor resection
Autorzy:
Krakowczyk, Łukasz
Szymczyk, Cezary
Wierzgoń, Janusz
Oleś, Krzysztof
Smyczek, Dominika
Ulczok, Rafał
Donocik, Karolina
Hadasik, Grzegorz
Piotrowska, Agnieszka
Maciejewski, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1391900.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
free flaps
head and neck
nasal cancer
nasal reconstruction
Opis:
Introduction: The nose is the central and probably the most important organ of the face. In view of the three-dimensional shape and variety of tissues, reconstructive surgery after tumor resection in this anatomical region requires the surgeon’s knowledge of anatomy. Materials and Method: In the years 2010–2019, 48 patients were treated in the Oncological and Reconstructive Surgery Clinic for extended nasal tumors, which required the use of free microvascular flaps after resection for functional and aesthetic supply of anatomical structures of the nose. Results: In 48 patients, a total of 92 free microvascular flaps were used for nasal reconstruction including: radial forearm free flap in 24 patients, radial forearm free flap with radial bone in 14 patients, auricular free flap in 16 patients, radial forearm free flap in combination with auricle free flap in 7 patients, double auricular free flap in 6 patients, radial forearm free flap in combination with double auricular free flap in 4 patients. Total necrosis of the free flap was noted in 4 cases, partial in 6 patients. Conclusions: The presented surgical techniques using microvascular free flaps constitute a recognized method of treatment and should be used in everyday surgeon practice. The results demonstrated in this article allow to obtain optimal functional and aesthetic effects.
Źródło:
Polish Journal of Surgery; 2020, 92, 5; 1-7
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of MGMT polymorphisms rs12917 and rs11016879 in head and neck cancer risk and prognosis
Autorzy:
Kiczmer, Paweł
Prawdzic Seńkowska, Alicja
Strzelczyk, Joanna
Szydło, Błażej
Biernacki, Krzysztof
Osadnik, Tadeusz
Krakowczyk, Łukasz
Ostrowska, Zofia
Powiązania:
https://bibliotekanauki.pl/articles/1038528.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
MGMT
head and neck cancer
polymorphism
rs12917
rs11016879
Opis:
Head and neck squamous cell carcinoma (HNSCC) is one of the leading cancers by incidence worldwide. The risk of these cancers is strictly associated with alkylation factors present in tobacco smoke. The crucial role in preventing DNA alkylation is played by O6-methylguanine-DNA methyltransferase (MGMT). Dysfunction or lack of MGMT is associated with an increased risk of cancer. The aim of the study was to assess the influence of MGMT polymorphisms: rs12917 and rs11016879 on HNSCC risk and course. The study consisted of 69 HNSCC patients and 242 healthy individuals. Case samples were taken from resected tumour tissue. The control group comprised samples of epithelial cells collected from mucous membranes using swabs. DNA samples were genotyped by employing the 5' nuclease assay for allelic discrimination using TaqMan SNP Genotyping Assays. The significance between distributions of genotypes and alleles was tested using Pearson's χ2 test analysis. Our results indicated that the MGMT rs12917 TT genotype increases the risk of HNSCC. The MGMT rs11016879 AG genotype and A allele were associated with increased HNSCC risk. We noted higher risk of nodal metastasis in rs11016879 AA homozygotes. Mechanisms leading to MGMT enzymatic defect are unknown and hence further studies need to be carried out. Our data suggest that the examined polymorphisms may be considered as potential prognostic factors for HNSCC risk and outcome. Further studies are necessary to verify our results.
Źródło:
Acta Biochimica Polonica; 2018, 65, 1; 87-92
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Virtual surgical planning and cone beam computed tomography in reconstruction of head and neck tumors – pilot study
Autorzy:
Krakowczyk, Łukasz
Piotrowska-Seweryn, Agnieszka
Szymczyk, Cezary
Wierzgoń, Janusz
Oleś, Krzysztof
Ulczok, Rafał
Donocik, Karolina
Dowgierd, Krzysztof
Maciejewski, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1397270.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
cone beam computed tomography
free flap
head and neck
reconstruction
virtual surgical planning
Opis:
Introduction: The aim of the study was to prove that a combination of visual surgical planning (VSP) and cone beam computed tomography (CBCT) is an optimal technique in fibular free flap reconstructions after complex tumor resections in the head and neck region and that it leads to better functional and aesthetic outcomes. Material and method: Six patients (3 females, 3 males) with head and neck tumors were included in the study. The region concerned midface in 2 cases and mandible in 4 patients. On the basis of computed tomography of the head, fibular free flap (FFF) reconstruction was planned with the VSP technique. The 3D-printed models were prepared. At the beginning of the operation and a few minutes after the reconstruction, an xCAT CBCT by XORAN was performed. Minor corrections of the angles of the reconstructed bony parts were made where needed. The time of the operation was assessed for each case. Functional and cosmetic results were evaluated in a 1-year follow-up. Results: The mean time of operation was 6 hours and 48 minutes, which was approximately 1hour and 40 minutes less than standard reconstructive surgery. Functional recovery was achieved in all patients. Aesthetic result was unsatisfactory for 2 patients due to insufficient soft tissue masses of FFF. Conclusions: The authors claim that intraoperative CBCT imaging, regardless of the cost, improves the accuracy of aesthetic outcome of reconstructive surgeries based on VSP, especially in the region of the midface and the mandible. Further studies on a higher number of subjects are required.
Źródło:
Polish Journal of Otolaryngology; 2021, 75, 2; 28-33
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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