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    Wyświetlanie 1-7 z 7
    Tytuł:
    Przyczyny i konsekwencje zmian w narządzie żucia u osób starszych
    Autorzy:
    Kamińska, Barbara
    Kaczorowska-Bray, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/667550.pdf
    Data publikacji:
    2017
    Wydawca:
    Wydawnictwo Uniwersytetu Śląskiego
    Opis:
    Causes and Consequences of Changes in Chewing Organ of the ElderlyThe article discusses the phenomena connected with physiological changes occurring in the stomatognathic system of the elderly. It points to their relation with the activities of chewing and swallowing as well as the general state of health and social functioning of older people. The issues addressed in the text are of vital importance not only for dentists and geriatrists, but also for speech therapists and other specialists working with seniors.Key words: gerontologopaedics, stomatognathic system, chewing organ
    Źródło:
    Logopedia Silesiana; 2017, 6; 46-56
    2300-5246
    2391-4297
    Pojawia się w:
    Logopedia Silesiana
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Późna dorosłość z perspektywy logopedii
    Late adulthood from the perspective of speech therapy
    Autorzy:
    Milewski, Stanisław
    Kaczorowska-Bray, Katarzyna
    Kamińska, Barbara
    Powiązania:
    https://bibliotekanauki.pl/articles/952174.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet w Białymstoku. Wydawnictwo Uniwersytetu w Białymstoku
    Tematy:
    late adulthood
    geriatric speech therapy
    gerontological linguistics
    changes in linguistic communication
    Opis:
    Observed demographic changes mean that we are becoming a ‘greying society.’ This makes it necessary to introduce new curriculum content in the vocational training of speech therapists and creates a need for specialists in the area of therapy and functional assistance of seniors. At the same time, this indicates the need for conducting extensive studies in the field of gerontological linguistics, concerning the particularities of speech related to age as well as the specific features of communication with the elderly. In this speech the authors would like to discuss one of the directions of research on language phenomena related to old age, i.e. research on the particular manner of communication of those in the senior’s close environment (family, doctors, therapists, among others) with the senior. The style of communication with a person of senior age, being a result of social stereotypes of elderly people, may increase their discomfort and indicate paternalistic and condescending treatment of those in the highest age group. This may even be a sign of ageism, i.e. social discrimination based on people’s age.
    Źródło:
    Pogranicze. Studia Społeczne; 2016, 28
    1230-2392
    Pojawia się w:
    Pogranicze. Studia Społeczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Peripheral regulatory T cells and anti-inflammatory cytokines in children with juvenile idiopathic arthritis
    Autorzy:
    Sznurkowska, Katarzyna
    Boćkowska, Małgorzata
    Zieliński, Maciej
    Plata-Nazar, Katarzyna
    Trzonkowski, Piotr
    Liberek, Anna
    Kamińska, Barbara
    Szlagatys-Sidorkiewicz, Agnieszka
    Powiązania:
    https://bibliotekanauki.pl/articles/1038532.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Tregs
    IL-10
    TGF-β1
    juvenile idiopathic arthritis
    Opis:
    Background: Juvenile idiopathic arthritis (JIA) is a chronic, heterogenous inflammatory disease of unclear pathogenesis. JIA is hypothesized to be linked to a defective immune regulation. Anti-inflammatory cytokines belong to the best known regulatory factors. T-regulatory cells are a crucial cellular component of immune tolerance. One of their functions is synthesis of interleukin 10 (IL-10) and transforming growth factor beta1 (TGF-β1). The aim of this study was to determine the proportion of T-regulatory cells (CD4+CD25highFOXP3+) in peripheral blood, and serum levels of TGF-β1 and IL-10 in patients with JIA. Methods: The study included 25 patients with newly diagnosed JIA: oligoarthritis (n=17) and polyarthritis (n=8). The control group was comprised of 17 healthy children. CD4+CD25highFOXP3+ T cells in peripheral blood were quantified by means of three-color flow cytometry. Serum concentrations of TGF-β1 and IL-10 were estimated with ELISA. Results: The proportion of peripheral CD4+CD25highFOXP3+ cells in patients with JIA was significantly higher than in the controls (p=0.04). The two groups did not differ significantly in terms of their TGF-β1 and IL-10 concentrations. Conclusions: At the time of diagnosis, children with JIA presented with an elevated proportion of T-regulatory cells (CD4+CD25highFOXP3+) in peripheral blood. Anti-inflammatory cytokines, IL-10 and TGF-β1, are not upregulated in the serum of patients with JIA, and therefore should not be considered as biomarkers of this condition.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 1; 119-123
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fecal lactoferrin, a marker of intestinal inflammation in children with inflammatory bowel disease
    Autorzy:
    Borkowska, Anna
    Liberek, Anna
    Łuczak, Grażyna
    Jankowska, Agnieszka
    Plata-Nazar, Katarzyna
    Korzon, Maria
    Kamińska, Barbara
    Powiązania:
    https://bibliotekanauki.pl/articles/1039002.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    fecal lactoferrin
    inflammatory bowel disease
    children
    Opis:
    The aim of this study was to analyze the usefulness of fecal lactoferrin in the diagnosis and monitoring of inflammatory bowel disease (IBD) in children. The study included 52 children with IBD (24 with Crohn's disease and 28 with ulcerative colitis) aged between 0.92 and 18 years, and 41 IBD-free controls of similar age. Fecal concentration of lactoferrin was determined with a quantitative immunoenzymatic test. Fecal concentration of lactoferrin in children with IBD was significantly higher than in the controls. The cut-off value of fecal lactoferrin concentration optimally distinguishing between the children with IBD and the controls was identified as 13 μg/g. The sensitivity and specificity of this cut-off value equaled 80.7% and 92.7%, respectively, and its positive and negative prognostic values were 96.8% and 63.3%, respectively. Patients diagnosed with moderate Crohn's disease had significantly higher fecal concentrations of lactoferrin than children with the mild or inactive disease. Similarly, children with moderate ulcerative colitis showed significantly higher fecal concentrations of lactoferrin than individuals with the mild condition. No significant relationship was found between the fecal concentration of lactoferrin and the severity of endoscopic lesions. Patients with IBD and a positive result of fecal occult blood test were characterized by significantly higher concentrations of lactoferrin than the individuals with IBD and a negative result of this test. In conclusion, fecal concentration of lactoferrin seems to be a useful parameter for diagnosis and monitoring of IBD in children.
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 3; 541-545
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Coexistence of type 1 diabetes mellitus and spinal muscular atrophy in an 8-year-old girl: a case report
    Autorzy:
    Borkowska, Anna
    Jankowska, Agnieszka
    Szlagatys-Sidorkiewicz, Agnieszka
    Sztangierska, Beata
    Liberek, Anna
    Plata-Nazar, Katarzyna
    Kamińska, Barbara
    Powiązania:
    https://bibliotekanauki.pl/articles/1039156.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Spinal muscular atrophy
    diabetes mellitus
    children
    Opis:
    The spinal muscular atrophy is a rare autosomal recessive genetic disease characterized by the progressive loss of muscular strength. In its natural course the disease leads to death. Diabetes mellitus type 1 is an autoimmune metabolic disorder characterized by the disturbed insulin synthesis. This is a case report of an 8-year-old girl suffering from Werdnig Hoffman disease in whom DM1 was diagnosed. The unspecific clinical manifestation and diagnostic difficulties are presented in this paper. To the authors' knowledge, this is the first publication concerning the co-existence of these two medical conditions.
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 1; 167-168
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Graves disease, celiac disease and liver function abnormalities in a patient - clinical manifestation and diagnostic difficulties
    Autorzy:
    Góra-Gębka, Magdalena
    Woźniak, Małgorzata
    Cielecka-Kuszyk, Joanna
    Korpal-Szczyrska, Maria
    Sznurkowska, Katarzyna
    Zagierski, Maciej
    Jankowska, Irena
    Plata-Nazar, Katarzyna
    Kamińska, Barbara
    Liberek, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/1039288.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    autoimmune disease
    Graves' disease
    celiac disease
    liver abnormalities
    children
    Opis:
    Autoimmune diseases due to probable common pathogenesis tend to coexist in some patients. Complex clinical presentation with diverse timing of particular symptoms and sophisticated treatment with numerous side effects, may cause diagnostic difficulties, especially in children. The paper presents diagnostic difficulties and pitfalls in a child with Graves' disease, celiac disease and liver function abnormalities.
    Źródło:
    Acta Biochimica Polonica; 2014, 61, 2; 281-284
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinical parameters of inflammatory bowel disease in children do not correlate with four common polymorphisms of the transforming growth factor β1 gene
    Autorzy:
    Liberek, Anna
    Jakóbkiewicz-Banecka, Joanna
    Kloska, Anna
    Świderska, Joanna
    Kmieć, Zbigniew
    Łuczak, Grażyna
    Wierzbicki, Piotr
    Liberek, Tomasz
    Marek, Krzysztof
    Plata-Nazar, Katarzyna
    Sikorska-Wiśniewska, Grażyna
    Kamińska, Barbara
    Węgrzyn, Grzegorz
    Powiązania:
    https://bibliotekanauki.pl/articles/1039871.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    pediatric patients
    gene polymorphism
    Transforming growth factor β1
    inflammatory bowel disease
    Opis:
    Transforming growth factor β1 (TGF-β1) is a cytokine affecting cell proliferation and development, which also has an immunomodulatory activity. Correlations between polymorphisms of the TGF-β1 gene and clinical parameters of inflammatory bowel disease (IBD) were reported previously in adults. Here, we tested whether such correlations occur in pediatric patients suffering from IBD. One hundred and four pediatric IBD patients were involved in this study. Among them, 36 were diagnosed with Crohn's Disease (CD) and 68 were diagnosed with ulcerative colitis (UC). The control group consisted of 103 children, in which IBD was excluded. TGF-β1 levels were determined in plasma and intestinal mucosa samples. The presence of the TGF β1 protein and the amount of TGF β1 mRNA were estimated in intestinal mucosa by immunohistochemistry and reverse transcription Real-Time PCR, respectively. Four common polymorphisms of the TGF-β1 gene were investigated: -800G/A, -509C/T, 869T/C and 915G/C. No significant correlation between TGF-β1 genotypes and (i) TGF-β1 levels in plasma and tissue samples, (ii) TGF-β1 gene expression efficiency in intestinal mucosa, (iii) IBD clinical parameters and (iv) inflammatory activity could be detected in children suffering from IBD. We conclude that, contrary to previous suggestions, the four common polymorphisms of the TGF-β1 gene do not influence the susceptibility to or clinical parameters of IBD in the tested population of children.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 4; 641-644
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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