- Tytuł:
- Optimization of Headspace Solid Phase Microextraction Procedure for Trace Analysis of Toluene
- Autorzy:
-
Heidari, H. R.
Shahtaheri, S. J.
Golbabaei, F.
Alimohammadi, M.
Rahimi-Froushani, A. - Powiązania:
- https://bibliotekanauki.pl/articles/90998.pdf
- Data publikacji:
- 2008
- Wydawca:
- Centralny Instytut Ochrony Pracy
- Tematy:
-
headspace
solid phase microextraction
gas chromatography
toluene - Opis:
- This study describes optimization of headspace solid phase microextraction followed by gas chromatography equipped with a flame ionization detector for toluene at trace level in spiked urine. The parameters affecting the extraction and gas chromatographic determination of analytes were studied: extraction time and temperature; desorption time and temperature; addition of NaCl; and pH, volume and agitation of the sample. Optimized headspace extraction was carried out at 30 °C for 6 min in the presence of 0.2 g⋅m–1of NaCl in the sample solution. Also, sample volume and sample pH were optimized at 5 ml and 7 (neutral pH), respectively. Desorption of the analytes was carried out at 250 °C for 60 s. The optimized procedure was validated with 3 different pools of spiked urine; it showed good reproducibility over 6 consecutive days and 6 within-day experiments. The study also determined the accuracy, linearity and detection limits of this method.
- Źródło:
-
International Journal of Occupational Safety and Ergonomics; 2008, 14, 4; 395-405
1080-3548 - Pojawia się w:
- International Journal of Occupational Safety and Ergonomics
- Dostawca treści:
- Biblioteka Nauki
Artykuł