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Tytuł:
Functional MRI – how does it work?
Autorzy:
Truszkiewicz, Adrian
Aebisher, David
Przypek, Aneta
Guz, Wiesław
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454947.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
deoxyhemoglobin
oxyhemoglobin
Magnetic Resonance Imaging functional Magnetic Resonance Imaging
Opis:
Magnetic Nuclear Resonance (MRI) is a non-invasive tissue imaging method. This technique is based on the influence of a strong magnetic field and electromagnetic wave of strictly defined frequency on the nucleus of elements with non-zero spin. The study describes one of the variants of functional MRI, (fMRI), which has become a key technique in brain imaging. This technique has excellent spatial and temporal resolution and involves a changing signal intensity depending on the degree of oxygenation of the blood. Blood oxygenation levels are known to vary in accordance with neural activity and these differences can be used to detect brain activity. This is due to increased demand for energy and oxygen in the area of increased neural activity. The basis of this imaging is the so-called Blood Oxygenation-Level Dependent (BLOD) effect. The aim of this paper is to present the scope of fMRI as a diagnostic method in neurology and in neurosurgery. This paper presents the principles of fMRI, methods of application, research result development, and suggests areas of possible medical applications. The limitations of fMRI as a clinical tool in medical applications will also be addressed. Studies presented in this paper are based on clinical fMRI experience and a literature review.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 2; 120-126
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Infliximab MRI relaxation time in solution
Autorzy:
Bober, Zuzanna
Bar, Piotr
Pasternak, Grzegorz
Galiniak, Sabina
Bartusik-Aebisher, Dorota
Filip, Rafał
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/454757.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
infliximab
magnetic resonance imaging relaxation time
Opis:
Introduction. The use of Quantitative Magnetic Resonance Imaging to drug monitoring in vitro or in vivo can provides a powerful means to map the effects of drugs on tissue activity. Aim. The purpose of this study was to measure relaxation time of antibody phantom. For this purpose, infliximab sample was used. Material and methods. The selected methods to detect relaxation time of antibody was Magnetic Resonance Imaging technique. We detected spin-lattice (T1 ) relaxation time and discuss differences where compare to water. Results. The measurements ofspin-lattice (T1 ) relaxation time showed significant differences. The results obtained in phantom indicate that we can use this result for measurements of relaxation time in vitro. Conclusion. Infliximab is approved for severe cases of rheumatoid arthritis, together with methotrexate, for pronounced psoriasis and psoriasis-arthritis, ankylosing spondylitis as well as for chronic inflammatory bowel disease. We conclude, that Quantitative Magnetic Resonance Imaging can be used to monitor drug effects
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 1; 22-25
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Magnetic Resonance Elastography – noninvasive method to assess liver disease
Autorzy:
Ożóg, Łukasz
Aebisher, David
Bober, Zuzanna
Bartusik-Aebisher, Dorota
Guz, Wiesław
Cholewa, Marian
Powiązania:
https://bibliotekanauki.pl/articles/454714.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
fibrosis
liver stiffness
MRE
magnetic resonance imaging
Opis:
Currently, liver disease is widespread and the awareness of these diseases is low. Early symptoms of liver disease do not necessarily indicate problems with this organ and patients are usually informed of their problems when the stage of the disease is already advanced. Invasive biopsies are the clinical diagnostic method most commonly used in the evaluation of liver disease. A biopsy is associated with a high risk of false results and additional complications. Finding new non-invasive imaging methods has led to the discovery of a new method called Magnetic Resonance Elastography (MRE). This technique allows one to evaluate the mechanical properties of tissues and to distinguish between pathological states. Testing using this technique can be performed on a conventional magnetic resonance system by using few additional components and properly prepared software. Studies have shown that there is a strong correlation between MRE-measured liver stiffness and the degree of fibrosis. MRE is also useful in characterizing liver tumors. Studies show that this technique is highly credible in both health volunteers and patients with liver fibrosis. MRE has tremendous diagnostic potential. The described technique is not currently widely used and has the 127-132potential to serve as a safe and accurate alternative in clinical diagnostics in the future.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 2; 127-132
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Glycosaminoglycan concentration in cancer tissue
Autorzy:
Bar, Piotr
Galiniak, Sabina
Bartusik-Aebisher, Dorota
Filip, Rafał
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/454799.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
fixed charge density glycosaminoglyca
magnetic resonance imaging
Opis:
Introduction. Glycosaminoglycans (GAGs) play a widespread role in tissue modelling. GAG polymers may affect several receptor pathways in parallel. Aim. To present difference in concentration of GAG in healthy and cancer tissues. Material and methods. The literature search was performed nd reviewed using selected keywords. Results. We revieved the methods of detection various types of glycans measured by Magnetic Resonance Imaging. Conclusion. MRI methodology provides an efficient tool forstudy of cellular composition. The use T1 aof T2 measurements to study cancer tissue is a promising assay.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 2; 175-178
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
19F MRI As a tool for imaging drug delivery to tissue and individual cells
Autorzy:
Bober, Zuzanna
Aebisher, David
Ożóg, Łukasz
Tabarkiewicz, Jacek
Tutka, Piotr
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454941.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
drug delivery
drug tracking
fluorine
magnetic resonance imaging
Opis:
Over the past few decades, magnetic resonance imaging (MRI) has proven to be extremely successful in medical applications. More recently, the biomedical applications of MRI have been gaining more use in the field of clinical pharmacy. In 1977, perfluorocarbon compounds (PFC), which form emulsions that can carry drugs, were analyzed by 19F MRI and emulsified PFC compounds have been investigated as potential blood substitutes since the early 1960s and now a wide variety of PFC compounds are currently available as 19F MRI biomarkers. Molecules with 19F substituents are particularly attractive for use in drug tracking by 19F MRI due to 100% 19F abundance, high 19F MRI sensitivity (0.83 relative to 1H MRI) and an impressively large chemical shift range (400 ppm). Another benefit in the use of 19F MRI is a zero background signal in biological samples due to lack of endogenous fluorine. Therefore, drugs containing fluorine atom have potential for 19F MRI imaging drug delivery to tissue. This article will review recent developments in the use of 19F MRI in imaging drug delivery to tissue and individual cells.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 2; 99-109
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
MRI as a potential tool for monitoring of therapeutic monoclonal antibody distribution in cancer patients
Autorzy:
Tabarkiewicz, Jacek
Aebisher, David
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/895617.pdf
Data publikacji:
2020-06-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
monoclonal antibody
magnetic resonance imaging
fluorine
cancer diagnostics
Opis:
Imaging and quantification of MAbs distribution by MRI after administration in vivo can improve patient outcomes, although it is not routinely used in the clinic hence the motivation for development of new MAbs imaging methodologies. Improvements in imaging and quantification of antibody distributions can be made by conjugating MAbs to “hotspot” atoms such as 19F as 19F Currently, research investigating the incorporation of 19F to antibody delivery systems has been limited to trastuzumab perfluorocarbon emulsions and this method has not been extended to other clinically approved antibodies. The methodologies of 19F MRI can improve current limitations of antibody immunotherapy such as quantitative visualization of targeted surface antigens expressed on tumor cells.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 3; 383-389
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Investigation of pharmaceuticals by nuclear magnetic resonance imaging and spectroscopy
Autorzy:
Bober, Zuzanna
Aebisher, David
Tabarkiewicz, Jacek
Guz, Wiesław
Tutka, Piotr
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454783.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
drug delivery systems
drug forms
magnetic resonance imaging pharmaceuticals
Opis:
Currently, new and easier ways of analyzing pharmaceutical drug forms and drug delivery mechanisms are being sought. Magnetic resonance imaging (MRI) is a non-invasive imaging technique that images drug forms such as tablets, liquids and topicals and drug form behavior in living organisms on both the tissue and cellular scale. The advantages of MRI include noninvasiveness, variable sample capacity and ease of transfer of phantom results to in vitro and in vivo studies. This review concerns the usefulness of clinical MRI that cannot be understated as this technique provides non-invasive and non-destructive insight into the properties of drug delivery systems. The research discussed here concerns the use of magnetic resonance, spectroscopy and chromatography to investigate selected pharmaceuticals and covers work of selecting drugs and antibodies for modification by synthesis for evaluation by MRI. Modifications have been aimed at improving therapeutic efficacy, delivery, and MRI. Modification conditions such as (pH, concentration, temperature, and the influence of other components present in the solutions) will be discussed to understand drug delivery system improvements and the reliability and repeatability of the results obtained. We hope to explore and expand the scope of pharmaceutical imaging with MRI for application in clinical medicine.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 2; 110-119
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Contrast-enhanced Magnetic Resonance Imaging of lung cell cultures
Autorzy:
Bober, Zuzanna
Pogoda, Katarzyna
Aebisher, David
Tabarkiewcz, Jacek
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/895529.pdf
Data publikacji:
2020-04-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Lung cancer
cell cultures
magnetic resonance imaging
contrast media
Gadolinium
Opis:
Lung cancer is one of the most common types of cancer diagnosed, and the development of methods to image diseased lung tissue by MRI is of utmost importance. Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) was used to noninvasively evaluate spin-spin relaxation time, T1, of lung cell cultures infused with various clinical gadolinium-based contrast media for imaging. In this study we used a clinical 1.5 Tesla scanner and the contrast agents: Omniscan, MultiHance, Gadovist and ProHance. A significant five-fold reduction of T1 relaxation time was obtained.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 251-258
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Paradygmaty w fMRI
Paradigms in fMRI
Autorzy:
Leksa, Natalia
Truszkiewicz, Adrian
Aebisher, David
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/2146758.pdf
Data publikacji:
2020
Wydawca:
Indygo Zahir Media
Tematy:
fMRI
paradygmaty
funkcjonalny rezonans magnetyczny
paradigms
functional magnetic resonance imaging
Opis:
Funkcjonalny Rezonans Magnetyczny (fMRI) jest nieinwazyjną techniką badawczą, która daje wgląd w procesy zachodzące w mózgu pacjenta. Przy jego pomocy ocenia się zarówno miejsca odpowiedzialne za motorykę, jak i funkcje poznawcze. Ta metoda badawcza oparta o własności magnetyczne oksyhemoglobiny i deoksyhemoglobiny zapewnia identyfikacje ośrodków mózgowia w sposób do tej pory niemożliwy. Jej stosowanie jest ważne nie tylko w procesie poznawczym, ale również w procesie leczenia, w szczególności w procesie przygotowywania pacjentów do zabiegów operacyjnych. FRMI należy do diagnostyki szczególnie wymagającej współpracy ze strony pacjenta, ponieważ najczęściej musi on realizować zadania narzucone przez personel badający. To właśnie od właściwego zaprojektowania tychże zadań i schematu czasowego ich realizacji i oceny wyników zależy właściwa diagnostyka. Celem niniejszej pracy jest prezentacja wybranych paradygmatów stosowanych w FMRI.
Functional Magnetic Resonance Imaging (fMRI) is a non-invasive research technique that gives insight into the processes in the patient’s brain. With its help, both the places responsible for motor skills and cognitive functions are assessed. This research method based on the magnetic properties of oxyhemoglobin and deoxyhemoglobin ensures identification of brain centers in a way that has not been possible so far. FRMI use is important not only in the cognitive process, but also in the treatment process, in particular in the process of preparing patients for surgery. FRMI belongs to the diagnostics particularly demanding cooperation on the part of the patient, because he most often has to carry out tasks imposed by the research staff. It is the proper design of these tasks and the time schedule of their implementation and evaluation of results that determine the correct diagnosis. The purpose of this work is to present selected paradigms used in FMRI.
Źródło:
Inżynier i Fizyk Medyczny; 2020, 9, 2; 109--112
2300-1410
Pojawia się w:
Inżynier i Fizyk Medyczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The usefulness of relaxation time using MRI measurements
Autorzy:
Bober, Zuzanna
Aebisher, David
Truszkiewicz, Adrian
Ożóg, Łukasz
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454698.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
Magnetic Resonance Imaging
T1 relaxation
field strength 1.5 Tesla
Opis:
Introduction. Magnetic Resonance Imaging methods are now frequently used for the analysis of the diseased tissue. These methods are based on the fact that the spin-lattice, T1 , and the spin-spin, T2 , relaxation times are different in diseased tissue as compared to that of normal tissue. Aim. Here we present measurements of spin-lattice relaxation time T1 on a Magnetic Resonance Imaging scaner with field strength 1.5 Tesla. Material and methods. Measurements of T1 relaxation time and analysis of literature. Results. We provide procedure for measurements of T1 relaxation time with field strength 1.5 Tesla and present a discussion of current applications.
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 3; 224-227
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Radio Frequency MRI coils
Autorzy:
Truszkiewicz, Adrian
Aebisher, David
Bober, Zuzanna
Ożóg, Łukasz
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454860.pdf
Data publikacji:
2020-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
field strength 1.5 Tesla
magnetic resonance imaging
radio frequency coil
Opis:
Introduction. Magnetic Resonance Imaging (MRI) coils technology is a powerful improvement for clinical diagnostics. This includes opportunities for mathematical and physical research into coil design. Aim. Here we present the method applied to MRI coil array designs. Material and methods. Analysis of literature and self-research. Results. The coils that emit the radiofrequency pulses are designed similarly. As much as possible, they deliver the same strength of radiofrequency to all voxels within their imaging volume. Surface coils on the other hand are usually not embedded in cylindrical surfaces relatively close to the surface of the body. Conclusion. The presented here results relates to the art of magnetic resonance imaging (MRI) and RF coils design. It finds particular application of RF coils in conjunction with bore type MRI scanners.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 1; 24-27
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Perspektywy badań mózgowia z wykorzystaniem MRI
Prospects for brain research using MRI
Autorzy:
Truszkiewicz, Adrian
Dynarowicz, Klaudia
Bartusik-Aebisher, Dorota
Cholewa, Marian
Powiązania:
https://bibliotekanauki.pl/articles/985830.pdf
Data publikacji:
2020
Wydawca:
Indygo Zahir Media
Tematy:
rezonans magnetyczny
sekwencje
badanie OUN
magnetic resonance imaging
sequences
CNS examination
Opis:
Rezonans magnetyczny (MRI) zmodyfikował praktykę radiologii w dziedzinie badań mózgowia. Technika ta opiera się na bezpiecznej interakcji pomiędzy falami radiowymi o określonej częstotliwości i jądrami wodoru w ciele człowieka lub w innym badanym obiekcie. Szczególny postęp zaobserwowano w badaniach ilościowych i jakościowych metabolitów, które z definicji nie są zaburzeniami ośrodkowego układu nerwowego i które nie są spowodowane nieprawidłowościami strukturalnymi, dlatego występują endogennie w niewielkich ilościach. W pracy przedstawiono pogląd na obecne wykorzystanie MRI w badaniach mózgowia.
Magnetic resonance imaging (MRI) has modified radiology in the field of brain research. This technique is based on the safe interaction between radio waves of a certain frequency and hydrogen nuclei in the human body or other object being tested. Particular progress has been observed in the quantitative and qualitative studies of metabolites which by definition are not disorders of the central nervous system, and which are not caused by structural abnormalities and therefore occur in small amounts enodogenously. The paper presents the view on the current use of MRI in brain research.
Źródło:
Inżynier i Fizyk Medyczny; 2020, 9, 1; 21-22
2300-1410
Pojawia się w:
Inżynier i Fizyk Medyczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lycopene activity on lung and kidney cancer cells by T2 relaxation time 1 H Magnetic Resonance Imaging in vitro
Autorzy:
Pogoda, Katarzyna
Pucka, Maria
Tabarkiewicz, Jacek
Bober, Zuzanna
Aebisher, David
Galiniak, Sabina
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454731.pdf
Data publikacji:
2020-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
cell cultures
lung cancer
lycopene
kidney cancer
magnetic resonance imaging relaxation times
Opis:
Introduction. The paper presents the results of a study of cell cultures of lung cancer and kidney cancer using lycopene performed using clinical magnetic resonance imaging. Aim. The aim of the study was to evaluate lycopene activity on tumor cell cultures. Material and methods. For this purpose, MR tests were performed using the technique of determining transverse relaxation. Results. Described here studies demonstrated that lycopene may inhibit the growth of A549 and ACHN cell lines. Conclusion. We determine changes in spin lattice relaxavity T2 to monitor treatment of lung cancer cell line A549 and kidney cancer cell line ACHN cells treatment with lycopene.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 1; 5-9
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The larynx cancer in vitro study by MRI relaxtion time of water
Autorzy:
Domka, Wojciech
Ożóg, Łukasz
Bartusik-Aebisher, Dorota
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/2038279.pdf
Data publikacji:
2020-09-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
larynx tissue
magnetic resonance imaging
T2 mapping
T2 relaxation time
Opis:
Introduction. Squamous cell carcinoma (SCC) of the larynx accounts for a significant percentage of all head and neck cancers. Aim. In this paper we determine the differences in magnetic resonance relaxation time (MRI) of water in cancerous and healthy larynx tissues. Material and methods. This study is aimed on T2 MRI modalities for monitoring morphology of larynx tissue. Results. Our results showed that T2 MRI relaxation time measured in larynx tissue can be used to assess early cancer condition of larynx tissues. The changes of T2 MRI correspond to tumor growth within normal tissue. Conclusion. The study showed potential of MRI for the non-invasive monitoring of larynx condition.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 3; 185-187
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena przydatności średniopolowych systemów MR w obrazowaniu hodowli komórkowych
Assessment of the usefulness of medium-field MR systems in imaging of cell cultures
Autorzy:
Truszkiewicz, Adrian
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/985832.pdf
Data publikacji:
2020
Wydawca:
Indygo Zahir Media
Tematy:
rezonans magnetyczny
mikroskopia MRI
hodowle komórkowe
magnetic resonance imaging
MRI microscopy
cell cultures
Opis:
W niniejszym artykule autorzy podjęli próbę oceny przydatności systemów rezonansu magnetycznego o sile 1,5 Tesla do obrazowania małych struktur, jakimi są hodowle komórkowe. Zakres obrazowania, jaki stał się przedmiotem badań, wkracza w obszar będący domeną mikroskopii rezonansu magnetycznego (MRM). W dzisiejszej dobie badania te wykonywane są przy użyciu systemów wysokopolowych zapewniających dużo większe rozdzielczości przestrzenne. Celem pracy było określenie warunków, jak również parametrów skanowania pozwalających na obrazowanie małych obiektów przy wykorzystaniu systemu OPTIMA MR360 produkcji GE Healthcare. W wyniku prac koniecznym stało się opracowanie dodatkowej cewki solenoidalnej, której to zarówno wymiary, kształt, jak i konstrukcja zapewniły optymalną jakość obrazowania możliwą do uzyskania w oparciu o w/w system MR. Artykuł ten jest pierwszym z serii prac ukazujących badania hodowli komórkowych z użyciem rezonansu magnetycznego w Uniwersytecie Rzeszowskim.
In this article, the authors attempt to assess the usefulness of 1,5 Tesla magnetic resonance imaging systems for imaging of small structures such as cell cultures. The scope of imaging that has become the subject of research enters the area that is the domain of magnetic resonance microscopy (MRM). Nowadays, these tests are performed using high-field systems providing much higher spatial resolutions. The purpose of the work was to determine the conditions as well as scanning parameters that allow imaging of small objects using the OPTIMA MR360 production system. GE Healthcare. As a result of the work, it became necessary to develop an additional solenoid coil, which both dimensions, shape and design ensured optimal imaging quality possible based on the above MR system. This article is the first in a series of works showing the study of cell cultures using magnetic resonance imaging at the University of Rzeszów.
Źródło:
Inżynier i Fizyk Medyczny; 2020, 9, 1; 37-40
2300-1410
Pojawia się w:
Inżynier i Fizyk Medyczny
Dostawca treści:
Biblioteka Nauki
Artykuł
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