- Tytuł:
- Routine simultaneous production of no-carrier-added high purity 64Cu and 67Ga
- Autorzy:
-
Al Rayyes, A. H.
Ailouti, Y. - Powiązania:
- https://bibliotekanauki.pl/articles/147595.pdf
- Data publikacji:
- 2011
- Wydawca:
- Instytut Chemii i Techniki Jądrowej
- Tematy:
-
64Cu
targetry
radioisotope production
ion-exchange chromatography - Opis:
- A routine production method of no-carrier-added 64Cu was performed. A copper target support is electroplated by gold then an optimized thickness of enriched 68Zn layer is deposited. The 68Zn target was bombarded with a 23.5 MeV and 250 miA proton beam, generating the main nuclear reactions 68Zn(p,2n)67Ga and 68Zn(p,alfa n)64Cu. A semi-automated separation method using a chromatographic column system was developed for 64CuCl2 production. A 600 mCi batch of 64Cu is produced at the end of separation and purification chemistry. The radionuclidic purity of 64Cu was less than 98% as required by the United States and European Pharmacopoeias. Radiochemical purity and activity concentration is suitable for labeling different ligands to produce diagnostic and therapeutic radiopharmaceuticals.
- Źródło:
-
Nukleonika; 2011, 56, 4; 259-262
0029-5922
1508-5791 - Pojawia się w:
- Nukleonika
- Dostawca treści:
- Biblioteka Nauki
Artykuł