- Tytuł:
- Mesenchymal stem cells for the treatment of complex perianal fistulas in patients with Crohn disease
- Autorzy:
-
Borycka-Kiciak, Katarzyna
Pietrzak, Anna
Kielar, Maciej
Tarnowski, Wiesław - Powiązania:
- https://bibliotekanauki.pl/articles/1391853.pdf
- Data publikacji:
- 2020
- Wydawca:
- Index Copernicus International
- Tematy:
-
Crohn’s disease
inflammatory bowel disease
mesenchymal stem cells
perianal fistula
treatment - Opis:
- Treatment of perianal fistulizing Crohn’s disease is demanding and burdened with a high percentage of failures, which forces clinicians to search for new, more effective therapeutic options. One of these options is the use of adipose-derived mesenchymal stem cells in local administration. Due to their multipotentiality and complex mechanism of action, stem cells are the promising new therapeutic approach for the treatment-refractory complex perianal fistulas – demonstrating both high efficacy and a favorable safety profile. The paper presents current knowledge on the mechanisms of action and manner of administration of mesenchymal stem cells, as well as the effectiveness and safety of their use in the treatment of perianal Crohn’s disease based on available literature.
- Źródło:
-
Polish Journal of Surgery; 2020, 92, 1; 38-47
0032-373X
2299-2847 - Pojawia się w:
- Polish Journal of Surgery
- Dostawca treści:
- Biblioteka Nauki
Artykuł