- Tytuł:
- Hepatitis C - new developments in the studies of the viral life cycle
- Autorzy:
-
Rychłowska, Małgorzata
Bieńkowska-Szewczyk, Krystyna - Powiązania:
- https://bibliotekanauki.pl/articles/1040855.pdf
- Data publikacji:
- 2007
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
hepatitis C virus
HCV replicons
HCVcc-cell culture-derived
HCV pseudoparticles - Opis:
- Hepatitis C virus (HCV) is a causative agent of chronic liver disease leading to cirrhosis, liver failure and hepatocellular carcinoma. The prevalence of HCV is estimated as 3% of the world population and the virus is a major public health problem all over the world. For over 16 years, since HCV had been discovered, studies of the mechanisms of the viral life cycle and virus-host interactions have been hampered by the lack of a cell culture system allowing the virus to be grown in laboratory conditions. However, in recent years some new model systems to study HCV have been developed. The major breakthrough of the last two years was the cell culture system for maintaining the virus in an adapted hepatocyte-derived cell line. This review describes the techniques and applications of most of the in vitro systems and animal models currently used for working with hepatitis C virus.
- Źródło:
-
Acta Biochimica Polonica; 2007, 54, 4; 703-715
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł