- Tytuł:
- Solubility of a pharmacological intermediate drug Isatin in different solvents at various temperatures
- Autorzy:
-
Baluja, S.
Bhalodia, R.
Bhatt, M.
Vekariya, N.
Gajera, R. - Powiązania:
- https://bibliotekanauki.pl/articles/412531.pdf
- Data publikacji:
- 2013
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
Isatin
solubility
Thermodynamic parameters - Opis:
- The solubility of isatin in different solvents was studied by a gravimetrical method from (298.15 to 318.15) K under atmospheric pressure and the solubility data were correlated against temperature. The solvents selected for the present study are: water, methanol, ethanol, 1-butanol, dichloromethane, dichloroethane, chloroform and carbon tetra chloride. Among chlorinated solvents, solubility is observed to be maximum in 1, 2-dichloroethane and minimum in dichloromethane whereas in alcohols, maximum solubility is observed in methanol. In water, solubility is found to be minimum. Further, some thermodynamic parameters such as Gibb’s energy (ΔGsol), heat of solution (ΔHsol) and entropy of solution (ΔSsol) have also been evaluated.
- Źródło:
-
International Letters of Chemistry, Physics and Astronomy; 2013, 12; 36-46
2299-3843 - Pojawia się w:
- International Letters of Chemistry, Physics and Astronomy
- Dostawca treści:
- Biblioteka Nauki