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Wyświetlanie 1-2 z 2
Tytuł:
Comparison of antioxidant activity of extracts of hop leaves harvested in different years
Autorzy:
Muzykiewicz, Anna
Nowak, Anna
Zielonka-Brzezicka, Joanna
Florkowska, Katarzyna
Duchnik, Wiktoria
Klimowicz, Adam
Powiązania:
https://bibliotekanauki.pl/articles/2048759.pdf
Data publikacji:
2019
Wydawca:
Instytut Włókien Naturalnych i Roślin Zielarskich
Tematy:
Humulus lupulus L.
DPPH
Folin-Ciocalteu method
FRAP
antioxidants
ultrasoundassisted extraction
metoda Folin-Ciocalteu
antyoksydanty
ekstrakcja wspomagana ultradźwiękami
Opis:
Introduction: Hop (Humulus lupulus L.) is a common plant in Europe, with many beneficial health effects. In addition to the use in brewing, hops are a valuable source of active substances used in conventional and folk medicine, such as humulones and lupulones, as well as antioxidants, including phenolic compounds. Objective: The aim of the study was to evaluate and compare the antioxidant activity of alcoholic extracts of fresh hop leaves collected in 2017 and 2018. Material and methods: The raw material consisting of fresh hop leaves was extracted using ultrasoundassisted extraction. Methyl, ethyl and isopropyl alcohol at three concentrations were used as extractants. The antioxidant activity of extracts was determined using DPPH and FRAP methods. Total phenolic content was evaluated using the Folin-Ciocalteu technique. Results: All the extracts showed antioxidant potential as well as the phenolic content. Regardless of the harvesting year and methods of evaluation, the highest antioxidant activity and the total polyphenol content were observed for extracts prepared in undiluted methanol, obtained during one hour lasting extraction. Conclusion: The results of the studies have suggested that hop leaves can be a potential source of healthpromoting antioxidants.
Źródło:
Herba Polonica; 2019, 65, 3; 1-9
0018-0599
Pojawia się w:
Herba Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
COMPARISON OF ARTIFICIAL HYDROPHILIC AND LIPOPHILIC MEMBRANES AND HUMAN SKIN TO EVALUATE NIACINAMIDE PENETRATION IN VITRO
Autorzy:
Nowak, Anna
Church, Martin K.
Duchnik, Wiktoria
Różewicka-Czabańska, Monika
Bielecka-Grzela, Stanisława
Prowans, Piotr
Pietriczko, Jan
Czapla, Norbert
Bargiel, Piotr
Klimowicz, Adam
Powiązania:
https://bibliotekanauki.pl/articles/895721.pdf
Data publikacji:
2020-04-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
penetration
Franz diffusion cell
Niacinamide (Vitamin B3)
artificial membrane
human skin
Opis:
The evaluation of skin penetration of active substances from topical preparations is a pre-clinical requirement in the pharmaceutical industry. While in vitro preparations of human or animal skin are frequently used the development of artificial lipophilic and hydrophilic membranes with similar properties to human or animal skin need to be developed. This preliminary study compared the in vitro permeation of niacinamide (vitamin B3), which is used as a model drug, across artificial hydrophilic and lipophilic membranes with iv vitro penetration across human skin. The experiments were carried out in Franz diffusion cells. Artificial membranes were filter paper impregnated with either collodium (hydrophilic), stearic acid, cetyl alcohol or cetyl alcohol + cholesterol (lipophilic). Acidic and neutral hydrogel and emulsion (pH 5.4 and 7.4) containing 0.5% of niacinamide were applied to membranes for up to 4 hours. Niacinamide permeated hydrophilic better than lipophilic membranes. There were no significant differences between the cumulated amounts of niacinamide that penetrated artificial lipophilic membranes consisting of, stearic acid, cetyl alcohol and cholesterol as compared with human skin in vitro. Also, hydrogel and emulsion solvents gave similar results. In conclusion, these artificial membranes seem to be a promising alternative to human or animal skin.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 271-279
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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