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    Tytuł:
    Poziom wiedzy oraz opinie pielęgniarek na temat transplantacji organów
    Level of knowledge and opinions of nurses concerning organ transplants
    Autorzy:
    Makara-Studzinska, M.
    Kowalska, A.J.
    Jakubowska, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/3975.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2012, 18(47), 1
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effectiveness of mixtures with the Fabaceae seeds in broiler chicken feeding
    Efektywność mieszanek z udziałem nasion roślin bobowatych stosowanych w żywieniu kurcząt brojlerów
    Autorzy:
    Osek, M.
    Milczarek, A.
    Klocek, B.
    Turyk, Z.
    Jakubowska, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2197005.pdf
    Data publikacji:
    2013
    Wydawca:
    Uniwersytet Przyrodniczy w Lublinie. Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
    Tematy:
    animal nutrition
    feeding effectiveness
    feed mixture
    Fabaceae
    seed
    broiler chicken
    feeding
    Źródło:
    Annales Universitatis Mariae Curie-Skłodowska. Sectio EE: Zootechnica; 2013, 31, 4; 77-86
    0239-4243
    2083-7399
    Pojawia się w:
    Annales Universitatis Mariae Curie-Skłodowska. Sectio EE: Zootechnica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Electrical bioimpedance in patients after ischemic stroke, a civilization disease
    Autorzy:
    Nalepa, D.
    Czrkowska, M.
    Załuska, W.
    Jakubowska, K.
    Chruściel, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/2082979.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    cerebral stroke
    electrical bioimpedance
    hydration
    Opis:
    Introduction. Ischemic stroke is caused by artery blockage, resulting in damage to brain tissue. A significant factor in the further treatment of a patient is not only the time to reach a specialist centre, but also the state of hydration of the organism. Clinical situations involving the excess or deficiency of water can have extremely serious consequences for the functioning of the body and subsequent stroke-related disorders. One of the increasingly common methods of evaluating the composition of the human body is by electrical bioimpedance. Objective. The aim of the study was to assess the state of human body hydration measured by bioimpedance in patients with an early stage of ischemic stroke. Methods and materials. The examination involved 81 patients with ischemic stroke in the Neurology Department, Subdivision of Stroke Treatment at the Province Specialist Hospital in Lublin, Poland, in 2015. Measurement of the composition and outer and intracellular space of the human body by the Whole Body Bioimpedance (WBIA) method was performed using the Body Composition Monitor (BCM) (Fresenius Medical Care GmbH, Bad Homburg, Germany). Results. A group of patients were been examined with the use of the BIA apparatus three times: on the first, seventh, and tenth day of hospital stay, to determine the level of body hydration. Comparative analysis of data showed that on the first day of hospitalization all the measurements of electrical bioimpedance parameters in the patients were significantly different from those of the control group. In the case of TBW, ECW, ICW, the patients’ scores were significantly higher than those of the control group. Only with respect to the over-hydration index, the patients achieved a significantly lower score than the control group. Conclusions. Assessment of hydration status in patients with a diagnosed stroke indicates a slight dehydration in relation to the control group, but falling within the scope of normovolaemia, according to bioimpedance measurement standards.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 46-50
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Optical emission spectroscopy of plasma streams in PF-1000 experiments
    Autorzy:
    Jakubowska, K.
    Kubkowska, M.
    Skladnik-Sadowska, E.
    Malinowski, K.
    Marchenko, A. K.
    Paduch, M.
    Sadowski, M. J.
    Scholz, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/146628.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    dense plasma focus (DPF)
    optical emission spectroscopy
    deuterium Balmer series
    Ar II lines
    electron density
    Boltzmann plot
    Opis:
    The optical spectroscopy in the visible range was used to determine properties of the dense magnetized plasma generated in the PF-1000, a 1 MJ plasma focus device operating in the Institute of Plasma Physics and Laser Microfusion (IPPLM) in Warsaw, Poland. The experiments were performed in a vacuum chamber pumped out to the basic pressure of 2 x 10.5 hPa. The initial pressure of the pure deuterium filling was 2.9 hPa, while that of the deuterium--argon mixture was 1.07 hPa of D2 and 0.13 hPa of Ar. The deuterium-plasma emission contained the Balmer series (Dalfa, Dbeta and Dgamma) and a few distinct copper (Cu I) lines originating from the inner electrode material. The emission of the deuterium-argon plasma was rich in Ar II lines. The electron density (ne), averaged over line of sight, of order of 1016 cm.3 was calculated on the basis of the Dalfa and Dbeta emission only, because the D�ż line was strongly self-absorbed. A group of the Ar II spectral lines was used to estimate the excitation temperature (Texc = 3 eV) by means of a Boltzmann plot. Additionally, the temporal evolution of the electron density was determined on basis of the Stark broadening of the Dalfa and Dgamma lines.
    Źródło:
    Nukleonika; 2011, 56, 2; 125-129
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of daily diet on ascorbic acid supply to students
    Autorzy:
    Szczuko, M.
    Seidler, T.
    Stachowska, E.
    Safranow, K.
    Olszewska, M.
    Jakubowska, K.
    Gutowska, I.
    Chlubek, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/874326.pdf
    Data publikacji:
    2014
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    human nutrition
    vitamin
    daily diet
    diet
    ascorbic acid
    supply
    plasma
    dietary intake
    student
    Opis:
    Background. Researchers suspect that the accepted adequate ascorbic acid plasma concentration is not being met even after dietary intake of the recommended amount of vitamin C. Current dietary intake recommendation in Poland is 60 mg per day for women and 75 mg per day for man (EAR), while in Western Europe and North America is higher and amounts to 75-90 mg per day. Objective. The paper aimed at studying a correlation between composition of nutrients in daily diet and plasma vitamin C levels in university students. Materials and methods. This study examined diet composition and the nutritional status of ascorbic acid in plasma of 120 university students in Szczecin, Poland. Ascorbic acid was determined in blood plasma using HPLC method. The information concerning diet composition was collected using the method of “7-days food record” prior to blood collection. Results. Plasma ascorbic acid deficiency (<40 μmol/L) was observed in 23% of women and 28% of men. The average plasma ascorbic acid concentration was 48.65 μmol/L in women and 45.61 μmol/L in men. The average intake of vitamin C in women with observed deficiency was average 46.55 mg/day, whereas in men it was 48.56 mg/day. Conclusions. The recommendation of dietary intake of vitamin C in Poland is low in comparison to other countries. Population- based studies are necessary to determine the actual demand for vitamin C in various population groups in Poland.
    Wprowadzenie. Badacze podejrzewają, że przyjęte odpowiednie stężenie kwasu askorbinowego w osoczu nie jest spełnione nawet po spożyciu zalecanej ilości witaminy C. Aktualna norma spożycia witaminy C w Polsce wynosi 60 mg/dzień dla kobiet i 75 mg/dzień dla mężczyzn (EAR), podczas gdy w Europie Zachodniej i Ameryce Północnej jest większa i wynosi 75-90 mg dziennie. Cel badań. Celem pracy było zbadanie korelacji między składnikami pokarmowymi całodziennej racji pokarmowej a witaminą C u studentów. Materiał i metody. Badano skład diety oraz zawartość witaminy C w osoczu 120 studentów ze Szczecina. Stężenie kwasu askorbinowego oznaczano w surowicy krwi za pomocą HPLC. Informacje dotyczące żywienia zebrano stosując metodę 7 dniowego zapisu żywieniowego przed pobraniem krwi. Wyniki. Niedobór kwasu askorbinowego w osoczu (< 40 μmol/L) wystąpił u 23% kobiet i 28% mężczyzn. Średnie stężenie kwasu askorbinowego w osoczu wynosiło 48.65 μmol/L u kobiet i 45,61 μmol/L u mężczyzn. U kobiet, u których stwierdzono niedobór witaminy C, jej średnie spożycie z dietą wynosiło 46,55 mg/dzień, podczas gdy u mężczyzn 48,56 mg/dzień. Wnioski. Zalecana w Polsce norma dziennego spożycia witaminy C jest niska w porównaniu z innymi krajami. Konieczne są badania populacyjne w celu określenia rzeczywistego zapotrzebowania na witaminę C wśród różnych grup społecznych w Polsce.
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 2014, 65, 3
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The oncoprotein HBXIP – its functions and roles in oncogenesis
    Autorzy:
    Grudzinska, M.
    Lomperta, K.
    Jakubowska, K.
    Samocik, P.
    Jarząbek, K.
    Kanczuga-Koda, L.
    Wincewicz, A.
    Koda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918747.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    HBXIP
    survivin
    oncoprotein
    transcription factor
    Opis:
    Nowadays, Hepatitis B X interacting protein (HBXIP) is an object of scientists’ interest worldwide. It is a protein with significant involvement in the development of malignant tumors like breast or ovarian cancer. One of the most important functions of HBXIP is the regulation of cell proliferation, which is related to the progression of a cell cycle. Many studies provide the growing number of evidence that HBXIP plays various important roles, including the regulation of a cell cycle through complexes with survivin, belonging to the inhibitors of apoptosis and interactions with transcriptional factors like STAT4, SP1, TFIID or E2F1. It also has the influence on the promotion of tumor angiogenesis thanks to the association with VEGF and FGF8. Another important role of HBXIP is a reprogramming of glucose metabolism to conditions favorable to growing cancerous cells due to regulating the activation of SCO2 and PDHA1. Furthermore, it impacts on the complement-dependent cytotoxicity, also, HBXIP affects on lipid metabolism through disturbing of metabolic pathways of FAS. According to recent studies, HBXIP can be used as a prognostic biomarker in many tumors, including cervical cancer, ovarian cancer, and esophageal squamous cell carcinoma thanks to the high expression of this protein noted exclusively in these tumor tissues. What is even more interesting, it significantly correlates with clinical attributes like metastasis to lymph nodes or grading and in some cases can potentially be used as the indicator of prognosis of treatment effectiveness. The paper is review through main functions of HBXIP and its possible applications.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 215-222
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinicopathological significance of Epo, EpoR, Ki-67 and Bax expression in colorectal cancer
    Autorzy:
    Lopmerta, K.
    Grudzinska, M.
    Jakubowska, K.
    Samocik, P.
    Kozlowski, L.
    Fudala, A.
    Wincewicz, A
    Koda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918787.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Colon cancer
    erythropoietin
    erythropoietin receptor
    Opis:
    Introduction: Expression of Epo, a glycoprotein secreted by the fetal liver and the adult kidney in response to cellular hypoxia and its receptor have been described in human solid tumors, such as colon and breast cancer. Purpose: Since activation of Epo-EpoR signaling pathway in erythroid progenitor and precursor cells leads to promotion of proliferation and differentiation or prevention of programmed cell death through Bcl-xl and Bcl-2 it was of interest to investigate expression of Epo, EpoR, apoptosis regulator – Bax and marker of proliferating cells - Ki-67 and assess correlation between them, with regard to clinicopathological variables of colorectal cancer. Materials and methods: The correlations between expression of Epo, EpoR, Bax and Ki-67 in colorectal cancer were analyzed in regard to patient age, sex, primary localization, histopathological type, grading, staging and lymph node invasion. Statistical analyses were performed by using the Spearman rank correlation test applying a significance level of p<0,05. Results: Correlation between Bax and EpoR is positive and statistically significant at all groups of patients except group pT1+pT2. Positive correlation between Bax and Epo is statistically significant at following groups of patients: all patients, age 60, age >60, male, female , primary localization in rectum, primary localization in colon, adenocarcinoma, G2, G3. Statistical analysis revealed no significant correlations between expression of neither Ki-67 with Epo nor Ki-67 with EpoR in all groups of patients. Conclusions: Epo seems to be a pleiotropic cytokine, which can exert its biological effect on several cell types, including neoplastic cells. The effect of Epo-EpoR signaling can differ in various cells and conditions.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 112-117
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Correlation of clinico-pathologic data with inflammatory cells infiltration in colorectal cancer
    Autorzy:
    Grudzińska, M.
    Jakubowska, K.
    Kańczuga-Koda, L.
    Kisielewski, W.
    Famulski, W.
    Smereczański, N.M.
    Lomperta, K.
    Płoński, M.A.
    Rogoz-Jezierska, N.
    Koda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918914.pdf
    Data publikacji:
    2020-06-10
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Colorectal cancer
    inflammatory cells
    fibrosis
    Opis:
    Introduction: Colorectal cancer (CRC) is the third most common cancer worldwide. At every phase of cancer development, the inflammatory process has an important impact. Accurate assessment inflammatory cells in the tumour environment in conjunction with clinico-pathologic features can be a relevant prognostic or predictive parameter. Purpose: To analyse inflammatory cell infiltration in CRC tumour mass and correlate with chosen clinico-pathologic parameters. Materials and methods: The study group consisted of 160 patients (64 women, 96 men) diagnosed with colorectal cancer who underwent surgery. Tissue material obtained from routine histopathological diagnosis was stained with H&E and used to assess the type of inflammatory cells in the invasive front and centre of the tumour. Results were subjected to statistical analysis with the age and gender of patients, tumour localization, tumour growth and size, TNM stage, adenocarcinoma type, fibrosis, necrosis, metastasis and tumour invasion (by the Spearman’s correlation coefficient test). Results: The presence of neutrophils in the invasive front of tumour mass was associated with fibrosis and inflammatory cell infiltration in the invasive front of tumour. Macrophages in the invasive front of tumour were found to correlate with tumour growth (expanding and infiltrate). Macrophages and eosinophils were associated with inflammatory cell infiltration in the invasive front and in the centre of tumour. Conclusions: The type of inflammatory cells in the invasive front or centre of the tumour may be useful to prognoses clinical features of colorectal cancer
    Źródło:
    Progress in Health Sciences; 2020, 10(1); 69-76
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Shock dynamics induced by double-spot laser irradiation of layered targets
    Autorzy:
    Aliverdiev, A. A.
    Batani, D.
    Amirova, A. A.
    Benocci, R.
    Dezulian, R.
    Krouský, E.
    Pfeifer, M.
    Skala, J.
    Dudzak, R.
    Jakubowska, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/971507.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    laser shock
    high pressures
    non-uniformity smoothing
    Opis:
    We studied the interaction of a double-spot laser beam with targets using the Prague Asterix Laser System (PALS) iodine laser working at 0.44 μm wavelength and intensity of about 1015 W/cm2. Shock breakout signals were recorder using time-resolved self-emission from target rear side of irradiated targets. We compared the behavior of pure Al targets and of targets with a foam layer on the laser side. Results have been simulated using hydrodynamic numerical codes.
    Źródło:
    Nukleonika; 2015, 60, 2; 213-219
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The growth differentiation factor-15 (GDF-15) can be useful in the detection of distant metastases in sera of colorectal cancer patients
    Autorzy:
    Jakubowska, K.
    Pryczynicz, A.
    Dymicka-Piekarska, V.
    Cepowicz, D.
    Jagodzińska, D.
    Lewczuk, Ł.
    Lebelt, A.
    Ozimkiewicz, M.
    Kiszło, P.
    Guzińska-Ustymowicz, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/1917712.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Colorectal cancer
    Growth differentiation factor-15
    macrophage inhibitory cytokine-1
    serum.
    Opis:
    Purpose: Growth differentiation factor-15 (GDF- 15) protein belongs to a transforming growth factor-β family which determines the growth and differentiation of cells. In cancers, GDF-15 influences on the proliferation, differentiation, viability, migration and invasiveness of cancer cells. The aim of our study was to evaluate the expression of GDF-15 in the tissue and its levels in sera of patients with colorectal cancer. Materials and methods: The level of GDF-15 in the sera of 55 patients diagnosed with colorectal cancer was determined using the ELISA method whereas expression of this protein was performed by immunohistochemical method. Results: The mean value of GDF-15 levels in the sera of patients with colorectal cancer was significantly higher than in healthy control group (p<0.001). The expression of GDF-15 in the tissue was weak, moderate and strong in 23.6%, 15.7% and 60.7% cases, respectively. Statistical analysis showed that the expression of GDF-15 correlated with patients’ age (p<0.005) and non-mucinous type of cancer (p<0.001). The high GDF-15 levels in the serum was associated with tumor size (p<0.01) and distant metastases (p<0.05). Conclusions: According to our results, we postulate that the level of GDF-15 in serum can be use to assess the metastatic behavior of colorectal cancer
    Źródło:
    Progress in Health Sciences; 2016, 6(1); 40-48
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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