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    Wyświetlanie 1-6 z 6
    Tytuł:
    The phenomenon of apoptosis in the course of experimental trichinellosis in mice
    Autorzy:
    Karmanska, K
    Houszka, M.
    Piekarska, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/837779.pdf
    Data publikacji:
    2000
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    mouse
    mice
    trichinellosis
    larva
    apoptosis
    Trichinella spiralis
    Opis:
    Mice infected with 200 Trichinella spiralis larvae were killed at 3-69 days post infection (dpi) and the jejunum and masseter muscles were sectioned in a cryostat and examined in the Tuneli method with "In situ Cell Detected Kid POD" of Boehringer-Mannheim. Data concering the exact localization and dynamie of apoptic cells in both organs are presented. The authors conclude that apoptosis plays a important role in the pathogenesis of trichinellosis.
    Źródło:
    Annals of Parasitology; 2000, 46, 1
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of adriamycin on the CD4 and CD8 cells in the course of trichinellosis in mice
    Autorzy:
    Karmanska, K
    Houszka, M.
    Mista, D.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/837229.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    mouse
    mice
    cell
    trichinellosis
    adriamycin
    histopathology
    Opis:
    The effect of adriamycin on the behaviour of CD4⁺ and CD8⁺ cells in the course of trichinellosis in mice has been studied. The animals infected with 200 larvae per mouse were administered intraperitoneally adriamycin (Adriblastin from Farmitalia) at 1st and 28th day post infection (dpi), in a dosis of 0.2 mg. The mice were killed weakly for 6 weeks and then at the 60th dpi. The examinations were made on histologic sections from the spleen, mesenteric lymph node, jejunum and masseter muscle using immunofluorescent and immunoenzymatic methods with monoclonal antibody. The mice receiving adriamycin exhibited more CD8⁺ cells in the intestinal mucosa and by the end of the experiment also in the muscles in comparison with the control animals, which, however, did not affect the course of the infection.
    Źródło:
    Annals of Parasitology; 1994, 40, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The cells observed inside capsules of larvae in the course of experimental trichinellosis in mice
    Autorzy:
    Karmanska, K
    Houszka, M
    Widyma, A
    Powiązania:
    https://bibliotekanauki.pl/articles/838158.pdf
    Data publikacji:
    1997
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    immunoenzymatic method
    larva capsule
    infection
    muscle
    mouse
    mice
    cell
    macrophage
    trichinellosis
    monoclonal antibody
    Opis:
    In the course of trichinellosis in mice the numerous cells inside larval capsules were observed. Beginning on 14 day post infection (dpi) they were seen in about 7% of infected muscles fibers but at 21 dpi the percentage of capsules with the cells amounted to 77. In the next stage of infection the number of capsules containing cells continued to increase and reach almost 100% at 60 dpi. The identification of the cells was carried out by the indirect immunoenzymatic method using anti-CD4⁺, anti-CD8⁺ and anti-macrophage (Mac-1 antigen) monoclonal antibodies. In course of observation the level of CD4⁺ cells decreased from 11.3 to 0.7, of CD8⁺ from 17.7 to 3.0 and of macrophages from 71.0 to 23.1 %. The most numerous CD4⁺ cells were seen at 14 dpi while the CD8⁺ and macrophages at 21 dpi. Beginning on 28 dpi negatively reacting cells inside larval capsules were also observed. The number of these cells increased from 23.8 to 73.2% at 60 dpi and their identification requires further investigations. The role and the function of all these cells are discussed.
    Źródło:
    Annals of Parasitology; 1997, 43, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Attempts of modification of apoptosis in the course of experimental trichinellosis in mice
    Autorzy:
    Karmanska, K
    Piekarska, J.
    Widyma, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/841587.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    inflammatory infiltration
    parasite
    mouse
    mice
    trichinellosis
    jejunum mucosa
    experimental trichinellosis
    apoptosis
    modification
    Opis:
    The influence of the some immunomodulators (PHA-P, TFX and dexamethasone) on the process of apoptosis, occurring in the course of trichinellosis in mice, has been studied. It has been found that PHA-P activates this process in the jejunum mucosa and prolongs it in the muscular inflammatory infiltration, whereas TFX has no influence and dexamethasone distinctly decreases the level of the apoptotic cells. The number of the intestinal trichinae on the successive days of infection was similar in all groups of animals, however, the number of the muscular larvae in the groups receiving immunostimulators was much lower and in the group treated with dexamethasone - a little higher than that in control. As in mice receiving PHA-P and TFX, the cellular inflammatory infiltration in the muscles was larger than that in control, and in the group to which dexamethasone was administrated - smaller, the authors think that it was extensiveness of the infiltration and not the level of the apoptotic cells that influenced the number of the outliving larvae.
    Źródło:
    Annals of Parasitology; 2001, 47, 2
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Macrophages during infection with Trichinella spiralis in mice
    Autorzy:
    Karmanska, K
    Houszka, M.
    Widyma, A.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/837069.pdf
    Data publikacji:
    1997
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    larva capsule
    immunoenzymatic technique
    mouse
    infection
    mice
    trichinellosis
    macrophage
    monoclonal antibody
    Trichinella spiralis
    muscle tissue
    Opis:
    Behaviour of macrophages in experimental mice trichinellosis, was investigated using the immunoenzymatic technique with monooclonal antibodies CD11b/CD18 within the framework of avidin-biotin-DAB. The maximum and earliest mobilization of macrophages 7 day post infection (dpi) was observed in the lamina propria of the intestinal mucosa. The highest level of macrophages in the muscles tissue was noted on day 21 of infection, however as early as in 28 dpi, their maximum level was observed inside the larval capsules. They line, especially between 35-42 dpi internal capsule surphace.
    Źródło:
    Annals of Parasitology; 1997, 43, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CD4 and CD8 cells in mice infected with Trichinella spiralis and treated with cyclosporine A
    Autorzy:
    Karmanska, K
    Houszka, M.
    Mista, D.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/836501.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    immunoenzymatic method
    mouse
    infection
    mice
    cell
    T lymphocyte
    immunofluorescent method
    cyclosporin A
    larva
    Trichinella spiralis
    Opis:
    Studies were undertaken to evaluate by parasitological techniques the course of intestinal and muscular invasions in mice infected with Trichinella spiralis and treated with TFX-Thymomodulin (TFX-Th). Studies were conducted on 120 mice of BALB/c and SWISS strains, infected each with a mean invasive dose of 300 T. spiralis larvae. TFX-Th (Thymoorgan GmbH Pharmazie Co. KG, Vienenburg, Germany) was administered subcutaneously at 30 mg/kg body weight. Depending upon duration of TFX-Th administration and stages of intestinal and muscular invasions, three experiments were distinguished in the study. The results indicated that TFX-Th promoted eradication of larvae from muscles, whether administered at the early of the late stage of T. spiralis invasion.
    Źródło:
    Annals of Parasitology; 1994, 40, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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