- Tytuł:
- Image analysis of immunohistochemical stains for detection of parathyroid disease
- Autorzy:
-
Płaczek, B.
Orczyk, T.
Bułdak, R.
Michalski, M.
Segiet, O.
Polaniak, R. - Powiązania:
- https://bibliotekanauki.pl/articles/333291.pdf
- Data publikacji:
- 2015
- Wydawca:
- Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
- Tematy:
-
image processing
immunohistochemistry
hyperparathyroidism
light microscopy
przetwarzanie obrazu
immunohistochemia
nadczynność przytarczyc
mikroskopia świetlna - Opis:
- In this paper a method is introduced which enables automatic detection of parathyroid hyperplasia and parathyroid adenoma on the basis of immunohistochemical angiogenesis markers expression in micrographs. The proposed method uses digital image processing techniques and classification algorithms to detect diseased tissue. The disease detection is performed by classification of normalized color intensity histograms. Accuracy of this method was evaluated by using micrographs of parathyroid tissue sections obtained from patients that have undertaken surgery due to primary hyperparathyroidism. Use of different color models, various classifiers, and immunohistochemical markers was considered during the experiments. The experimental results show that the introduced method enables accurate detection of parathyroid disease. The most promising results were obtained for k-nearest neighbor and neural network classifiers.
- Źródło:
-
Journal of Medical Informatics & Technologies; 2015, 24; 141-146
1642-6037 - Pojawia się w:
- Journal of Medical Informatics & Technologies
- Dostawca treści:
- Biblioteka Nauki
Artykuł