- Tytuł:
- The influence of chromone based hydrazones on lipid peroxidation and bFGF concentration in the HL-60 cell line
- Autorzy:
-
Łazarenkow, Andrzej
Michalska, Marta
Gorąca, Anna
Mirowski, Marek
Nawrot-Modranka, Jolanta
Piechota-Polanczyk, Aleksandra - Powiązania:
- https://bibliotekanauki.pl/articles/1039590.pdf
- Data publikacji:
- 2013
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
hydrazone
chromone
phosphorohydrazone
HL-60
lipid peroxidation
bFGF - Opis:
- Natural and synthetic derivatives of benzo-γ-pyrones (i.e. flavones, chromones, and coumarins) and their synthetic analogues possess a wide range of biological properties in vitro and in vivo. In this paper we investigated the influence of two hydrazone compounds of chromones, 3-{[(2-dimethoxytiophosphoryl)-2-methylhydrazono]-methyl}-chromen-4-one (CH-3) and 2-amino-6-chloro-3-[(2-hydroxyethyl)-hydrazonomethyl]-chromen-4-one (A-12), on lipid peroxidation and bFGF concentration in the HL-60 cells. Both of the studied compounds had a significant influence on bFGF and TBARS in ranges -137.20 ~ 380.26% and -81.66 ~ -28.68%, respectively, in comparison with the control (counted as 0 %).
- Źródło:
-
Acta Biochimica Polonica; 2013, 60, 2; 259-262
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł