- Tytuł:
-
Enzymatyczne i chemiczne modyfikacje fosfolipidów
Enzymatic and chemical modifications of phospholipids - Autorzy:
-
Chojnacka, Anna
Niezgoda, Natalia - Powiązania:
- https://bibliotekanauki.pl/articles/27310043.pdf
- Data publikacji:
- 2023
- Wydawca:
- Polskie Towarzystwo Chemiczne
- Tematy:
-
fosfolipidy strukturyzowane
koniugaty fosfolipidowe
bioaktywne kwasy tłuszczowe
modyfikacje fosfolipidów
sprzężony kwas linolowy
dehydroepiandrosteron
niesteroidowe leki przeciwzapalne
lipaza
fosfolipaza
structured phospholipids
phospholipid conjugates
bioactive fatty acids
phospholipid modification
dehydroepiandrosterone
NSAIDs
lipase
phospholipase - Opis:
- At the moment, phospholipids are among the most interesting molecules. The possibilities of chemical and enzymatic modifications, while maintaining their integrity and unique nature, also contribute to these compounds' great interest. This review paper concerns the preparation of new phospholipid conjugates containing fragments of biologically active compounds not found naturally in phospholipids, and phospholipids enriched with specific fatty acids with health-promoting properties (structured phospholipids). Chemical methods for the synthesis of phospholipids containing conjugated linolenic acid (CLA), dehydroepiandrosterone (DHEA) or selected non-steroidal anti-inflammatory drugs (NSAIDs) at the sn-1 and/or sn-2 position have been described. In addition, the evaluation of the antiproliferative activity of the obtained conjugates against selected cancer cell lines was also described. Enzymatic methods of modifying natural phospholipids leading to their enrichment with bioactive polyunsaturated fatty acids and conjugated acids have also been described.
- Źródło:
-
Wiadomości Chemiczne; 2023, 77, 5-6; 449--477
0043-5104
2300-0295 - Pojawia się w:
- Wiadomości Chemiczne
- Dostawca treści:
- Biblioteka Nauki
Artykuł