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    Wyświetlanie 1-3 z 3
    Tytuł:
    Development of an automation system for iodine-125 brachytherapy seed encapsulated by Nd:YAG laser welding
    Autorzy:
    Somessari, S. L.
    Feher, A.
    Sprenger, F. E.
    Rostelato, M. E. C. M.
    da Costa, F. E.
    Calvo, W. A. P.
    Powiązania:
    https://bibliotekanauki.pl/articles/147664.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    iodine-125 seeds
    prostate cancer
    brachytherapy
    Nd:YAG laser welding
    Opis:
    The aim of this work is to develop an automation system for iodine-125 radioactive seed production by Nd:YAG laser welding, which has been used successfully in low dose rate (LDR) brachytherapy treatment. This small seed consists of a welded titanium capsule, with 0.8 mm in diameter and 4.5 mm in length, containing iodine-125 adsorbed onto a silver rod. The iodine-125 seeds are implanted into the human prostate to irradiate the tumor for cancer treatment. Nowadays, the Radiation Technology Center, at Institute for Nuclear and Energy Research, Săo Paulo, Brazil (IPEN-CNEN/SP) imports and distributes 36,000 iodine-125 seeds per year, for the clinics and hospitals in the country. However, the Brazilian market potential is now over 8,000 iodine-125 seeds per month. The local production of these iodine-125 radioactive sources became a priority for the Institute, in order to reduce the price and the problems of prostate cancer management. It will permit to spread their use to a larger number of patients in Brazil. On the other hand, the industrial automation plays an important role for iodine-125 seeds in order to increase the productivity, with high quality and assurance, avoiding human factors, implementing and operating with good manufacturing practices (GMP). The technology consists of appliance electronic and electro-mechanical parts and components to control machines and processes. The automation system technology for iodine-125 seed production developed in this work was mainly assembled employing a programmable logic controller (PLC), a stepper motor, an Nd:YAG laser welding machine and a supervisory. The statistical repeatability of correctly encapsulated sealed sources with this automation system is greater than 95 per cent.
    Źródło:
    Nukleonika; 2011, 56, 4; 369-374
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A study about the measurement method of the homogeneity of radioactivity along an iridium-192 wire used in brachytherapy
    Autorzy:
    Costa, O. L.
    Calvo, W. A. P.
    Zeituni, C. A.
    Rostelato, M. E. C. M.
    Moura, J. A.
    Feher, A.
    Souza, C. D.
    Somessari, S. L.
    Powiązania:
    https://bibliotekanauki.pl/articles/148238.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    iridium-192
    iridium wire
    low dose rate brachytherapy
    quality control
    cancer treatment
    radioactive sources production
    Opis:
    The Nuclear and Energy Research Institute has produced, since 1998, iridium-192 wires used in low dose rate brachytherapy. In the paper the authors studied the influence of wire profile on the homogeneity distribution of radioactivity of iridium-192 along the wire. The authors propose the improvements in the quality control procedure that will provide more accurate measurement data and suggest changes in control devices.
    Źródło:
    Nukleonika; 2014, 59, 1; 37-39
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Development of an irradiation system for a small size continuous run multipurpose gamma irradiator
    Autorzy:
    Calvo, W. A. P.
    Rela, P. R.
    Napolitano, C. M.
    Kodama, Y.
    Omi, N. M.
    da Costa, F.
    de Andrade e Silva, L. G.
    Powiązania:
    https://bibliotekanauki.pl/articles/148041.pdf
    Data publikacji:
    2009
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    multipurpose irradiator
    gamma irradiator
    compact irradiator
    cobalt-60 irradiator
    gamma facility
    Opis:
    The Radiation Technology Center from IPEN-CNEN/SP, Brazil, developed a revolutionary design and national technology, a small-sized continuous run and multipurpose industrial gamma irradiator, to be used as a demonstration facility for manufacturers and contract service companies, which need economical and logistical in-house irradiation system alternatives. Also, to be useful for supporting the local scientific community on development of products and process using gamma radiation, assisting the traditional and potential users on process validation, training and qualification of operators and radioprotection officers. The developed technology for this facility consists of a continuous tote box transport system, comprising a single concrete vault, where the automated transport system of products inside and outside of the irradiator utilizes a rotating door, integrated with the shielding, avoiding the traditional maze configuration. Covering 76 m2 of floor area, the irradiator design is a product overlap sources and the maximum capacity of cobalt-60 wet sources is 37 PBq. The performed qualification program of this multipurpose irradiator was based on AAMI/ISO 11137 standard, which recommends the inclusion of the following elements: installation and process qualification. The initial load of the multipurpose irradiator was 3.4 PBq with 13 cobalt-60 sources model C-188, supplied by MDS Nordion – Canada. For irradiator dose optimization, the source distribution was done using the software Cadgamma developed by IPEN-CNEN/SP. The polymethylmetacrylate (PMMA) dosimeter system, certified by the International Dose Assurance Service (IDAS) of the International Atomic Energy Agency (IAEA) was used for irradiator dose mapping. The economic analysis, performance concerning with dose uniformity and cobalt-60 utilization efficiency were calculated and compared with other commercial gamma irradiators available on the market.
    Źródło:
    Nukleonika; 2009, 54, 2; 93-97
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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