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    Wyświetlanie 1-5 z 5
    Tytuł:
    Czy Candida auris jest nowym groźnym patogenem?
    Is Candida auris a new threatening fungal pathogen?
    Autorzy:
    Gliński, Zdzisław
    Żmuda, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/22181023.pdf
    Data publikacji:
    2021
    Wydawca:
    Krajowa Izba Lekarsko-Weterynaryjna
    Tematy:
    grzyby
    Candida auris
    epidemiologia
    grzybice
    objawy kliniczne
    rozpoznanie
    leczenie
    drogi zakażenia
    czynniki chorobotwórcze
    lekooporność
    źródła zakażenia
    antifungal therapy
    diagnostic techniques
    drugs resistance
    Opis:
    This article aims at presenting an emerging, yeast-related, health threat. Candida auris (Metschnikowiaceae, Candida/Clavispora clade), is an emerging fungus, that presents a serious global health threat. It causes wounds, ears, respiratory and urinary tracts infections. In some patients, these yeasts can enter the bloodstream and spread throughout the body, causing serious systemic infections. C.auris is often resistant to commonly used antifungal drugs, such as amphotericin B, polyenes or echinocandins, making infections difficult to treat. C. auris persists in the environment for months, and persistent environmental contamination, contaminated medical equipment and other fomites, are believed to play a role in nosocomial C. auris transmission. Specialized laboratory methods (RT-PCR, MALDI-TOF MS), are needed to accurately identify C. auris yeast. Echinocandins are currently recommended as first-line therapy in adults and in infants (children above 2 months of age). For neonates amphotericin B deoxycholate is recommended. It is suspected, that C. auris may also be pathogenic to animals.
    Źródło:
    Życie Weterynaryjne; 2021, 96, 10; 709-712
    0137-6810
    Pojawia się w:
    Życie Weterynaryjne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ospa małpia potencjalnym zagrożeniem
    Monkeypox – a potential zoonotic threat
    Autorzy:
    Gliński, Zdzisław
    Żmuda, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/22403346.pdf
    Data publikacji:
    2022
    Wydawca:
    Krajowa Izba Lekarsko-Weterynaryjna
    Tematy:
    ospa malpia
    epidemiologia
    charakterystyka
    patogeneza
    rozpoznanie
    człowiek
    zagrożenia zdrowia
    choroby odzwierzęce
    wirus ospy małpiej
    wrota zakażenia
    drogi zakażenia
    monkeypox
    smallpox
    pathology
    control
    Opis:
    Monkeypox is an emerging zoonotic disease and a potential biological weapon. It is caused by enveloped, complex, double-stranded DNA Orthopoxvirus (Poxviridae), closely related to smallpox virus. Since 1958 monkeypox has been reported in people in several central and western African countries, USA and Europe. Transmission of monkeypox virus (MPV), occurs when a person comes into close contact with skin lesions, body fluids, respiratory droplets from infected animal or human, or with contaminated fomites. Monkeypox is a communicable disease in nonhuman primates, wild rodents and prairie dogs. Clinical symptoms in prairie dogs and hon-human primates include cough, history of fever, conjunctivitis, lack of appetite, respiratory signs and rash. In humans, the disease begins with fever, headache, muscle aches, and exhaustion. The patient develops a rash progressing to macules, papules, vesicles, pustules and scabs, often resembling chickenpox. In monkeypox human cases lymphadenopathy is prominent distinguishing this disease from smallpox, already eradicated worldwide. In the African epidemics, 90% of the patients were children below 15 years of age. Monkeypox can be diagnosed with molecular methods (RT-PCR, pan-orthopox PCR), immunohistochemistry, isolation of MPV in cell culture, ELISA and or electron microscopy. To treat patients and to control monkeypox outbreak, the smallpox vaccine, antivirals drugs, and vaccinia immune globulin (VIG) can be used. Monkeypox is a disease of global public health importance and in this article major issues related to this emerging zoonosis are presented.
    Źródło:
    Życie Weterynaryjne; 2022, 97, 07; 433-437
    0137-6810
    Pojawia się w:
    Życie Weterynaryjne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pytioza
    Pythiosis
    Autorzy:
    Gliński, Zdzisław
    Żmuda, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/22180754.pdf
    Data publikacji:
    2021
    Wydawca:
    Krajowa Izba Lekarsko-Weterynaryjna
    Tematy:
    konie
    psy
    koty
    pytioza
    Pythium insidiosum
    objawy chorobowe
    diagnostyka
    profilaktyka
    leczenie
    choroby zwierząt
    drogi zakażenia
    pythiosis
    dog
    horse
    humans
    Opis:
    This review aims at the presentation of rare, sporadic infection in animals and humans, following contact with contaminated water. Pythiosis, caused by a water mould Pythium insidiosum, occurs primarily in dogs, horses and humans, but can also affect calves, sheep, cats, birds and even panthers and tigers. Susceptible hosts become infected after contact with motile zoospores, that invade the wounded skin when the animals wade in stagnant water containing this opportunistic organism. In dogs, pythiosis affects the gastrointestinal system and lymph nodes, and seldom the skin. The clinical symptoms include vomiting, weight loss, intermittent diarrhea and palpable masses in the abdomen. Expansion of the infection to the pancreas, mesenteric lymph nodes and bile ducts can occur. Extensive weight loss may be evident. Cutaneous pythiosis is the usual presentation in horses. Skin lesions are pyogranulomatous or fibrogranulomatous and tend to be progressive. In the horse the lesions are large (up to 45 cm), discharging swellings, usually on the extremities, ventral trunk or head. Yellow, necrotic masses termed “kunkers” or “leeches” can be removed intact from the granulomas. Nasal mucosa can be involved. The respiratory condition caused by inhalation of aerosolized Pythium spores is a Pythium-induced allergic syndrome. In humans, three forms of pythiosis are observed: granulomatous and ulcerative lesions involving the skin and subcutaneous tissues of the limbs and face, ophthalmic pythiosis causing keratitis, and systemic pythiosis with vascular involvement leading to vasculitis, thrombosis and aneurysms.
    Źródło:
    Życie Weterynaryjne; 2021, 96, 01; 23-27
    0137-6810
    Pojawia się w:
    Życie Weterynaryjne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Czy wirus Lassa będzie najgroźniejszym zoonotycznym patogenem?
    Will Lassa virus become the most fearsome zoonotic pathogen?
    Autorzy:
    Gliński, Zdzisław
    Żmuda, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/22339828.pdf
    Data publikacji:
    2022
    Wydawca:
    Krajowa Izba Lekarsko-Weterynaryjna
    Tematy:
    objawy chorobowe
    patogeneza
    wirus Lassa
    epidemiologia
    zmiany anatomopatologiczne
    zmiany histopatologiczne
    rozpoznanie
    leczenie
    profilaktyka
    znaczenie zoonotyczne
    gorączka Lassa
    czynniki chorobotwórcze
    źródła zakażenia
    drogi zakażenia
    symptoms
    pathogenesis
    control
    Lassa fever
    Opis:
    Lassa virus (Arenaviridae), is the etiological agent of Lassa fever, a severe human disease with high mortality rates for hospitalized patients. Lassa fever can be difficult to distinguish clinically from other viral hemorrhagic fevers. The virus is initially spread to people via contact with urine or feces of an infected multimammate mouse and rat, that remain carriers for life. Once infected, people may transmit Lassa virus in both community and health care settings, by contaminated medical equipment and direct contact with bodily secretions. About 15–20% of hospitalized people with Lassa fever will die from the illness. However, many infected people do not develop symptoms, which typically include fever, headache, vomiting and muscles pain. The main feature of fatal illness is impaired or severely delayed cell mediated immunity leading to fulminant viremia. Early recognition and initiation of targeted care increase patients surviving rates. Lassa fever is diagnosed by ELISA, which may detect IgM and IgG antibodies as well as Lassa virus antigen and RT-PCR used in the early stage of disease. There is currently no licensed vaccine against Lassa fever, and the only treatment available is based on ribavirin. In this article epidemiological aspects as well as diagnostics approaches are presented and discussed in the context of possibly increasing the public health threat with Lassa fever in European countries.
    Źródło:
    Życie Weterynaryjne; 2022, 97, 04; 245-249
    0137-6810
    Pojawia się w:
    Życie Weterynaryjne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Choroba maedi-visna nadal problemem w hodowli owiec
    Maedi-visna disease, continuous problem in sheep farming
    Autorzy:
    Gliński, Zdzisław
    Żmuda, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/22443120.pdf
    Data publikacji:
    2022
    Wydawca:
    Krajowa Izba Lekarsko-Weterynaryjna
    Tematy:
    owce
    choroba maedi-visna
    epidemiologia
    etiologia
    wirus maedi-visna
    patogeneza
    czynniki ryzyka
    objawy kliniczne
    zmiany anatomopatologiczne
    zmiany histopatologiczne
    diagnostyka
    choroby zwierząt
    źródła zakażenia
    drogi zakażenia
    zwalczanie chorób zwierząt
    kontrola chorób
    maedi-visna
    control
    serology
    sheep
    epidemiology
    Opis:
    Maedi-visna is a multi-systemic disease of sheep caused by a non-oncogenic, exogenous retrovirus of the Lentiviridae subfamily. It is mainly transmitted through the ingestion of milk from infected sheep, although disease can be spread within flocks through direct contact and transmission can occur also in utero. Maedi usually begins insidiously and leads to a classical interstitial pneumonia. On postmortem examination, the lungs may be 2-4 times heavier than normal, due to decreased elasticity and fibrosis. Regional lymph nodes are enlarged with formation of lymphoid follicles with active germinal centers. Visna - the neurological form of the disease, is characterized by chronic and active meningoencephalomyelitis and chorioiditis with massive infiltrations of mononuclear cells around the blood vessels, microglial nodules formation and astrogliosis. Virus isolation is very specific but of variable sensitivity. The cytopathic effects are characteristic, consisting of the appearance of stellate cells and syncytia. The diagnostic methods currently used are based on the detection of either antibodies or the viral genome. The three most commonly tests used, are the PCR and RT-PCR, agar gel immunodiffusion test (AGID) and the enzyme-linked immunosorbent assay (ELISA). Western blot analysis and radio-immunoprecipitation are also performed, but only in specialized laboratories. No commercial vaccines are available to control infection, and to date, monitoring programs have proved to be the only effective tool in controlling this disease.
    Źródło:
    Życie Weterynaryjne; 2022, 97, 09; 587-591
    0137-6810
    Pojawia się w:
    Życie Weterynaryjne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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