- Tytuł:
- Triterpenoid α-amyrin stimulates proliferation of human keratinocytes but does not protect them against UVB damage
- Autorzy:
-
Biskup, Edyta
Gołębiowski, Marek
Gniadecki, Robert
Stepnowski, Piotr
Łojkowska, Ewa - Powiązania:
- https://bibliotekanauki.pl/articles/1039744.pdf
- Data publikacji:
- 2012
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
UVB
BrdU incorporation
Rhaponticum carthamoides
α-amyrin
antioxidant activity - Opis:
- Rhaponticum carthamoides plants ("maral root") are widely used in Siberian folk medicine. The present study reports for the first time the presence of pentacyclic terpenoid, α-amyrin, in methanol extract from leaves of this plant. α-Amyrin induced proliferation of human keratinocytes (HaCaT) by about 18% while other extract components were ineffective. A panel of biochemical and cell-based assays testing the antioxidative and cytoprotective activites of α-amyrin indicated no antioxidative activity of this compound. α-Amyrin did not protect HaCaT cells against the damage caused by UVB radiation.
- Źródło:
-
Acta Biochimica Polonica; 2012, 59, 2; 255-260
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł