- Tytuł:
- The importance of liver lesions and changes to biochemical and coagulation factors in the pathogenesis of RHD
- Autorzy:
-
Trzeciak-Ryczek, Alicja
Tokarz-Deptuła, Beata
Deptuła, Wiesław - Powiązania:
- https://bibliotekanauki.pl/articles/1039081.pdf
- Data publikacji:
- 2015
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
rabbit
RHDV
biochemical factors
coagulation factors - Opis:
- RHDV (rabbit haemorrhagic disease virus) is an etiologic factor of RHD (rabbit haemorrhagic disease), which is highly morbid and mortal viral infection of an adult European rabbit. Although three decades have passed since the first outbreak of rabbit haemorrhagic disease, the pathogenesis of RHD has still not been fully elucidated. It is known that RHDV replicates in the liver within the first hours following infection, causing necrotic and apoptotic cell death of hepatocytes. Anatomopathological changes are also observed in other organs of infected rabbits, i.e. lungs, spleen, kidneys, heart, as well as central nerve system. These changes leading to animals death are predominantly caused by systemic hemorrhagic diathesis with disseminated intravascular coagulation (DIC), appearing most likely as a consequence of liver cell loss through RHDV-induced apoptosis. In this paper, we presented previously described changes in biochemical and coagulation factors in RHDV infection.
- Źródło:
-
Acta Biochimica Polonica; 2015, 62, 2; 169-171
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł