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Tytuł:
Comparison of the utility of the classic model (the Henderson-Hasselbach equation) and the Steward model (Strong Ion Approach) for the diagnostics of acid-base balance disorders in dogs with right sided heart failure
Autorzy:
Slawuta, P.
Glinska-Suchocka, K.
Powiązania:
https://bibliotekanauki.pl/articles/32238.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
utility
classic model
Henderson-Hasselbach equation
Steward model
diagnostics
acid-base balance
disorder
dog
right-sided heart failure
animal disease
Opis:
Classically, the acid-base balance (ABB) is described by the Henderson-Hasselbach equation, where the blood pH is a result of a metabolic components – the HCO₃⁻ concentration and a respiratory component – pCO₂. The Stewart model assumes that the proper understanding of the organisms ABB is based on an analysis of: pCO₂, Strong Ion difference (SID) – the difference strong cation and anion concentrations in the blood serum, and the Acid total (Atot) – the total concentration of nonvolatile weak acids. Right sided heart failure in dogs causes serious haemodynamic disorders in the form of peripheral stasis leading to formation of transudates in body cavities, which in turn causes ABB respiratory and metabolic disorders. The study was aimed at analysing the ABB parameters with the use of the classic method and the Stewart model in dogs with the right sided heart failure and a comparison of both methods for the purpose of their diagnostic and therapeutic utility. The study was conducted on 10 dogs with diagnosed right sided heart failure. Arterial and venous blood was drawn from the animals. Analysis of pH, pCO₂ and HCO₃⁻ was performed from samples of arterial blood. Concentrations of Na+, K+, Cl-, Pinorganic, albumins and lactate were determined from venous blood samples and values of Strong Ion difference of Na+, K+ and Cl- (SID₃), Strong Ion difference of Na+, K+, Cl- and lactate (SID4), Atot, Strong Ion difference effective (SIDe) and Strong Ion Gap (SIG₄) were calculated. The conclusions are as follows: 1) diagnosis of ABB disorders on the basis of the Stewart model showed metabolic alkalosis in all dogs examined, 2) in cases of circulatory system diseases, methodology based on the Stewart model should be applied for ABB disorder diagnosis, 3) if a diagnosis of ABB disorders is necessary, determination of pH, pCO₂ and HCO₃⁻ as well as concentrations of albumins and Pinorganic should be determined on a routine basis, 4) for ABB disorder diagnosis, the classic model should be used only when the concentrations of albumins and Pinorganic are normal.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An attempt to use the peritoneal cavity fluid in the diagnostics of acid-base balance disorders in dogs
Autorzy:
Slawuta, P.
Glinska-Suchocka, K.
Powiązania:
https://bibliotekanauki.pl/articles/30556.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The acid-base balance parameters (ABB) of blood are used in the diagnostics and therapy of acidosis or alkalosis type disorders. Nowadays, some reports on the attempts to use the body cavity fluid for the diagnostics of the ABB disorders have appeared in the human medicine. The study has aimed at comparing the acid-base balance parameters (ABB): pH, pCO₂, and HCO₃⁻ determined in the arterial blood and the fluid from the peritoneal cavity in dogs. The study was carried out on 20 dogs suffering from ascites developed as a result of the chronic renal failure. 1 ml of full blood was drawn from each dog from its femoral artery to a heparinized syringe equipped with a needle with an internal diameter of 0.7 mm and the puncture of the abdominal cavity was carried out in the white line. In the sample of arterial blood and the sample of the abdominal cavity fluid drawn the ABB parameters were determined. In the group examined, the ABB parameters determined for the arterial blood and the fluid had comparable numeric values and the same nature of the ABB disorder diagnosed on the basis of them. The conclusions are as follows: the results of the effusion fluid gasometry depend on the mechanism of the fluid formation and, in the case when it comes from the developed capillary network, a pressure of gases and remaining ABB parameters are similar to those determined for the arterial blood.
Źródło:
Polish Journal of Veterinary Sciences; 2013, 16, 3
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The use of elements of the Stewart model (Strong Ion Approach) for the diagnostics of respiratory acidosis on the basis of the calculation of a value of a modified anion gap (AGm) in brachycephalic dogs
Autorzy:
Slawuta, P.
Glinska-Suchocka, K.
Cekiera, A.
Powiązania:
https://bibliotekanauki.pl/articles/2087993.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Apart from the HH equation, the acid-base balance of an organism is also described by the Stewart model, which assumes that the proper insight into the ABB of the organism is given by an analysis of: pCO2, the difference of concentrations of strong cations and anions in the blood serum - SID, and the total concentration of nonvolatile weak acids - Acid total. The notion of an anion gap (AG), or the apparent lack of ions, is closely related to the acid-base balance described according to the HH equation. Its value mainly consists of negatively charged proteins, phosphates, and sulphates in blood. In the human medicine, a modified anion gap is used, which, including the concentration of the protein buffer of blood, is, in fact, the combination of the apparent lack of ions derived from the classic model and the Stewart model. In brachycephalic dogs, respiratory acidosis often occurs, which is caused by an overgrowth of the soft palate, making it impossible for a free air flow and causing an increase in pCO2 - carbonic acid anhydride The aim of the present paper was an attempt to answer the question whether, in the case of systemic respiratory acidosis, changes in the concentration of buffering ions can also be seen. The study was carried out on 60 adult dogs of boxer breed in which, on the basis of the results of endoscopic examination, a strong overgrowth of the soft palate requiring a surgical correction was found. For each dog, the value of the anion gap before and after the palate correction procedure was calculated according to the following equation: AG = ([Na+ mmol/l] + [K+ mmol/l]) - ([Cl-mmol/l] + [HCO3-mmol/l]) as well as the value of the modified AG - according to the following equation: AGm = calculated AG + 2.5 x (albuminsr - albuminsd). The values of AG calculated for the dogs before and after the procedure fell within the limits of the reference values and did not differ significantly whereas the values of AGm calculated for the dogs before and after the procedure differed from each other significantly. Conclusions: 1) On the basis of the values of AGm obtained it should be stated that in spite of finding respiratory acidosis in the examined dogs, changes in ion concentration can also be seen, which, according to the Stewart theory, compensate metabolic ABB disorders 2) In spite of the fact that all the values used for calculation of AGm were within the limits of reference values, the values of AGm in dogs before and after the soft palate correction procedure differed from each other significantly, which proves high sensitivity and usefulness of the AGm calculation as a diagnostic method.
Źródło:
Polish Journal of Veterinary Sciences; 2015, 18, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Serum concentrations of PIIINP aminopeptide in dogs with liver fibrosis
Autorzy:
Glinska-Suchocka, K.
Orlowska, A.
Jankowski, M.
Kubiak, K.
Spuzak, J.
Powiązania:
https://bibliotekanauki.pl/articles/30439.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of the study was to evaluate the serum concentration of the type III procollagen aminopeptide in dogs, and to assess its utility in the diagnosis of liver fibrosis. The study was carried out on 20 dogs of different breeds and of both genders, between 7 and 15 years old. Based on the results of the histopathological examination and the evaluation of the degree of liver fibrosis, the dogs were divided into five groups. The mean serum PIIINP concentration in the group of dogs with stage 1 and 2 liver fibrosis (groups 2 and 3) was five-fold higher than in healthy dogs (group 1). In turn, the mean PIIINP concentration in the group of dogs with stage 3 (group 4) and stage 4 (group 5) fibrosis was 10-fold higher than that of the control group (group 1). Based on the results, we found that the serum PIIINP concentration correlated with the degree of liver fibrosis, assessed based on a histopathological examination. Therefore, PIIINP serum concentration tests may be a promising non-invasive diagnostic technique that could be used in veterinary hepatology to assess the degree of liver fibrosis.
Źródło:
Polish Journal of Veterinary Sciences; 2016, 19, 2
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Suitability of using serum hialuronic acid concentrations in the diagnosis of canine liver fibrosis
Autorzy:
Glinska-Suchocka, K.
Orlowska, A.
Spuzak, J.
Jankowski, M.
Kubiak, K.
Powiązania:
https://bibliotekanauki.pl/articles/31758.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
There are multiple dynamic changes associated with the metabolism of the extracellular matrix (ECM) which occur in the course of liver fibrosis. Therefore, the evaluation of parameters reflecting the deposition of ECM, the activity of myofibroblasts and the synthesis and degradation of collagen may aid in the diagnosis of liver fibrosis. Hyaluronic acid is considered to be a marker of ECM deposition. It is a glycosaminoglycan synthesized by hepatic stellate cells and degraded by hepatic sinusoidal endothelial cells. The aim of this study was to evaluate the concentration of hyaluronic acid in dogs with different degrees of liver fibrosis. The study was carried out on 29 dogs with liver disease. A core needle biopsy of the liver was performed in order to assess the degree of hepatic inflammation. Then, hyaluronic acid serum concentrations were measured. The dogs were divided into five groups based on the histopathological examination and the evaluation of the degree of hepatic fibrosis. The study showed that serum hyaluronic acid concentrations were low in patients with first stage liver fibrosis and in controls, while they were twice as high as control values in the group of dogs with second stage liver fibrosis. These concentrations were three-fold greater than control values in patients with third stage liver fibrosis, and seven-fold greater in patients with liver cirrhosis. Based on the results, it was concluded that serum hyaluronic acid is a useful marker of liver fibrosis and may aid in determining the degree of its advancement.
Źródło:
Polish Journal of Veterinary Sciences; 2015, 18, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Accuracy of real-time shear wave elastography in the assessment of normal liver tissue in the guinea pig (cavia porcellus)
Autorzy:
Glinska-Suchocka, K.
Kubiak, K.
Spuzak, J.
Jankowski, M.
Borusewicz, P.
Powiązania:
https://bibliotekanauki.pl/articles/32020.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Shear wave elastography is a novel technique enabling real-time measurement of the elasticity of liver tissue. The color map is superimposed on the classic ultrasound image of the assessed tissue, which enables a precise evaluation of the stiffness of the liver tissue. The aim of the study was to assess the stiffness of normal liver tissue in the guinea pig using shear wave elastography. The study was carried out on 36 guinea pigs using the SuperSonic Imagine Aixplorer scanner, and a 1 to 6 MH convex SC6-1 transducer. An ultrasound guided Try-Cut liver core needle biopsy was carried out in all the studied animals and the collected samples were examined to exclude pathological lesions. The mean liver tissue stiffness ranged from 0.89 to 5.40 kPa. We found that shear wave elastography is an easy, non-invasive technique that can be used to assess the stiffness of liver tissue. The obtained results can be used in future studies to assess the types and changes of liver tissue in the course of various types of liver disease.
Źródło:
Polish Journal of Veterinary Sciences; 2017, 20, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
7S fragment of type iv collagen as a serum marker of canine liver fibrosis
Autorzy:
Glinska-Suchocka, K.
Orlowska, A.
Kubiak, K.
Spuzak, J.
Jankowski, M.
Powiązania:
https://bibliotekanauki.pl/articles/32417.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of this study was to assess whether the serum levels of the 7S fragment of type IV collagen may aid in diagnosing liver fibrosis in dogs. The study was carried out on 20 dogs with liver disease. Serum levels of the 7S fragment of type IV collagen were measured in all dogs. The analysis showed that healthy dogs and dogs with type 1, 2 and 3 liver fibrosis had low serum concentrations of the 7S fragment of type IV collagen compared to dogs with type 4 liver fibrosis. The study revealed that the assessment of serum levels of the 7S fragment of type IV collagen is useful in the diagnosis of advanced liver fibrosis and cirrhosis.
Źródło:
Polish Journal of Veterinary Sciences; 2016, 19, 3
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Detection of Helicobacter spp. in the saliva of dogs with gastritis
Autorzy:
Jankowski, M.
Spuzak, J.
Kubiak, K.
Glinska-Suchocka, K.
Biernat, M.
Powiązania:
https://bibliotekanauki.pl/articles/32000.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of this study was to identify the species and determine the prevalence of gastric Helicobacter in the saliva of dogs with gastritis. The study was carried out on 30 dogs of different breeds, genders and ages, which were diagnosed with gastritis. The nested-PCR method was used to detect Helicobacter spp. in saliva. Helicobacter bacteria were found in the saliva samples of 23 (76.6%) dogs. Helicobacter heilmannii was the most commonly detected species of gastric Helicobacter spp. in canine saliva, and was found in 22 (73.3%) cases. The results indicate that gastric Helicobacter spp. occurs relatively frequently in dogs with gastritis. Moreover, the saliva of dogs with gastritis may be a source of Helicobacter spp. infection for humans and other animals. However, further studies are needed to confirm this finding as the PCR method does not distinguish active from inactive infections.
Źródło:
Polish Journal of Veterinary Sciences; 2016, 19, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Detection of gastric Helicobacter spp. in stool samples of dogs with gastritis
Autorzy:
Jankowski, M.
Spuzak, J.
Kubiak, K.
Glinska-Suchocka, K.
Biernat, M.
Powiązania:
https://bibliotekanauki.pl/articles/30957.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of this study was to determine the prevalence and identify the species of gastric Helicobacter in the stool of dogs with gastritis. The study was carried out on thirty dogs of different breeds, of both genders and of various ages, diagnosed with gastritis. Helicobacter spp. was detected in stool samples using the nested-PCR method. Helicobacter bacteria were identified in stool samples from seven (23.3%) dogs. Helicobacter heilmannii was found to be the most common species of gastric Helicobacter. Helicobacter salomonis was identified much less frequently, while Helicobacter felis, Helicobacter pylori and Helicobacter bizzozeronii were not detected in any of the samples.
Źródło:
Polish Journal of Veterinary Sciences; 2016, 19, 2
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sonoelastography in differentiation of benign and malignant testicular lesion in dogs
Autorzy:
Glinska-Suchocka, K.
Jankowski, M.
Kubiak, K.
Spuzak, J.
Dzimira, S.
Powiązania:
https://bibliotekanauki.pl/articles/31014.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Present study aimed to evaluae the elasticity of tumorous testicular lesions and usefulness of the elastographic examination for diagnosing lesions in the testes. The study was carried out on nine dogs in which tumorous testicular lesions had been found in the ultrasonographic examination. In all the animals examined, the elastographic examination of the lesions was performed and then castration and the histopathological examination of specimens in order to determine the type of the changes. On the basis of the results of the histopathological examination the dogs were divided into two groups: group I - consisted of three dogs in which nonneoplastic testicular lesions were found and group II comprised six dogs in which neoplasic lesions that began in testicular interstitial cells (Leydigoma) were detected. The lesions observed in dogs of group I showed low stiffness (average 11.25 kPa, range 6.1 to 16.4 kPa), whereas the lesions found in dogs of group II were characterized by high stiffness (average 91.85 kPa, range 52.3 to 131.4 kPa). On the basis of a scale proposed by Goodie et al. (2012), the lesions in group I were in the range of SC1,and in turn, the lesions in group II were in the range of SC 3 inverted. Based on the results obtained, it can be stated that the sonoelastographic examination is useful method for the screening diagnostics of testicular lesions.
Źródło:
Polish Journal of Veterinary Sciences; 2014, 17, 3
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of shear wave elastography in the diagnosis of mammary gland neoplasm in dogs
Autorzy:
Glinska-Suchocka, K.
Jankowski, M.
Kubiak, K.
Spuzak, J.
Dzimira, S.
Nicpon, J.
Powiązania:
https://bibliotekanauki.pl/articles/31842.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of the study was to evaluate the usefulness of elastography in the differential diagnosis of benign and malignant tumours of the mammary gland in dogs. The study was performed to 12 female dogs of different breeds aged 5-12 years in which tumoral lesions of the mammary gland were found in the clinical examination. In all the animals elastographic examination of the lesions was carried out and then the fine-needle aspiration biopsy was performed to determine the nature and degree of malignancy of the lesions. The examinations proved that benign neoplasms of the mammary gland showed low stiffness (average 22.42 kPa, range 19 to 42.4 kPa), whereas malignant neoplasms were characterized by high stiffness (average 235.44 kPa, range 171 to 300 kPa). On the basis of the results obtained we conclude that the elastography of proliferative lesions of the mammary gland is a useful diagnostic method for distinguishing benign neoplastic lesions from malignant neoplasms.
Źródło:
Polish Journal of Veterinary Sciences; 2013, 16, 3
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An analysis of pH, pO2 and pCO2 in the peritoneal fluid of dogs with ascites of various etiologies
Autorzy:
Glinska-Suchocka, K.
Slawuta, P.
Jankowski, M.
Kubiak, K.
Spuzak, J.
Borusewicz, P.
Powiązania:
https://bibliotekanauki.pl/articles/32394.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of the study was to assess pH, pO2 and pCO2 in peritoneal fluid. The study was conducted on a group of 22 dogs with symptoms of ascites. Group 1 consisted of 4 dogs with adenocarcinoma, group 2 – of 6 dogs with glomerulonephritis, group 3 of 8 dogs with hepatic cirrhosis and group 4 of 4 dogs with bacterial peritonitis. An abdominal cavity puncture was performed in all dogs and the fluid was drawn into a heparinized syringe in order to assess pH, pO2 and pCO2. The analysis of pH in the peritoneal fluid revealed statistically significant differences between group 4 and groups 1 (p=0.01), 2 (p=0.01), and 3 (p=0.01). The lowest pH value compared to the other studied groups was recorded in group 4. In group 4, the pO2 was the lowest compared to the other groups (group 1 p=0.01, group 2 p=0.01, group 3 p=0.01). The value of pCO2 was the highest in group 4 compared to groups 1, 2, and 3. The study found statistically significant differences in pH, pO2 and pCO2 between group 4 (the group of dogs with bacterial peritonitis) and the other groups of dogs. This was probably linked to the pathogenesis of peritonitis. As a result of an inflammatory reaction within the peritoneal cavity, there is an increase in fibrin accumulations leading to a decreased oxygen supply causing the oxidative glucose metabolism to change into a non-oxidative glucose metabolism. This, in turn, causes a decrease in pH, acidosis, and a low oxidoreduction potential. It also impairs phagocytosis and activates proteolytic enzymes which create ideal conditions for the growth of anaerobic bacteria. The obtained results indicate that the pH, pO2 and pCO2 may be used to differentiate bacterial peritonitis from ascites of other etiologies.
Źródło:
Polish Journal of Veterinary Sciences; 2016, 19, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neoplastic lesions in the nasal cavities of dogs
Autorzy:
Spuzak, J.
Jankowski, M.
Kubiak, K.
Glinska-Suchocka, K.
Grzegory, M.
Halon, A.
Powiązania:
https://bibliotekanauki.pl/articles/2087949.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
This paper aims at evaluating the frequency of nasal cavity tumors in dogs as well as comparing an endoscopic examination with a histopathological evaluation of the collected biopsy specimens. The study was conducted on 68 dogs. During the endoscopic examination, proliferative lesions were recognized in 20 dogs. During the histopathological examination, neoplastic lesions were confirmed in 95% of the dogs in which proliferative lesions were identified in the endoscopic examination. Adenocarcinoma occurred most frequently in the population under study.
Źródło:
Polish Journal of Veterinary Sciences; 2014, 17, 2; 375-377
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Najczęstsze przyczyny zakażeń dróg moczowych u psów i kotów oraz ich leczenie
The most common causes of urinary tract infections and their treatment in dogs and cats
Autorzy:
Grzegory, M.
Kubiak, K.
Jankowski, M.
Spuzak, J.
Bakowska, J.
Glinska-Suchocka, K.
Dzimira, S.
Powiązania:
https://bibliotekanauki.pl/articles/860409.pdf
Data publikacji:
2014
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
zwierzeta towarzyszace
psy
koty
choroby drog moczowych
zapalenie drog moczowych
etiologia
objawy chorobowe
diagnostyka
leczenie
Źródło:
Życie Weterynaryjne; 2014, 89, 10
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rak płaskonabłonkowy jamy ustnej kotów - rozpoznawanie i leczenie
Feline oral squamous cell carcinoma - diagnosis and treatment
Autorzy:
Zawlocka-Hutny, E.
Jankowski, M.
Kubiak, K.
Glinska-Suchocka, K.
Spuzak, J.
Bakowska, J.
Borusewicz, P.
Powiązania:
https://bibliotekanauki.pl/articles/862170.pdf
Data publikacji:
2015
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
onkologia weterynaryjna
koty
nowotwory
rak plaskonablonkowy jamy ustnej
etiologia
objawy chorobowe
diagnostyka
badania radiologiczne
badania krwi
leczenie
rokowanie
Źródło:
Życie Weterynaryjne; 2015, 90, 01
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
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