- Tytuł:
- Serosurvey of pathogenic hantaviruses among forestry workers in Hungary
- Autorzy:
-
Oldal, Miklós
Németh, Viktória
Madai, Mónika
Pintér, Réka
Kemenesi, Gábor
Dallos, Bianka
Kutas, Anna
Sebők, Judit
Horváth, Győző
Bányai, Krisztián
Jakab, Ferenc - Powiązania:
- https://bibliotekanauki.pl/articles/2178889.pdf
- Data publikacji:
- 2014-10-01
- Wydawca:
- Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
- Tematy:
-
hantavirus
forestry
serosurvey
Western blot
Hungary - Opis:
- Objectives: The aim of the study was to survey the prevalence of human hantavirus infections among forestry workers, who are considered a risk population for contracting the disease. Sera collected from volunteers were tested for antibodies against Dobrava-Belgrade (DOBV) and Puumala (PUUV) viruses. Material and Methods: For serological analyses, full capsid proteins of DOBV and PUUV viruses were produced in a bacterial expression system, while Ni-resin was used for protein purification. Samples were screened for anti-hantavirus antibodies by ELISA, results were confirmed by Western blot analysis. Results: A total of 835 samples collected from 750 males and 85 females were tested by indirect ELISA and positive test results were confirmed by Western blot assay. Out of the 45 ELISA-reactive samples, 38 were confirmed by Western blot analysis. The regional distribution of seropositive individuals was as follows: 1.9% (2/107) in the Danube-Tisza Plateau (Great Plains), 3.1% (10/321) in the Southern Transdanubian region, 5.2% (13/248) in the Northern Transdanubian, and 8.2% (13/159) in the North Hungarian Mountains. Conclusions: Our data show marked geographic differences in seroprevalence of pathogenic hantaviruses within Hungary, indicating elevated exposure to hantavirus infections in some areas.
- Źródło:
-
International Journal of Occupational Medicine and Environmental Health; 2014, 27, 5; 766-773
1232-1087
1896-494X - Pojawia się w:
- International Journal of Occupational Medicine and Environmental Health
- Dostawca treści:
- Biblioteka Nauki
Artykuł