Autor: Czarnecka, J. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Enhanced cell integration to titanium-grafit composite
Autorzy:: Menaszek, E.
Ścisłowska-Czarnecka, A.
Deptuła, P.
Dąbrowski, J. R.
Powiązania:: https://bibliotekanauki.pl/articles/285876.pdf
Data publikacji:: 2010
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: composites
titanium alloys
implants
Źródło:: Engineering of Biomaterials; 2010, 13, no. 99-101; 122
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Chemical modification of poly ε-caprolactone with wollastonite and its influence on biological properties of osteoblast like-cells MG-63
Autorzy:: Ścisłowska-Czarnecka, A.
Menaszek, E.
Kołaczkowska, E.
Błażewicz, M.
Podporska, J.
Powiązania:: https://bibliotekanauki.pl/articles/284898.pdf
Data publikacji:: 2011
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: polycaprolactone
wollastonite
osteoblast-like MG-63 cells
cell adhesion
viability
proliferation
alkaline phosphatase
Opis:: PCL (poly-ε-caprolactone) is a biocompatible and biodegradable polymer of aliphatic polyester group. However, PCL does not effectively bind to the bone in contrast to bioactive inorganic compounds such as wollastonite. For this wollastonite (WS) is regarded as a potential bioactive material for bone tissue engeenering although its main drawback is brittlennes. Therefore we synthesized polymer nanocomposite materials composed of poly-ε-caprolactone and wollastonite (PCL/wollastonite) containing either 0.5% or 5% of the latter modifying filler. And we aimed to verify biological properties of the nanocomposite PCL/WS materials, in comparison to the pure PCL, on cultures of osteoblast-like cells MG-63. The study revealed that the adherence of the osteoblast-like cells to the tested materials was enhanced by the PCL modification (PCL/5WS > PCL/0.5WS > PCL) while cell viability/proliferation was not altered. Furthermore, the activity of alkaline phosphatase indicative of osteoblast differentiation (maturation) was enhanced when the cells were cultured with either PCL/5WS or PCL/0.5WS. Overall, our results indicate that PCL-modified wollastonite improves biological properties of the basic biomaterial suggesting its potential usefulness/application for the bone tissue regeneration.
Źródło:: Engineering of Biomaterials; 2011, 14, 102; 11-14
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Porous titanium scaffolds with modified surface: in vitro cell biology assessment
Autorzy:: Ścisłowska-Czarnecka, A.
Menaszek, E.
Szaraniec, B.
Chłopek, J.
Kołaczkowska, E.
Powiązania:: https://bibliotekanauki.pl/articles/285246.pdf
Data publikacji:: 2009
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: osteoblasts
cytokines
cell adherence
morphology
titanium
hydroxyapatite
bioglass
CaO-SiO2
Opis:: Interaction of host cells with a biomaterial surface is important for biocompatibility and thus is essential for biomedical applications. Therefore investigations are undertaken to scrutinize for an appropriate surface coating with physical and chemical properties minimizing undesirable activation of immunological response. For this the current study was aimed at examining the effects of different surface modifications of titanium by its coating with ceramic materials - hydroxyapatite, bioglass and CaO-SiO2on osteoblast morphology and secretory activity. Titanium is known for its excellent mechanical properties but its surface has low bioactivity. We report that CaO-SiO2coating decreased a number of attached osteoblasts and altered their morphology. Moreover, the ceramic coatings temporarily upregulated release of pro-inflammatory cytokines IL-6 (all of them) and TNF-α (CaO-SiO2). However, overall the levels of the cytokines were low. In contrast, levels of neutrophil-attracting chemokine IL-8 were the highest. IL-8 was produced mostly by cells incubated with hydroxyapatite titanium coating in contrary to those incubated with either bioglass or CaO-SiO2titanium modifications. In conclusion, the titanium coated with ceramics such as hydroxyapatite or bioglass had the best effect on cell adhesion; however, hydroxyapatite might potentially stimulate destructive neutrophils while CaO-SiO2-coating has a negative effect on cell adhesion.
Źródło:: Engineering of Biomaterials; 2009, 12, 88; 5-10
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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