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    Wyświetlanie 1-3 z 3
    Tytuł:
    Lycopene activity on lung and kidney cancer cells by T2 relaxation time 1 H Magnetic Resonance Imaging in vitro
    Autorzy:
    Pogoda, Katarzyna
    Pucka, Maria
    Tabarkiewicz, Jacek
    Bober, Zuzanna
    Aebisher, David
    Galiniak, Sabina
    Bartusik-Aebisher, Dorota
    Powiązania:
    https://bibliotekanauki.pl/articles/454731.pdf
    Data publikacji:
    2020-03-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    cell cultures
    lung cancer
    lycopene
    kidney cancer
    magnetic resonance imaging relaxation times
    Opis:
    Introduction. The paper presents the results of a study of cell cultures of lung cancer and kidney cancer using lycopene performed using clinical magnetic resonance imaging. Aim. The aim of the study was to evaluate lycopene activity on tumor cell cultures. Material and methods. For this purpose, MR tests were performed using the technique of determining transverse relaxation. Results. Described here studies demonstrated that lycopene may inhibit the growth of A549 and ACHN cell lines. Conclusion. We determine changes in spin lattice relaxavity T2 to monitor treatment of lung cancer cell line A549 and kidney cancer cell line ACHN cells treatment with lycopene.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2020, 1; 5-9
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Infliximab MRI relaxation time in solution
    Autorzy:
    Bober, Zuzanna
    Bar, Piotr
    Pasternak, Grzegorz
    Galiniak, Sabina
    Bartusik-Aebisher, Dorota
    Filip, Rafał
    Aebisher, David
    Powiązania:
    https://bibliotekanauki.pl/articles/454757.pdf
    Data publikacji:
    2019
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    infliximab
    magnetic resonance imaging relaxation time
    Opis:
    Introduction. The use of Quantitative Magnetic Resonance Imaging to drug monitoring in vitro or in vivo can provides a powerful means to map the effects of drugs on tissue activity. Aim. The purpose of this study was to measure relaxation time of antibody phantom. For this purpose, infliximab sample was used. Material and methods. The selected methods to detect relaxation time of antibody was Magnetic Resonance Imaging technique. We detected spin-lattice (T1 ) relaxation time and discuss differences where compare to water. Results. The measurements ofspin-lattice (T1 ) relaxation time showed significant differences. The results obtained in phantom indicate that we can use this result for measurements of relaxation time in vitro. Conclusion. Infliximab is approved for severe cases of rheumatoid arthritis, together with methotrexate, for pronounced psoriasis and psoriasis-arthritis, ankylosing spondylitis as well as for chronic inflammatory bowel disease. We conclude, that Quantitative Magnetic Resonance Imaging can be used to monitor drug effects
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2019, 1; 22-25
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cytisine parameters measured in the 1.5 Tesla magnetic field
    Autorzy:
    Bober, Zuzanna
    Galiniak, Sabina
    Leksa, Dawid
    Dynarowicz, Klaudia
    Aebisher, David
    Ostańska, Elżbieta
    Czmil, Anna
    Bar, Piotr
    Bartusik-Aebisher, Dorota
    Tutka, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/454807.pdf
    Data publikacji:
    2020-03-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    cytisine
    desmoxan
    magnetic resonance imagin
    tabex
    Opis:
    Introduction. Cytisine, Cytisinum (C11H14N2O), is an organic chemical compound. Cytisine is heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. Aim. The aim of the study is to measure the influence of water on the form of drug in the magnetic field 1.5 Tesla. Material and methods. For this purpose, magnetic resonance imaging tests were performed to check the solubility of pure cytisine, Desmoxan tablets and Tabex capsules. Results. From a pharmacological point of view, both Desmoxan tablets and Tabex capsules should exert the same effect on the human body, this is due to the identical content of the active substance, in this case cytisine (1.5 mg). Conclusion. The differences in the results obtained may be related to additional excipients that contain medications, but it is believed that they should not have a negative impact on the action of the active substances.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2020, 1; 16-19
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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