Autor: Kolesińska, B. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Cellulose as a matrix for synthesis of the library of molecular receptors useful for screening of antihistamine compounds
Autorzy:: Walczak, M. E.
Fraczyk, J.
Kaminski, Z. J.
Kolesinska, B.
Powiązania:: https://bibliotekanauki.pl/articles/285804.pdf
Data publikacji:: 2017
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: biopolymers
antihistamine compounds
molecular receptors
Źródło:: Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 50
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Detonation nanodiamond particles modified by non-steroidal anti-inflammatory drugs in vitro examination
Autorzy:: Mitura, K.
Wilczek, P.
Niemiec-Cyganek, A.
Morenc, M.
Dudek, M.
Sobczyk-Guzenda, A.
Fraczyk, J.
Kolesińska, B.
Powiązania:: https://bibliotekanauki.pl/articles/284974.pdf
Data publikacji:: 2017
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: detonation nanodiamond particles
chemical modification
anti-inflammatory drugs
FTIR spectroscopy
mouse fibroblasts
Opis:: Most recently it has been found that nanodiamond particles have very interesting properties. There are number of research communications that detonation nanodiamond particles (NDPs) are fairly reactive and their surface can be effectively modified by chemical methods. The hydroxyl-modified NDPs were obtained by Fenton reaction, amine-functionalized NDPs were obtained by chemical reduction of the nitro- -functionalized surface and carboxyl-modified NDPs by oxidation by using H2O2 under acidic conditions. NDPs functionalized by hydroxyl- and amine- groups and amino groups were used for covalent binding of non-steroidal anti-inflammatory pharmaceuticals (aspirin, ketoprofen, ibuprofen, naproxen) via ester or amide bonds. These results of the studies proved the activity of the conjugates of active substance-NDP and study the rate of release of active substance from the NDPs surface by in vitro examinations with mouse fibroblasts. The progress of the reaction and the characteristics of the products were determined by using FT-IR. Chemical and physical structures of materials were also investigated by Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS). DRIFT spectra show the modification of nanodiamond by ketoprofen, naproxen, ibuprofen and aspirin.
Źródło:: Engineering of Biomaterials; 2017, 20, 140; 12-20
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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