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Wyszukujesz frazę "Hyaluronic Acid" wg kryterium: Temat


Wyświetlanie 1-3 z 3
Tytuł:
Artificial skin composites
Autorzy:
Ładniak, Agata
Powiązania:
https://bibliotekanauki.pl/articles/2079951.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:
titanium dioxide,
chitosan
hyaluronic acid
skin substitutes
Opis:
Skin injuries are a health problem and can lead to serious, significant deterioration in the quality of life and, consequently, even illness and disability. Therefore, after wounding, immediate regeneration of the tissue is necessary to avoid further complications and pathogenesis. Consequently, many wound healing strategies have been developed, leading to the progress in constructing of multifunctional tissue substitutes for the skin, biomembranes, scaffolds and intelligent dressings. The field of science focusing on the creation of the above-mentioned products is tissue engineering (TE). Its main goal is to find a system that is able to replace or be a model that perfectly mimics the form and function of the skin. Research carried out on such constructs is mainly based on the analysis of mechanical properties (porosity, elasticity), as well as the assessment of the impact of individual components on processes related to the formation of new tissue as cell proliferation and differentiation, proliferation, angiogenesis - through in vivo studies (using animal models: mice, New Zealand rabbits) and in vitro (most often using mouse fibroblasts - L929). Skin constructions may have potential applications as wound dressings or skin substitutes in cases of severe skin damage.
Źródło:
Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia; 2018, 73, 1; 51-60
2083-358X
Pojawia się w:
Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of chitosan, hyaluronic acid and/or titanium dioxide on the physicochemical characteristic of phospholipid film/glass surface
Autorzy:
Ładniak, Agata
Jurak, Małgorzata
Wiącek, Agnieszka Ewa
Powiązania:
https://bibliotekanauki.pl/articles/109601.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
chitosan
titanium dioxide
hyaluronic acid
phospholipid
adhesion
topography
Opis:
The production of preparations, whose destination action takes place in close proximity to living cells, increases the necessity to carry out studies concerning the determination of the biomaterial surface effect on the cellular response. In achieving this goal, physicochemical characteristic of the surface can be helpful. This can be established based on topography, chemical composition, wettability, and surface energy analysis. In addition, determining the changes of these properties which can occur as a result of surface modification will allow prediction of cell behaviour when contacting with biomaterial. In the study, the Langmuir-Blodgett technique was used. It enabled the transfer of the Langmuir monolayer formed from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) to a solid support. The DPPC film imitated a natural biological membrane capable of interacting with the components of the liquid subphase: chitosan (Ch), hyaluronic acid (HA) and/or titanium dioxide (TiO2). Depending on the type and strength of interactions of phospholipid molecules with the components of the subphase, the films obtained on the solid support were characterized by specific surface properties. Their characteristics based mainly on values of the work of adhesion in connection with films topography, allowed for statement that it is possible to form semi-interpenetrating Ch network in which HA is entrapped, contributing to the enhanced adhesion of the DPPC film, additionally intensified by TiO2 inclusion. This type of research permit for better understanding of the interactions at the interface, cell membrane-Ch/HA/TiO2 and can be important in the creation of a new generation of skin or tissue substitutes.
Źródło:
Physicochemical Problems of Mineral Processing; 2019, 55, 6; 1535-1548
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surface characteristics of dppc monolayers deposited from titanium dioxide–chitosan–hyaluronic acid subphases on a glass support
Autorzy:
Ładniak, Agata
Jurak, Małgorzata
Wiącek, Agnieszka Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1034201.pdf
Data publikacji:
2019
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
DPPC
chitosan
hyaluronic acid
surface free energy
titanium dioxide
topography
Opis:
The Langmuir-Blodgett technique was used to transfer the monolayers of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) from the subphase containing chitosan (Ch) and/or titanium(IV) oxide (TiO2) and/or hyaluronic acid (HA) on glass plates after a low-temperature air plasma treatment. The surface free energy and its components were determined on the basis of advancing and receding contact angle measurements of water (W), formamide (F), and diiodomethane (DM). To estimate the total surface free energy (), the contact angle hysteresis (CAH) model was used, and the obtained data were compared with the results calculated from the Lifshitz-van der Waals/acid–base (LWAB) approach. It was found that the subphase components modify the surface of the phospholipid monolayer by changing the type and magnitude of interactions. They were reflected as significant differences in the obtained values of total surface free energy and its components. These findings can help in the development of composite materials, thereby expanding the spectrum of applications for chitosan, TiO2, and HA, as well as understanding the interactions between biomaterial and cell.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2019, 24; 106 - 118
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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