Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę "Enhancement" wg kryterium: Temat


Wyświetlanie 1-3 z 3
Tytuł:
Dose enhancement in brachytherapy in the presence of gold nanoparticles : a Monte Carlo study on the size of gold nanoparticles and method of modelling
Autorzy:
Ghorbani, M.
Pakravan, D.
Bakhshabadi, M.
Meigooni, A. S.
Powiązania:
https://bibliotekanauki.pl/articles/146605.pdf
Data publikacji:
2012
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
brachytherapy
dose enhancement
gold nanoparticles
Monte Carlo (MC)
Opis:
The aim of this study was to evaluate the effect of the size of gold nanoparticles (GNPs) on dose enhancement in brachytherapy with photon emitting sources. Four photon emitting sources, 125I, 169Yb, 103Pd, and 192Ir were simulated and dose rate constant and radial dose functions were compared with published corresponding data for these sources. Dose enhancement factor in the presence of gold nanoparticles of 30 mg/ml concentration was calculated separately for nanoparticles with a diameter of 50, 100 and 200 nm. Gold nanoparticles were simulated precisely as nanospheres utilizing a lattice option in the MCNPX Monte Carlo code and the results were compared with those obtained with a simple model in which gold atoms are distributed uniformly in tumor volume as a simple mixture. Among the four mentioned sources, the dose enhancement related to 125I source is higher. Our results have shown that with gold nanoparticles of higher diameter, the level of dose enhancement is higher in the tested tumor. It has been also observed that the simple model overestimates the dose enhancement factor when compared with the precise model in which nanoparticles are defined according to the Monte Carlo code. In the energy range produced by the brachytherapy sources, the dose enhancement is higher when using brachytherapy sources with lower energy. Among the size range of gold nanoparticles used in medicine, it is predicted that nanoparticles with higher diameter can be more useful when are utilized in brachytherapy. It is also recommended that when calculating dose enhancements, a precise model be used for modelling of nanoparticles in the Monte Carlo simulations.
Źródło:
Nukleonika; 2012, 57, 3; 401-406
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A Monte Carlo study on dose enhancement and photon contamination production by various nanoparticles in electron mode of a medical linac
Autorzy:
Bahreyni Toossi, M. T.
Ghorbani, M.
Sobhkhiz Sabet, L.
Akbari, F.
Mehrpouyan, M.
Powiązania:
https://bibliotekanauki.pl/articles/146518.pdf
Data publikacji:
2015
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
dose enhancement
electron mode
Monte Carlo
nanoparticles
photon contamination
Opis:
The aim of this study is the evaluation of electron dose enhancement and photon contamination production by various nanoparticles in the electron mode of a medical linac. MCNPX Monte Carlo code was used for simulation of Siemens Primus linac as well as a phantom and a tumor loaded with nanoparticles. Electron dose enhancement by Au, Ag, I and Fe2O3 nanoparticles of 7, 18 and 30 mg/ml concentrations for 8, 12 and 14 MeV electrons was calculated. The increase in photon contamination due to the presence of the nanoparticles was evaluated as well. The above effects were evaluated for 500 keV and 10 keV energy cut-offs defined for electrons and photons. For 500 keV energy cut-off, there was no significant electron dose enhancement. However, for 10 keV energy cut-off, a maximum electron dose enhancement factor of 1.08 was observed for 30 mg/ml of gold nanoparticles with 8 MeV electrons. An increase in photon contamination due to nanoparticles was also observed which existed mainly inside the tumor. A maximum photon dose increase factor of 1.07 was observed inside the tumor with Au nanoparticles. Nanoparticles can be used for the enhancement of electron dose in the electron mode of a linac. Lower energy electron beams, and nanoparticles with higher atomic number, can be of greater benefi t in this field. Photons originating from nanoparticles will increase the photon dose inside the tumor, and will be an additional advantage of the use of nanoparticles in radiotherapy with electron beams.
Źródło:
Nukleonika; 2015, 60, No. 3, part 1; 489-496
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Tumor dose enhancement by gold nanoparticles in a 6 MV photon beam: a Monte Carlo study on the size effect of nanoparticles
Autorzy:
Pakravan, D.
Ghorbani, M.
Momennezhad, M.
Powiązania:
https://bibliotekanauki.pl/articles/146977.pdf
Data publikacji:
2013
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
Monte Carlo (MC) simulation
medical linac
dose enhancement
gold nanoparticle (GNP)
flattening filter free (FFF)
Opis:
In this study after benchmarking of Monte Carlo (MC) simulation of a 6 MV linac, the simulation model was used for estimation of tumor dose enhancement by gold nanoparticles (GNPs). The 6 MV photon mode of a Siemens Primus linac was simulated and a percent depth dose and dose profiles values obtained from the simulations were compared with the corresponding measured values. Dose enhancement for various sizes and concentrations of GNPs were studied for two cases with and without the presence of a flattening filter in the beam’s path. Tumor dose enhancement with and without the presence of the flattening filter was, respectively 1–5 and 3–10%. The maximum dose enhancement was observed when 200 nm GNPs was used and the concentration was 36 mg/g tumor. Furthermore, larger GNPs resulted in higher dose values in the tumor. After careful observation of the dose enhancement factor data, it was found that there is a poor relation between the nanoparticle size and dose enhancement. It seems that for high energy photons, the dose enhancement is more affected by the concentration of nanoparticles than their size.
Źródło:
Nukleonika; 2013, 58, 2; 275-280
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

    Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies